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1.
Ostertag, M.S. ; Messias, A.C. ; Sattler, M. & Popowicz, G.M.: The structure of the SPOP-Pdx1 interface reveals insights into the phosphorylation-dependent binding regulation. Structure 27, 327-334.e3 (2019)
2.
Harrison, L. et al.: Fluorescent blood–brain barrier tracing shows intact leptin transport in obese mice. Int. J. Obes., accepted (2018)
3.
Iuso, A. et al.: Mutations in PPCS, encoding phosphopantothenoylcysteine synthetase, cause autosomal-recessive dilated cardiomyopathy. Am. J. Hum. Genet. 102, 1018-1030 (2018)
4.
Kyriakou, E. et al.: Celastrol promotes weight loss in diet-induced obesity by inhibiting the protein tyrosine phosphatases PTP1B and TCPTP in the hypothalamus. J. Med. Chem. 61, 11144-11157 (2018)
5.
Pfuhlmann, K. et al.: Celastrol-induced weight loss is driven by hypophagia and independent from UCP1. Diabetes 67, 2456-2465 (2018)
6.
Jung, B. et al.: Pitchfork and Gprasp2 target smoothened to the primary cilium for Hedgehog pathway activation. PLoS ONE 11:e0149477 (2016)
7.
Jung, B. et al.: Novel small molecules targeting ciliary transport of smoothened and oncogenic Hedgehog pathway activation. Sci. Rep. 6:22540 (2016)
8.
Vincendeau, M. et al.: Inhibition of canonical NF-κB signaling by a small molecule targeting NEMO-ubiquitin interaction. Sci. Rep. 6:18934 (2016)
9.
Gilsbach, B.K.* et al.: Structural characterization of LRRK2 inhibitors. J. Med. Chem. 58, 3751-3756 (2015)
10.
Xu, T. et al.: Effects of metformin on metabolite profiles and LDL cholesterol in patients with type 2 diabetes. Diabetes Care 38, 1858-1867 (2015)
11.
Wang-Sattler, R. et al.: Novel biomarkers for pre-diabetes identified by metabolomics. Mol. Syst. Biol. 8:615 (2012)