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1.
Costa, R. et al.: Drug repurposing for WNT/beta-catenin induced lung repair in chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 197 (2018)
2.
Costa, R. et al.: Novel compounds for WNT/beta-catenin induced lung repair in chronic obstructive pulmonary disease. Eur. Respir. J. 52 (2018)
3.
Hu, Y.* et al.: The progenitor cell marker LGR5 is reduced in epithelial cells in emphysema. Am. J. Respir. Crit. Care Med. 197 (2018)
4.
Martin-Medina, A.* et al.: Increased extracellular vesicles mediate WNT5A signaling in idiopathic pulmonary fibrosis. Am. J. Respir. Crit. Care Med. 198, 1527-1538 (2018)
5.
Skronska-Wasek, W. ; Gosens, R.* ; Königshoff, M. & Baarsma, H.A.: WNT receptor signalling in lung physiology and pathology. Pharmacol. Ther., accepted (2018)
6.
Baarsma, H.A. et al.: Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD. J. Exp. Med. 214, 143-163 (2017)
7.
Baarsma, H.A. & Königshoff, M.: 'WNT-er is coming': WNT signalling in chronic lung diseases. Thorax 72, 746-759 (2017)
8.
Baarsma, H.A. et al.: Non-canonical Wnt-5a signaling impairs endogenous lung repair in COPD. Am. J. Respir. Crit. Care Med. 195 (2017)
9.
Skronska-Wasek, W. et al.: Reduced frizzled receptor 4 expression prevents WNT/β-catenin-driven alveolar lung repair in COPD. Am. J. Respir. Crit. Care Med. 196, 172-185 (2017)
10.
Baarsma, H.A. et al.: Non-canonical Wnt-5a compromises endogenous lung repair In COPD. Am. J. Respir. Crit. Care Med. 193 (2016)
11.
Ciolek, F. ; Königshoff, M. & Baarsma, H.A.: Regulation of non-canonical Wnt-5a by primary human lung fibroblasts. Am. J. Respir. Crit. Care Med. 193 (2016)
12.
Dietz, K. et al.: Age dictates a steroid resistant cascade of Wnt5a, transglutaminase-2 and leukotrienes in inflamed airways. J. Allergy Clin. Immunol. 139, 1343-1354.e6 (2016)
13.
Klee, S. ; Lehmann, M. ; Wagner, D.E. ; Baarsma, H.A. & Königshoff, M.: WISP1 mediates IL-6-dependent proliferation in primary human lung fibroblasts. Sci. Rep. 6:20547 (2016)
14.
Klee, S. ; Lehmann, M. ; Wagner, D.E. ; Baarsma, H.A. & Königshoff, M.: Wisp1 mediates Il6-dependent proliferation in healthy and Ipf-derived primary human lung fibroblasts. Am. J. Respir. Crit. Care Med. 193 (2016)
15.
Liu, X. et al.: Systematic identification of pharmacological targets from small-molecule phenotypic screens. Cell Chem. Bio. 23, 1302-1313 (2016)
16.
Ota, C. ; Baarsma, H.A. ; Wagner, D.E. ; Hilgendorff, A. & Königshoff, M.: Linking bronchopulmonary dysplasia to adult chronic lung diseases: Role of WNT signaling. Mol. Cell. Pediatr. 3, 34:34 (2016)
17.
Skronska-Wasek, W. et al.: Cigarette smoke-induced downregulation of the epithelial cell enriched WNT receptor Fzd4 contributes to reduced Wnt/beta-catenin signaling and alveolar epithelial cell proliferation in COPD. Am. J. Respir. Crit. Care Med. 193 (2016)
18.
Spanjer, A.I.* et al.: TGF-β-induced profibrotic signaling is regulated in part by the WNT receptor Frizzled-8. FASEB J. 30, 1823-1835 (2016)
19.
Baarsma, H.A. ; Boczkowski, J.* ; Yildirim, A.Ö. & Königshoff, M.: Age-related Wnt5a contributes to disturbed alveolar epithelial cell repair in COPD. Am. J. Respir. Crit. Care Med. 191:A5572 (2015)
20.
Berschneider, B. et al.: miR-92a regulates TGF-β1-induced WISP1 expression in pulmonary fibrosis. Int. J. Biochem. Cell Biol. 53, 432-441 (2014)