PuSH - Publication Server of Helmholtz Zentrum München

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Titel:

Conformational flexibility of an essential RNA binding protein plays important roles for RNA binding

Oct 2014 STB
SAM
G-503000-001
Sattler PDF WB 2014-12-01
Publication
Core statement:

The essential splicing factor U2AF65 adopts a range of unbound conformations that include a pre-formed RNA-bound domain arrangement for specific recognition of intron RNA.

 

The study demonstrates that an essential RNA binding protein adopts a range of inactive conformations that play an important role for RNA binding.

 

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