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1.
Tepper, S.* et al.: Restriction of AID activity and somatic hypermutation by PARP-1. Nucleic Acids Res., accepted (2019)
2.
Hinrichs, A.* et al.: Growth hormone receptor-deficient pigs resemble the pathophysiology of human Laron syndrome and reveal altered activation of signaling cascades in the liver. Mol. Metab. 11, 113-128 (2018)
3.
Rehage, N. et al.: Binding of NUFIP2 to Roquin promotes recognition and regulation of ICOS mRNA. Nat. Commun. 9:299 (2018)
4.
Reiter, K.* et al.: Tyrosine kinase inhibition increases the cell surface localization of FLT3-ITD and enhances FLT3-directed immunotherapy of acute myeloid leukemia. Leukemia 32, 313-322 (2018)
5.
Stief, S.M.* et al.: Loss of KDM6A confers drug resistance in acute myeloid leukemia. Blood 132 (2018)
6.
Essig, K.* et al.: Roquin suppresses the PI3K-mTOR signaling pathway to inhibit T helper cell differentiation and conversion of treg to Tfr cells. Immunity 47, 1067-1082.e12 (2017)
7.
Gressel, S.* et al.: CDK9-dependent RNA polymerase II pausing controls transcription initiation. eLife 6:e29736 (2017)
8.
Schlenker, R. et al.: Chimeric PD-1:28 receptor upgrades low-avidity T cells and restores effector function of tumor-infiltrating lymphocytes for adoptive cell therapy. Cancer Res. 77, 3577-3590 (2017)
9.
Bauer, C.* et al.: Phosphorylation of TET proteins is regulated via O-GlcNAcylation by the glycosyltransferase OGT. J. Biol. Chem. 290, 4801-4812 (2015)
10.
Mulholland, C.B.* et al.: A modular open platform for systematic functional studies under physiological conditions. Nucleic Acids Res. 43:e112 (2015)
11.
Reiter, K. et al.: Visualization of AML-specific FLT3 mutants and differential downstream signaling. Ann. Hematol. 94, S82 (2015)
12.
Reiter, K. et al.: Tyrosin kinase inhibition restores the membrane localization of FLT3-ITD. Blood 126 (2015)
13.
Roth, S.* et al.: Rad50-CARD9 interactions link cytosolic DNA sensing to IL-1β production. Nat. Immunol. 15, 538-545 (2014)
14.
Schneider, K.* et al.: Dissection of cell cycle-dependent dynamics of Dnmt1 by FRAP and diffusion-coupled modeling. Nucleic Acids Res. 41, 4860-4876 (2013)
15.
Wolf, A. et al.: The poly-serine domain of the lysyl-5 hydroxylase Jmjd6 mediates subnuclear localization. Biochem. J. 453, 357-370 (2013)
16.
Bönisch, C.* et al.: H2A.Z.2.2 is an alternatively spliced histone H2A.Z variant that causes severe nucleosome destabilization. Nucleic Acids Res. 40, 5951-5964 (2012)
17.
Gross, H.* et al.: Binding of the heterogeneous ribonucleoprotein K (hnRNP K) to the Epstein-Barr virus nuclear antigen 2 (EBNA2) enhances viral LMP2A expression. PLoS ONE 7:e42106 (2012)
18.
Hochstatter, J.* et al.: Myb-binding protein 1a (Mybbp1a) regulates levels and processing of pre-ribosomal RNA. J. Biol. Chem. 287, 24365-24377 (2012)
19.
Jost, K.L.* et al.: Generation and characterization of rat and mouse monoclonal antibodies specific for MeCP2 and their use in X-inactivation studies. PLoS ONE 6:e26499 (2012)
20.
Konstandin, N.P. et al.: Genomic 5-hydroxymethylcytosine levels correlate with TET2 mutations and a distinct global gene expression pattern in secondary acute myeloid leukemia. Leukemia 25, 1649-1652 (2011)