PuSH - Publikationsserver des Helmholtz Zentrums München

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Abfrage Programm/Institut/Gruppe PSP-Element Kontakt Anhang Verwendung Publikation
Titel:

An ENU-induced mutation of miR-96 associated with progressive hearing loss in mice

Apr 2009 IEG
HDC
SAM
G-500600-003
Fuchs PDF
PM DE: PDF
PM EN: PDF
PR 2009-04-01
Publikation
Core statement:

Scientists of Helmholtz Zentrum München have developed a new mouse model that can be associated with deafness. With this model they succeeded for the first time in showing that microRNA, a new class of genes, influences hearing loss. The respective microRNA seed region influences the production of sensory hair cells in the inner ear, both in the mouse and in humans. The findings have been published ahead of print in the current online issue of Nature Genetics. This study represents a major step forward in elucidating the common phenomenon of progressive hearing loss, opening up new avenues for treatment.

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