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1.
Boege, Y.* et al.: A dual role of caspase-8 in triggering and sensing proliferation-associated DNA damage, a key determinant of liver cancer development. Cancer Cell 32, 342-359.e10 (2017)
2.
Weber, A. et al.: A linear diubiquitin-based probe for efficient and selective detection of the deubiquitinating enzyme OTULIN. Cell Chem. Bio. 24, 1299-1313.e7 (2017)
3.
Berger, E.* et al.: Mitochondrial function controls intestinal epithelial stemness and proliferation. Nat. Commun. 7:13171 (2016)
4.
Finan, B. et al.: Chemical hybridization of glucagon and thyroid hormone optimizes therapeutic Impact for metabolic disease. Cell 167, 843-857.e14 (2016)
5.
Ma, C.* et al.: NAFLD causes selective CD4+ T lymphocyte loss and promotes hepatocarcinogenesis. Nature 531, 253-257 (2016)
6.
Matter, M.S.* et al.: Oncogenic driver genes and the inflammatory microenvironment dictate liver tumor phenotype. Hepatology 63, 1888-1899 (2016)
7.
Scherr, A.L.* et al.: Bcl-xL is an oncogenic driver in colorectal cancer. Cell Death Dis. 7:e2342 (2016)
8.
Stelzer, D.* et al.: Impact of posaconazol liquid vs. tablet formulation on plasma trough levels in lung transplant recipients. Am. J. Respir. Crit. Care Med. 193 (2016)
9.
Sunami, Y.* et al.: Canonical NF-kappa B signaling in hepatocytes acts as a tumor-suppressor in hepatitis B virus surface antigen-driven hepatocellular carcinoma by controlling the unfolded protein response. Hepatology 63, 1, 233A-233A (2016)
10.
Berger, E.* et al.: Mitochondrial dysfunction impairs epithelial proliferative control and stemness in the intestinal crypts. J. Crohns Colitis 9, S104 (2015)
11.
Finkin, S.* et al.: Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma. Nat. Immunol. 16, 1235-1244 (2015)
12.
Friemel, J.* et al.: Intratumor heterogeneity in hepatocellular carcinoma. Clin. Cancer Res. 21, 1951-1961 (2015)
13.
Garnelo, M.* et al.: Interaction between tumour-infiltrating B cells and T cells controls the progression of hepatocellular carcinoma. Gut 66, 342-351 (2015)
14.
Mu, X.* et al.: Hepatocellular carcinoma originates from hepatocytes and not from the progenitor/biliary compartment. J. Clin. Invest. 125, 3891-3903 (2015)
15.
Protzer, U. et al.: Molecular detection of Hepatitis E Virus (HEV) in liver biopsies after liver transplantation. Mod. Pathol. 28, 523-532 (2015)
16.
Weber, A.* ; O'Connor, T.* & Heikenwälder, M.: Next generation of preclinical liver cancer models. Clin. Cancer Res. 21, 4254-4256 (2015)
17.
Jeltsch, K. et al.: Cleavage of roquin and regnase-1 by the paracaspase MALT1 releases their cooperatively repressed targets to promote TH17 differentiation. Nat. Immunol. 15, 1079-1089 (2014)
18.
Ringelhan, M. ; Reisinger, F. ; Yuan, D.T. ; Weber, A.* & Heikenwälder, M.: Modeling human liver cancer heterogeneity: Virally induced transgenic models and mouse genetic models of chronic liver inflammation. Curr. Protoc. Pharmacol. 67, 14.31.1-14.31.17 (2014)
19.
Wolf, M.J.* et al.: Metabolic activation of intrahepatic CD8+ T cells and NKT cells causes nonalcoholic steatohepatitis and liver cancer via cross-talk with hepatocytes. Cancer Cell 26, 549-564 (2014)
20.
Vucur, M.* et al.: RIP3 inhibits inflammatory hepatocarcinogenesis but promotes cholestasis by controlling caspase-8- and JNK-dependent compensatory cell proliferation. Cell Rep. 4, 776-790 (2013)