PuSH - Publication Server of Helmholtz Zentrum München

2 Records found.
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Titel:

Helmholtz Zentrum München entschlüsselt molekularen Selbstschutz-Mechanismus

Oct 2010 IMI
EH
G-551000-001
Heissmeyer PDF PR 2010-07-01
Publication
Core statement:

Das Wissenschaftlerteam unter Leitung von Dr. Vigo Heissmeyer vom Institut für Molekulare Immunologie des Helmholtz Zentrums München hat einen molekularen Mechanismus entschlüsselt, der dazu beiträgt, den Organismus vor dem Angriff durch das eigene Immunsystem zu schützen und so Autoimmunkrankheiten wie Lupus erythematodes* zu verhindern.

Titel:

Roquin binds inducible costimulator mRNA and effectors of mRNA decay to induce microRNA-independent post-transcriptional repression

Oct 2010 IMI
EH
G-551000-001
Heissmeyer PDF WB 2010-12-01
AR 2010-12-01
Publication
Core statement:

We present the molecular mechanism by which Roquin prevents autoimmunity, this mechanism involves the binding of Roquin to ICOS mRNA as well as effectors of mRNA decay and does not depend on miRNA function.

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