Time- and compartment-resolved proteome profiling of the extracellular niche in lung injury and repair.
Wie die Lunge ihre Wunden heilt
How the lung repairs its wounds
||Prof. Dr. Oliver Eickelberg||
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Thus, our proteomic systems biology study assigns proteins to tissue compartments and uncovers their dynamic regulation upon lung injury and repair, potentially contributing to the development of anti-fibrotic strategies.
Core statement Pressemitteilung:
Neuherberg, July 14, 2015. Our lungs are permanently exposed to harmful environmental factors that can damage or even destroy their cells. In a specific regenerative process these injured cells must be replaced as soon as possible. In collaboration with colleagues from the Max Planck Institute (MPI) of Biochemistry, scientists at the Helmholtz Zentrum München have now, for the first time, gained detailed insights into the dynamic remodeling of the tissue during lung repair. The results have just been published in 'EMBO Molecular Systems Biology'.
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