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Biagosch, C. et al.: Elevated glutaric acid levels in Dhtkd1-/Gcdh- double knockout mice challenge our current understanding of lysine metabolism. Biochim. Biophys. Acta 1863, 2220-2228 (2017)
Bowl, M.R.* et al.: A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction. Nat. Commun. 8:886 (2017)
Kaloff, C. et al.: Genome wide conditional mouse knockout resources. Drug Discov. Today, accepted (2017)
Weber, T. et al.: Caspase-mediated apoptosis induction in zebrafish cerebellar Purkinje neurons. Development 143, 4279-4287 (2016)
Wefers, B. ; Brandl, C. ; Ortiz, O. ; Wurst, W. & Kühn, R.: Genome editing in mice using TALE nucleases. Methods Mol. Biol. 1338, 229-243 (2016)
Brandl, C. et al.: Creation of targeted genomic deletions using TALEN or CRISPR/Cas nuclease pairs in one-cell mouse embryos. FEBS Open Bio 5, 26-35 (2015)
Chu, V.T.* et al.: Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells. Nat. Biotechnol. 33, 543-548 (2015)
Truong, D.J.J. et al.: Development of an intein-mediated split-Cas9 system for gene therapy. Nucleic Acids Res. 43, 6450-6458 (2015)
Kühn, R. ; Brandl, C. ; Ortiz, O. & Wurst, W.: Generation of targeted deletions in mouse zygotes by pairs of TALENs or SGRNAS/Cas9. Transgenic Res. 23, 870 (2014)
Meier, F. et al.: FGF/FGFR2 signaling regulates the generation and correct positioning of Bergmann glia cells in the developing mouse cerebellum. PLoS ONE 9:e101124 (2014)
Pertek, A. et al.: Simple derivation of transgene-free iPS cells by a dual recombinase approach. Mol. Biotechnol. 56, 697-713 (2014)
Wefers, B. ; Ortiz, O. ; Wurst, W. & Kühn, R.: Generation of targeted mouse mutants by embryo microinjection of TALENs. Methods 69, 94-101 (2014)
Bolze, F.* et al.: Characterization of the melanocortin-4-receptor nonsense mutation W16X in vitro and in vivo. Pharmacogenomics J. 13, 80-93 (2013)
Kim, J. et al.: An RNAi-based approach to down-regulate a gene family in vivo. PLoS ONE 8:e80312 (2013)
Kleinhammer, A. ; Wurst, W. & Kühn, R.: Target validation in mice by constitutive and conditional RNAi. Methods Mol. Biol. 986, 307-323 (2013)
Merkl, C.* et al.: Efficient generation of rat induced pluripotent stem cells using a non-viral inducible vector. PLoS ONE 8:e55170 (2013)
Ortiz, O. ; Wurst, W. & Kühn, R.: Reversible and tissue-specific activation of MAP kinase signaling by tamoxifen in brafV637 ERT2 mice. Genesis 51, 448-455 (2013)
Panda, S. et al.: Highly efficient targeted mutagenesis in mice using TALENs. Genetics 195, 703-713 (2013)
Wefers, B. et al.: Gene editing in one-cell embryos by zinc-finger and TAL nucleases. In: Auwerx, J.* ; Ackerman, S.L.* ; Brown, S.D.* ; Justice, M.* ; Moore, D.D.* ; Nadeau, J.* [Eds.]: Current Protocols in Mouse Biology. Weinheim: Wiley-VCH, 2013. 347-364 ( ; 2)