PuSH - Publikationsserver des Helmholtz Zentrums München

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Abfrage Programm/Institut/Gruppe PSP-Element Kontakt Anhang Verwendung Publikation

A novel approach for the analysis of longitudinal profiles reveals delayed progression to type 1 diabetes in a subgroup of multiple-islet-autoantibody-positive children.


Titel Pressemitteilung:

Antikörper verraten, wie schnell Kinder an Typ-1-Diabetes erkranken

Antibody dynamics reveal how fast type 1 diabetes develops in children

Oct 2016 IBB
zu Castell, Dr. Peter Achenbach PDF
PR 2016-07-01
Core statement:

We present a novel clustering algorithm that enables the stratification of individuals based on their longitudinal autoantibody patterns and reveals a subgroup of high-risk multiple autoantibody positive children with delayed progression to type 1 diabetes.


Core statement Pressemitteilung:

Antibody tests can detect the early stages of type I diabetes in affected children, even before the first symptoms of the disease occur. Researchers at the Helmholtz Zentrum München and the Paul Langerhans Institute in Dresden, both partner of the German Center for Diabetes Research, have shown that bioinformatics models can be used to obtain better predictions about the progression of the early stages of diabetes through to the clinically symptomatic disease. Their findings are reported in the medical journal ‘Diabetologia’.

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