Ashton, M.P.* ; Eugster, A.* ; Dietz, S.* ; Loebel, D.* ; Lindner, A.* ; Kuehn, D.* ; Taranko, A.E.* ; Heschel, B.* ; Gavrisan, A.* ; Ziegler, A.-G. ; Aringer, M.* ; Bonifacio, E.*
Association of dendritic cell signatures with autoimmune inflammation revealed by single-cell profiling.
Arthritis Rheum. 71, 817-828 (2019)
Eugster, A.* ; Kraus, G.* ; Lidzba, V.* ; Müller, D.* ; Jolink, M. ; Ziegler, A.-G. ; Bonifacio, E.
Cytoplasmic ends of tetraspanin 7 harbour epitopes recognised by autoantibodies in type 1 diabetes.
Diabetologia 62, 805-810 (2019)
Hippich, M. ; Beyerlein, A. ; Hagopian, W.A.* ; Krischer, J.P.* ; Vehik, K.* ; Knoop, J. ; Winker, C. ; Toppari, J.* ; Lernmark, Å.* ; Rewers, M.J.* ; Steck, A.K.* ; She, J.X.* ; Akolkar, B.* ; Robertson, C.C.* ; Onengut-Gumuscu, S.* ; Rich, S.S.* ; Bonifacio, E.* ; Ziegler, A.-G. ; The Teddy Study Group*
Genetic contribution to the divergence in type 1 diabetes risk between children from the general population and children from affected families.
Diabetes 68, 847-857 (2019)
Hörber, S. ; Achenbach, P. ; Schleicher, E. ; Peter, A.
Harmonization of immunoassays for biomarkers in diabetes mellitus.
Biotechnol. Adv., accepted (2019)
Jacobsen, L.M.* ; Elding Larsson, H.* ; Tamura, R.N.* ; Vehik, K.* ; Clasen, J.* ; Sosenko, J.M.* ; Hagopian, W.A.* ; She, J.X.* ; Steck, A.K.* ; Rewers, M.* ; Simell, O.* ; Toppari, J.* ; Veijola, R.* ; Ziegler, A.-G. ; Krischer, J.P.* ; Akolkar, B.* ; Haller, M.J.* ; The Teddy Study Group*
Predicting progression to type 1 diabetes from ages 3 to 6 in islet autoantibody positive TEDDY children.
Pediatr. Diabetes 20, 263-270 (2019)
Laimighofer, M. ; Lickert, R. ; Fuerst, R. ; Theis, F.J. ; Winkler, C. ; Bonifacio, E.* ; Ziegler, A.-G. ; Krumsiek, J.
Common patterns of gene regulation associated with Cesarean section and the development of islet autoimmunity - indications of immune cell activation.
Sci. Rep. 9:6250 (2019)
Peplow, C. ; Assfalg, R. ; Beyerlein, A. ; Hasford, J.* ; Bonifacio, E.* ; Ziegler, A.-G.
Blood draws up to 3% of blood volume in clinical trials are safe in children.
Acta Paediatr. 108, 940-944 (2019)
Pigeot, I.* ; Foraita, R.* ; Frömke, C.* ; Haller, B.* ; Hoffmann, V. ; Zapf, A.*
Ethical consideration of studies involving human subjects outside the regulatory framework: not mandatory, but of high relevance.
Bundesgesundheitsbl.-Gesund., accepted (2019)
Pröhl, H.* ; Scherm, M.G. ; Meneses, S.* ; Dreher, C.E.* ; Meuche, I.* ; Rodríguez, A.*
Female-female aggression is linked to food defence in a poison frog.
Ethol. 125, 222-231 (2019)
Silvis, K.* ; Aronsson, C.A.* ; Liu, X.* ; Uusitalo, U.* ; Yang, J.* ; Tamura, R.* ; Lernmark, A.* ; Rewers, M.* ; Hagopian, W.* ; She, J.X.* ; Simell, O.* ; Toppari, J.* ; Ziegler, A.-G. ; Akolkar, B.* ; Krischer, J.* ; Virtanen, S.M.* ; Norris, J.M.* ; Teddy Study Group*
Maternal dietary supplement use and development of islet autoimmunity in the offspring: TEDDY study.
Pediatr. Diabetes 20, 86-92 (2019)
Ungethüm, K. ; Jolink, M. ; Hippich, M. ; Lachmann, L. ; Haupt, F. ; Winkler, C. ; Hummel, S. ; Pitchika, A. ; Kordonouri, O.* ; Ziegler, A.-G. ; Beyerlein, A.
Physical activity is associated with lower insulin and C-peptide during glucose challenge in children and adolescents with family background of diabetes.
Diabetic Med. 36, 366-375 (2019)
Winkler, C.
Infantile vitamin-D-levels determine the risk for type 1-diabetes.
Diabetes Stoffwechs. Herz 28, 33-35 (2019)
Ziegler, A.-G. ; Hoffmann, G.F.* ; Hasford, J. ; Larsson, H.E.* ; Danne, T.* ; Berner, R.* ; Penno, M.* ; Koralova, A.* ; Dunne, J.* ; Bonifacio, E.*
Screening for asymptomatic β-cell autoimmunity in young children.
Lancet Child Adolesc. Health 3, 288-290 (2019)
Achenbach, P. ; Hawa, M.I.* ; Krause, S. ; Lampasona, V.* ; Jerram, S.T.* ; Williams, A.J.K.* ; Bonifacio, E.* ; Ziegler, A.-G. ; Leslie, R.D.*
Autoantibodies to N-terminally truncated GAD improve clinical phenotyping of individuals with adult-onset diabetes: Action LADA 12.
Diabetologia 61, 1644-1649 (2018)
Achenbach, P.
Früherkennung und präventive Behandlung des Typ-1-Diabetes.
Diabetologe 14, 212-213 (2018)
Achenbach, P.
Typ-1-Diabetes im asymptomatischen Frühstadium: Orales Insulin zur präventiven Behandlung.
Diabetologe 14, 234-239 (2018)
Beyerlein, A. ; Lack, N.* ; von Kries, R.*
No further improvement in pregnancy-related outcomes in the offspring of mothers with pre-gestational diabetes in Bavaria, Germany, between 2001 and 2016.
Diabetic Med. 35, 1420-1424 (2018)
Beyerlein, A. ; Jolink, M.
Evaluation of the Fr1da screening: From an epidemiological perspective.
Diabetologe 14, 221-223 (2018)
Beyerlein, A. ; Bonifacio, E.* ; Vehik, K.* ; Hippich, M. ; Winkler, C. ; Frohnert, B.I.* ; Steck, A.K.* ; Hagopian, W.A.* ; Krischer, J.P.* ; Lernmark, Å.* ; Rewers, M.J.* ; She, J.X.* ; Toppari, J.* ; Akolkar, B.* ; Rich, S.S.* ; Ziegler, A.-G.
Progression from islet autoimmunity to clinical type 1 diabetes is influenced by genetic factors: Results from the prospective TEDDY study.
J. Med. Genet., accepted (2018)
Bohn, B.* ; Bramlage, P.* ; Wagner, C.* ; Kaltheuner, M.* ; Welp, R.* ; Sziegoleit, S.* ; Zimmermann, A.* ; Reuter, H.M.* ; Hummel, M. ; Gloyer, J.* ; Holl, R.W.* ; Danne, T.*
Welche Patienten aus der Routinebetreuung verwenden das neue Insulin-Analogon Glargin U300 im Vergleich zu Patienten mit Glargin U100? Eine multizentrische Analyse von 14.123 Patienten mit Insulin Glargin aus den Diabetesregistern DPV und DIVE.  
Wien. Med. Wochenschr. 168, 415–422 (2018)
Bonifacio, E.* ; Beyerlein, A. ; Hippich, M. ; Winkler, C. ; Vehik, K.* ; Weedon, M.N.* ; Laimighofer, M. ; Hattersley, A.T.* ; Krumsiek, J. ; Frohnert, B.I.* ; Steck, A.K.* ; Hagopian, W.A.* ; Krischer, J.P.* ; Lernmark, A.* ; Rewers, M.J.* ; She, J.X.* ; Toppari, J.* ; Akolkar, B.* ; Oram, R.A.* ; Rich, S.S.* ; Ziegler, A.-G.
Genetic scores to stratify risk of developing multiple islet autoantibodies and type 1 diabetes: A prospective study in children.
PLoS Med. 15:e1002548 (2018)
Couper, J.J.* ; Haller, M.J.* ; Greenbaum, C.J.* ; Ziegler, A.-G. ; Wherrett, D.K.* ; Knip, M.* ; Craig, M.E.*
ISPAD Clinical Practice Consensus Guidelines 2018: Stages of type 1 diabetes in children and adolescents.
Pediatr. Diabetes 19, 20-27 (2018)
Endesfelder, D. ; zu Castell, W. ; Bonifacio, E.* ; Rewers, M.* ; Hagopian, W.A.* ; She, J.X.* ; Lernmark, A.* ; Toppari, J.* ; Vehik, K.* ; Williams, A.J.K.* ; Yu, L.* ; Akolkar, B.* ; Krischer, J.P.* ; Ziegler, A.-G. ; Achenbach, P.
Time-resolved autoantibody profiling facilitates stratification of preclinical type 1 diabetes in children.
Diabetes 68, 119-130 (2018)
Frohnert, B.I.* ; Laimighofer, M. ; Krumsiek, J. ; Theis, F.J. ; Winkler, C. ; Norris, J.M.* ; Ziegler, A.-G. ; Rewers, M.J.* ; Steck, A.K.*
Prediction of type 1 diabetes using a genetic risk model in the Diabetes Autoimmunity Study in the Young.
Pediatr. Diabetes 19, 277-283 (2018)
Hartmann, B.* ; Bramlage, P.* ; Lanzinger, S.* ; Danne, T.* ; Hummel, M. ; Kaltheuner, M.* ; Raddatz, D.* ; Rathmann, W.* ; Reuter, H.M.* ; Seufert, J.* ; Holl, R.W.*
Regional differences in type 2 diabetes treatment and outcomes in Germany-An analysis of the German DPV and DIVE registries.
Diabetes Metab. Res. Rev. 34:e3049 (2018)
Heinrich, M. ; Maison, N. ; Achenbach, P. ; Assfalg, R. ; Braig, S.* ; Böcker, D.* ; Dunstheimer, D.* ; Ermer, U.* ; Gavazzeni, A.* ; Gerstl, E.M.* ; Hummel, S. ; Kick, K. ; Müller, H.* ; Nellen-Hellmuth, N.* ; Ockert, C.* ; Sindichakis, M.* ; Tretter, S.* ; Warncke, K.* ; Ziegler, A.-G. ; Beyerlein, A.
Fasting hypoglycemia is associated with disease progression in presymptomatic early stage type 1 diabetes.
Pediatr. Diabetes 19, 1238-1242 (2018)
Heussinger, N.* ; Della Marina, A.* ; Beyerlein, A. ; Leiendecker, B.* ; Hermann-Alves, S.* ; Dalla Pozza, R.* ; Klepper, J.*
10 patients, 10 years - Long term follow-up of cardiovascular risk factors in Glut1 deficiency treated with ketogenic diet therapies: A prospective, multicenter case series.
Clin. Nutr. 37, 2246-2251 (2018)
Hippich, M. ; Oleynik, A.* ; Jain, K.* ; Winkler, C. ; Ferreira, R.C.* ; Bonifacio, E.* ; Ziegler, A.-G. ; Briese, T.*
Searching peripheral blood mononuclear cells of children with viral respiratory tract infections preceding islet autoimmunity for viruses by high-throughput sequencing.
Acta Diabetol. 55, 881-884 (2018)
Holthaus, L. ; Lamp, D. ; Gavrisan, A. ; Sharma, V.* ; Ziegler, A.-G. ; Jastroch, M. ; Bonifacio, E.
CD4+ T cell activation, function, and metabolism are inhibited by low concentrations of DMSO.
J. Immunol. Methods 463, 54-60 (2018)
Hummel, S. ; Beyerlein, A. ; Pfirrmann, M.* ; Hofelich, A. ; Much, D. ; Hivner, S. ; Bunk, M. ; Herbst, M.* ; Peplow, C. ; Walter, M.* ; Kohn, D.* ; Hummel, N. ; Kratzsch, J.* ; Hummel, M.* ; Füchtenbusch, M.* ; Hasford, J.* ; Ziegler, A.-G.
Efficacy of vildagliptin for prevention of postpartum diabetes in women with a recent history of insulin-requiring gestational diabetes: A phase II, randomized, double-blind, placebo-controlled study.
Mol. Metab. 9, 168-175 (2018)
Jarasch, A. ; Glaser, A. ; Häring, H.-U. ; Roden, M.* ; Schürmann, A.* ; Solimena, M. ; Theis, F.J. ; Tschöp, M.H. ; Wess, G. ; Hrabě de Angelis, M.
Big data for personalized diabetes prevention.
Diabetologe 14, 486-492 (2018)
Kick, K.* ; Ziegler, A.-G.
Immune preventive approaches for type-1-diabetes.
Med. Monatsschr. Pharm. 41, 105-109 (2018)
Kick, K.* ; Assfalg, R. ; Aydin, S.* ; Bechtold-Dalla Pozza, S.* ; Böcker, D.* ; Braig, S.* ; Bunk, M.* ; Dunstheimer, D.* ; Durmashkina, A.* ; Ermer, U.* ; Gavazzeni, A.* ; Gerstl, E.M.* ; Heinrich, M.* ; Herbst, M. ; Kriesen, Y.* ; Kuhnle-Krahl, U.* ; Müller, H.* ; Nellen-Hellmuth, N.* ; Ockert, C.* ; Ramminger, C.* ; Sindichakis, M.* ; Tretter, S.* ; Warncke, K.* ; Achenbach, P. ; Ziegler, A.-G. ; Hoffmann, V.
Recruiting young pre-symptomatic children for a clinical trial in type 1 diabetes: Insights from the Fr1da insulin intervention study.
Contemp. Clin. Trails Comm. 11, 170-173 (2018)
Kick, K.* ; Hoffmann, V. ; Lange, K.* ; Lang, M.* ; Laub, O.* ; Bechtold-Dalla Pozza, S.* ; Böcker, D.* ; Braig, S.* ; Dietz, B.* ; Dunstheimer, D.* ; Eber, S.* ; Ermer, U.* ; Gavazzeni, A.* ; Gerstl, E.M.* ; Götz, M.* ; Huhn, F.* ; Kuhnle-Krahl, U.* ; Landendörfer, W.* ; Leipold, G.* ; Leppik, K.-H.* ; Müller, H.* ; Müller, I.* ; Nellen-Hellmuth, N.* ; Ockert, C.* ; Renner, C.* ; Sindichakis, M.* ; Tretter, S.* ; Warncke, K. ; Winkler, C. ; Zeller, S.* ; Achenbach, P. ; Ziegler, A.-G.
Feasibility and organization of a population-based screening for pre-symptomatic type 1 diabetes in children – Evaluation of the Fr1da study.
J. Public Health, accepted (2018)
Kindt, A. ; Fuerst, R.W. ; Knoop, J. ; Laimighofer, M. ; Telieps, T. ; Hippich, M. ; Woerheide, M.A. ; Wahl, S. ; Wilson, R. ; Sedlmeier, E.-M. ; Hommel, A.* ; Todd, J.A.* ; Krumsiek, J. ; Ziegler, A.-G. ; Bonifacio, E.
Allele-specific methylation of type 1 diabetes susceptibility genes.
J. Autoimmun. 89, 63-74 (2018)
Köhler, M. ; Umlauf, N.* ; Greven, S.*
Nonlinear association structures in flexible Bayesian additive joint models.
Stat. Med. 37, 4771-4788 (2018)
Liberati, D.* ; Wyatt, R.C.* ; Brigatti, C.* ; Marzinotto, I.* ; Ferrari, M.* ; Bazzigaluppi, E.* ; Bosi, E.* ; Gillard, B.T.* ; Gillespie, K.M.* ; Gorus, F.* ; Weets, I.* ; Balti, E.* ; Piemonti, L.* ; Achenbach, P. ; Williams, A.J.K.* ; Lampasona, V.*
A novel LIPS assay for insulin autoantibodies.
Acta Diabetol. 55, 263–270 (2018)
Long, A.E.* ; Wilson, I.V.* ; Becker, D.J.* ; Libman, I.M.* ; Arena, V.C.* ; Wong, F.S.* ; Steck, A.K.* ; Rewers, M.J.* ; Yu, L.* ; Achenbach, P. ; Casas, R.* ; Ludvigsson, J.* ; Williams, A.J.K.* ; Gillespie, K.M.*
Characteristics of slow progression to diabetes in multiple islet autoantibody-positive individuals from five longitudinal cohorts: The SNAIL study.
Diabetologia 61, 1484–1490 (2018)
Lynch, K.F.* ; Lee, H.S.* ; Törn, C.* ; Vehik, K.* ; Krischer, J.P.* ; Larsson, H.E.* ; Haller, M.J.* ; Hagopian, W.A.* ; Rewers, M.J.* ; She, J.X.* ; Simell, O.G.* ; Toppari, J.* ; Ziegler, A.-G. ; Akolkar, B.* ; Hyöty, H.* ; Bonifacio, E.* ; Lernmark, A.*
Gestational respiratory infections interacting with offspring HLA and CTLA-4 modifies incident beta-cell autoantibodies.
J. Autoimmun. 86, 93-103 (2018)
Mathieu, C.* ; Lahesmaa, R.* ; Bonifacio, E. ; Achenbach, P. ; Tree, T.*
Immunological biomarkers for the development and progression of type 1 diabetes.
Diabetologia 61, 2252-2258 (2018)
Mehdi, A.M.* ; Hamilton-Williams, E.E.* ; Cristino, A.* ; Ziegler, A.-G. ; Bonifacio, E.* ; Le Cao, K.A.* ; Harris, M.H.* ; Thomas, R.*
A peripheral blood transcriptomic signature predicts autoantibody development in infants at risk of type 1 diabetes.
JCI insight 3:e98212 (2018)
Müller, D.* ; Telieps, T. ; Eugster, A.* ; Weinzierl, C. ; Jolink, M. ; Ziegler, A.-G. ; Bonifacio, E.
Novel minor HLA DR associated antigens in type 1 diabetes.
Clin. Immunol. 194, 87-91 (2018)
Norris, J.M.* ; Lee, H.S.* ; Frederiksen, B.* ; Erlund, I.* ; Uusitalo, U.* ; Yang, J.A.* ; Lernmark, A.* ; Simell, O.* ; Toppari, J.* ; Rewers, M.* ; TEDDY Study Group (Ziegler, A.-G.) ; She, J.X.* ; Onengut-Gumuscu, S.* ; Chen, W.M.* ; Rich, S.S.* ; Sundvall, J.* ; Akolkar, B.* ; Krischer, J.* ; Virtanen, S.M.* ; Hagopian, W.*
Plasma 25-hydroxyvitamin D concentration and risk of islet autoimmunity.
Diabetes 67, 146-154 (2018)
Pfirrmann, M.* ; Baccarani, M.* ; Saussele, S.* ; Faber, E.* ; Bogdanovic, A.* ; Clark, R.* ; Hehlmann, R.* ; Hoffmann, V.
The EUTOS long-term survival (ELTS) score is superior to the Sokal score for prognosis of probabilities of dying of chronicphase chronic myeloid leukaemia.
Oncol. Res. Treat. 41, 140-141 (2018)
Pitchika, A. ; Jolink, M. ; Winkler, C. ; Hummel, S. ; Hummel, N. ; Krumsiek, J. ; Kastenmüller, G. ; Raab, J. ; Kordonouri, O.* ; Ziegler, A.-G. ; Beyerlein, A.
Associations of maternal type 1 diabetes with childhood adiposity and metabolic health in the offspring: A prospective cohort study.
Diabetologia 61, 2319–2332 (2018)
Pitchika, A. ; Vehik, K.* ; Hummel, S. ; Norris, J.M.* ; Uusitalo, U.M.* ; Yang, J.* ; Virtanen, S.M.* ; Koletzko, S.* ; Aronsson, C.A.* ; Ziegler, A.-G. ; Beyerlein, A.
Associations of maternal diabetes during pregnancy with overweight in offspring: Results from the prospective TEDDY study.
Obesity 26, 1457-1466 (2018)
Rewers, M.* ; Hyöty, H.* ; Lernmark, Å.* ; Hagopian, W.* ; She, J.X.* ; Schatz, D.* ; Ziegler, A.-G. ; Toppari, J.* ; Akolkar, B.* ; Krischer, J.*
The Environmental Determinants of Diabetes in the Young (TEDDY) Study: 2018 Update.
Curr. Diab. Rep. 18:136 (2018)
Riikonen, A.* ; Hadley, D.* ; Uusitalo, U.* ; Miller, N.* ; Koletzko, S.* ; Yang, J.* ; Andrén Aronsson, C.* ; Hummel, S. ; Norris, J.M.* ; Virtanen, S.M.*
Milk feeding and first complementary foods during the first year of life in the TEDDY study.
Matern. Child Nutr. 14:e12611 (2018)
Rodriguez-Calvo, T.
Enteroviral infections as a trigger for type 1 diabetes.
Curr. Diab. Rep. 18:106 (2018)
Rodriguez-Calvo, T. ; Richardson, S.J.* ; Pugliese, A.*
Pancreas pathology during the natural history of type 1 diabetes.
Curr. Diab. Rep. 18:124 (2018)
Rodriguez-Calvo, T.
Enterovirus infection and type 1 diabetes: Unraveling the crime scene.
Clin. Exp. Immunol. 195, 15-24 (2018)
Salami, F.* ; Lee, H.* ; Freyhult, E.* ; Larsson, H.E.* ; Lernmark, A.* ; Törn, C.* ; TEDDY Study Group (Ziegler, A.-G. ; Beyerlein, A. ; Gavrisan, A. ; Gezginci, C. ; Hummel, M. ; Hummel, S. ; Knopff, A. ; Koletzko, S. ; Stock, J. ; Scholz, M. ; Roth, R. ; Warncke, K. ; Wendel, L. ; Winkler, C.)
Reduction in white blood cell, neutrophil, and red blood cell counts related to sex, HLA, and islet autoantibodies in Swedish TEDDY children at increased risk for type 1 diabetes.
Diabetes 67, 2329-2336 (2018)
Schaefer-Graf, U.* ; Laubner, K.* ; Hummel, S. ; Gembruch, U.* ; Groten, T.* ; Kainer, F.* ; Grieshop, M.* ; Bancher-Todesca, D.* ; Cervar-Zivakovic, M.* ; Hoesli, I.* ; Kaltheuner, M.* ; Gellner, R.* ; Kautzky-Willer, A.* ; Buehrer, C.* ; Patchev, V.* ; Nothacker, M.*
Gestational diabetes mellitus (GDM), diagnosis, therapy and follow-up.
Diabetol. Stoffwechs. 13, S174-S184 (2018)
Schäfer-Graf, U.M.* ; Gembruch, U.* ; Kainer, F.* ; Groten, T.* ; Hummel, S. ; Hösli, I.* ; Grieshop, M.* ; Kaltheuner, M.* ; Bührer, C.* ; Kautzky-Willer, A.* ; Laubner, K.* ; Bancher-Todesca, D.*
Gestational Diabetes Mellitus (GDM) - Diagnosis, Treatment and Follow-Up. Guideline of the DDG and DGGG (S3 Level, AWMF Registry Number 057/008, February 2018).
Geburtsh. u. Frauenheilk. 78, 1219-1231 (2018)
Schäfer-Graf, U.M.* ; Laubner, K.* ; Hummel, S. ; Gembruch, U.* ; Groten, T.* ; Kainer, F.* ; Grieshop, M.* ; Bancher-Todesca, D.* ; Cervar-Zivakovic, M.* ; Hösli, I.* ; Kaltheuner, M.* ; Gellner, R.* ; Kautzky-Willer, A.* ; Bührer, C.* ; Patchev, V.* ; Nothacker, M.*
Erratum: Gestationsdiabetes mellitus (GDM), Diagnostik, Therapie und Nachsorge:: Praxisempfehlung - Kurzfassung der S3-Leitlinie (AWMF-Registernummer: 057-008) (Diabetologie und Stoffwechsel (2018) 13:Suppl 2 (S174-S184) DOI: 10.1055/a-0598-3468).
Diabetol. Stoffwechs. 13, E1 (2018)
Serr, I. ; Scherm, M.G. ; Zahm, A.M.* ; Schug, J.* ; Flynn, V.K. ; Hippich, M.* ; Kälin, S.* ; Becker, M. ; Achenbach, P.* ; Nikolaev, A.* ; Gerlach, K.* ; Liebsch, N.* ; Loretz, B.* ; Lehr, C.M.* ; Kirchner, B.* ; Spornraft, M.* ; Haase, B.* ; Segars, J.* ; Küper, C.* ; Palmisano, R.* ; Waisman, A.* ; Willis, R.A.* ; Kim, W.U.* ; Weigmann, B.* ; Kaestner, K.H.* ; Ziegler, A.G.* ; Daniel, C.
A miRNA181a/NFAT5 axis links impaired T cell tolerance induction with autoimmune type 1 diabetes.
Sci. Transl. Med. 10:eaag1782 (2018)
Serr, I. ; Daniel, C.*
Prävention von Typ-1-Diabetes: Zukünftige neue Behandlungsformen.
Diabetologe 14, 257-261 (2018)
Serr, I. ; Daniel, C.
Regulation of T follicular helper cells in islet autoimmunity.
Front. Immunol. 9:1729 (2018)
Sharma, A.* ; Liu, X.* ; Hadley, D.* ; Hagopian, W.* ; Chen, W.M.* ; Onengut-Gumuscu, S.* ; Törn, C.* ; Steck, A.K.* ; Frohnert, B.I.* ; Rewers, M.* ; Ziegler, A.-G. ; Lernmark, A.* ; Toppari, J.* ; Krischer, J.P.* ; Akolkar, B.* ; Rich, S.S.* ; She, J.X.* ; TEDDY Study Group (The Teddy Study Group*)
Identification of non-HLA genes associated with development of islet autoimmunity and type 1 diabetes in the prospective TEDDY cohort.
J. Autoimmun. 89, 90-100 (2018)
Sioofy-Khojine, A.* ; Oikarinen, S.* ; Honkanen, H.* ; Huhtala, H.* ; Lehtonen, J.P.* ; Briese, T.* ; Hyoty, H.* ; TEDDY Study Group (Ziegler, A.-G. ; Beyerlein, A. ; Hummel, M. ; Hummel, S. ; Knopff, A. ; Scholz, M. ; Stock, J. ; Warncke, K. ; Wendel, L. ; Winkler, C.)
Molecular epidemiology of enteroviruses in young children at increased risk of type 1 diabetes.
PLoS ONE 13:e0201959 (2018)
Smith, L.B.* ; Liu, X.* ; Johnson, S.B.* ; Tamura, R.* ; Elding Larsson, H.* ; Ahmed, S.* ; Veijola, R.* ; Haller, M.J.* ; Akolkar, B.* ; Hagopian, W.A.* ; Rewers, M.J.* ; Krischer, J.* ; Steck, A.K.* ; TEDDY Study Group (Ziegler, A.-G. ; Beyerlein, A. ; Hummel, M. ; Hummel, S. ; Janz, N. ; Knopff, A. ; Peplow, C. ; Roth, R. ; Scholz, M. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Wendel, L. ; Winkler, C.)
Family adjustment to diabetes diagnosis in children: Can participation in a study on type 1 diabetes genetic risk be helpful?
Pediatr. Diabetes 19, 1025-1033 (2018)
Stanfill, B.A.* ; Nakayasu, E.S.* ; Bramer, L.M.* ; Thompson, A.M.* ; Ansong, C.K.* ; Clauss, T.R.* ; Gritsenko, M.A.* ; Monroe, M.E.* ; Moore, R.J.* ; Orton, D.J.* ; Piehowski, P.D.* ; Schepmoes, A.A.* ; Smith, R.D.* ; Webb-Robertson, B.M.* ; Metz, T.O.* ; TEDDY Study Group (Ziegler, A.-G. ; Beyerlein, A. ; Hummel, M. ; Hummel, S. ; Knopff, A. ; Roth, R. ; Scholz, M. ; Stock, J. ; Warncke, K. ; Wendel, L. ; Winkler, C.)
Quality control analysis in real-time (QC-ART): A tool for real-time quality control assessment of mass spectrometry-based proteomics data.
Mol. Cell. Proteomics 17, 1824-1836 (2018)
Stewart, C.J.* ; Ajami, N.J.* ; O’Brien, J.L.* ; Hutchinson, D.S.* ; Smith, D.P.* ; Wong, M.C.* ; Ross, M.C.* ; Lloyd, R.E.* ; Doddapaneni, H.V.* ; Metcalf, G.A.* ; Muzny, D.* ; Gibbs, R.A.* ; Vatanen, T.* ; Huttenhower, C.* ; Xavier, R.J.* ; Rewers, M.* ; Hagopian, W.* ; Toppari, J.* ; Ziegler, A.-G. ; She, J.X.* ; Akolkar, B.* ; Lernmark, A.* ; Hyoty, H.* ; Vehik, K.* ; Krischer, J.P.* ; Petrosino, J.F.*
Temporal development of the gut microbiome in early childhood from the TEDDY study.
Nature 562, 583-588 (2018)
Tavira, B.* ; Barcenilla, H.* ; Wahlberg, J.* ; Achenbach, P. ; Ludvigsson, J.* ; Casas, R.*
Intralymphatic glutamic acid decarboxylase (GAD)-alum administration induced Th2-like specific immunomodulation in responder patients: a pilot clinical trial in type 1 diabetes.
J. Diabetes Res. 2018, 9391845 (2018)
Uusitalo, U.* ; Lee, H.S.* ; Aronsson, C.A.* ; Vehik, K.* ; Yang, J.A.* ; TEDDY Study Group (Hummel, S. ; Ziegler, A.-G. ; Teddy Study Group*) ; Silvis, K.* ; Lernmark, A.* ; Rewers, M.* ; Hagopian, W.* ; She, J.X.* ; Simell, O.* ; Toppari, J.* ; Akolkar, B.* ; Krischer, J.* ; Virtanen, S.M.* ; Norris, J.M.*
Early infant diet and islet autoimmunity in the TEDDY Study.
Diabetes Care 41, 522-530 (2018)
Vatanen, T.* ; Franzosa, E.A.* ; Schwager, R.* ; Tripathi, S.* ; Arthur, T.D.* ; Vehik, K.* ; Lernmark, Å.* ; Hagopian, W.A.* ; Rewers, M.J.* ; She, J.X.* ; Toppari, J.* ; Ziegler, A.-G. ; Akolkar, B.* ; Krischer, J.P.* ; Stewart, C.J.* ; Ajami, N.J.* ; Petrosino, J.F.* ; Gevers, D.* ; Lähdesmäki, H.* ; Vlamakis, H.* ; Huttenhower, C.* ; Xavier, R.J.*
The human gut microbiome in early-onset type 1 diabetes from the TEDDY study.
Nature 562, 589-594 (2018)
Warncke, K.* ; Flores, D.* ; Heinrich, M. ; Aydin, S.E. ; Burdach, S.*
Behandlung des Typ-1-Diabetes im Frühstadium: eine Kasuistik.
Diabetologe 14, 231-233 (2018)
Winkler, C. ; Kick, K.* ; Haupt, F. ; Assfalg, R.
Früherkennung des Typ-1-Diabetes in der Fr1da-Studie: Diagnosestellung im asymptomatischen Stadium.
Diabetologe 14, 214-220 (2018)
Winkler, C. ; Ziegler, A.-G.
Neue Studie zur Prävention von Typ-1-Diabetes.
Diabetes akt. 16, 52-54 (2018)
Wolf, S.* ; Hoffmann, V. ; Habicht, A.* ; Kauke, T.* ; Bucher, J.B.* ; Schoenberg, M.H.* ; Werner, J.* ; Guba, M.* ; Andrassy, J.*
Effects of mTOR-Is on malignancy and survival following renal transplantation: A systematic review and meta-analysis of randomized trials with a minimum follow-up of 24 months.
PLoS ONE 13:e0194975 (2018)
Wolf, S.* ; Hoffmann, V. ; Habicht, A.* ; Kauke, T.* ; Bucher, J.B.* ; Schoenberg, M.H.* ; Werner, J.* ; Guba, M.* ; Andrassy, J.*
Effects of MTOR-IS on malignancy and survival following renal transplantation: A systematic review and meta-analysis of randomized trials with a minimum follow-up of 24 months.
Transpl. Int. 31, 32-32 (2018)
Wyatt, R.C.* ; Brigatti, C.* ; Liberati, D.* ; Grace, S.L.* ; Gillard, B.T.* ; Long, A.E.* ; Marzinotto, I.* ; Shoemark, D.* ; Chandler, K.A.* ; Achenbach, P. ; Gillespie, K.M.* ; Piemonti, L.* ; Lampasona, V.* ; Williams, A.J.K.*
The first 142 amino acids of glutamate decarboxylase do not contribute to epitopes recognized by autoantibodies associated with Type 1 diabetes.
Diabetic Med. 35, 954-963 (2018)
Ziegler, A.-G. ; Ohli, J. ; Hoefs, T. ; Aydin, S.E. ; Falk, C. ; Gross, J.
Früherkennung und Primärprävention des Typ-1-Diabetes: „Global Platform for the Prevention of Autoimmune Diabetes“ (GPPAD).
Diabetologe 14, 240-244 (2018)
Zissler, U.M. ; Ulrich, M. ; Jakwerth, C.A. ; Bahmer, T.* ; Weckmann, M.* ; Schmidt-Weber, C.B. ; Chaker, A.M.*
Potential of upper airway mediators as biomarkers for asthmatic lung.
Allergy 73, 200-200 (2018)
Becker, M. ; Levings, M.K.* ; Daniel, C.
Adipose-tissue regulatory T cells: Critical players in adipose-immune crosstalk.
Eur. J. Immunol. 47, 1867-1874 (2017)
Beyerlein, A. ; Wehweck, F. ; Ziegler, A.-G. ; Pflüger, M.
Miscalculation and errors in numbers reported in table.
JAMA Pediatr. 171, 93 (2017)
Beyerlein, A. ; Strobl, A.N.* ; Winkler, C. ; Carpus, M. ; Knopff, A. ; Donnachie, E.* ; Ankerst, D.P.* ; Ziegler, A.-G.
Vaccinations in early life are not associated with development of islet autoimmunity in type 1 diabetes high-risk children: Results from prospective cohort data.
Vaccine 35, 1735-1741 (2017)
TEDDY Study Group (Beyerlein, A. ; Winkler, C. ; Ziegler, A.-G. ; Hummel, S.) ; Uusitalo, U.M.* ; Virtanen, S.M.* ; Vehik, K.* ; Yang, J.* ; Kersting, M.* ; Koletzko, S.* ; Schatz, D.* ; Aronsson, C.A.* ; Elding Larsson, H.* ; Krischer, J.P.* ; Norris, J.M.*
Intake of energy and protein is associated with overweight risk at age 5.5 years: Results from the prospective TEDDY study.
Obesity 25, 1435-1441 (2017)
Beyerlein, A. ; Donnachie, E.* ; Ziegler, A.-G.
Infections in early Life and development of celiac disease.
Am. J. Epidemiol. 186, 1277-1280 (2017)
Bonifacio, E.* ; Mathieu, C.* ; Nepom, G.T.* ; Ziegler, A.-G. ; Anhalt, H.* ; Haller, M.J.* ; Harrison, L.C.* ; Hebrok, M.* ; Kushner, J.A.* ; Norris, J.M.* ; Peakman, M.* ; Powers, A.C.* ; Todd, J.A.* ; Atkinson, M.A.*
Rebranding asymptomatic type 1 diabetes: The case for autoimmune beta cell disorder as a pathological and diagnostic entity.
Diabetologia 60, 35-38 (2017)
Dandona, P.* ; Mathieu, C.* ; Phillip, M.* ; Hansen, L.* ; Griffen, S.C.* ; Tschöpe, D.* ; Thorén, F.* ; Xu, J.* ; Langkilde, A.M.* ; DEPICT-1 Investigators (Ziegler, A.-G.)
Efficacy and safety of dapagliflozin in patients with inadequately controlled type 1 diabetes (DEPICT-1): 24 week results from a multicentre, double-blind, phase 3, randomised controlled trial.
Lancet Diabet. Endocrinol. 5, 864-876 (2017)
Daniel, C. ; Weigmann, B.* ; von Boehmer, H.*
Reply to "Tolerogenic insulin peptide therapy precipitates type 1 diabetes".
J. Exp. Med. 214, 2157-2159 (2017)
Elding Larsson, H.* ; Lynch, K.F.* ; Lönnrot, M.* ; Haller, M.J.* ; Lernmark, Å.* ; Hagopian, W.A.* ; She, J.X.* ; Simell, O.* ; Toppari, J.* ; Ziegler, A.-G. ; Akolkar, B.* ; Krischer, J.P.* ; Rewers, M.J.* ; Hyöty, H.*
Pandemrix® vaccination is not associated with increased risk of islet autoimmunity or type 1 diabetes in the TEDDY study children.
Diabetologia 61, 193–202 (2017)
Fuchs, Y.F. ; Eugster, A.* ; Dietz, S. ; Sebelefsky, C. ; Kühn, D.* ; Wilhelm, C.* ; Lindner, A. ; Gavrisan, A.* ; Knoop, J. ; Dahl, A.* ; Ziegler, A.-G. ; Bonifacio, E.
CD8+ T cells specific for the islet autoantigen IGRP are restricted in their T cell receptor chain usage.
Sci. Rep. 7:44661 (2017)
Füchtenbusch, M.
Mischformen und Überlappung des Typ-1- und des Typ-2-Diabetes. Limitationen individueller Therapieoptionen durch die bestehende Disease-Management-Programm-Systematik.  
Diabetologe 13, 244-247 (2017)
Goerdes, L.* ; Achenbach, P. ; Roden, M.* ; Muessig, K.*
Eine seltene Ursache für eine hyperinsulinämische Hypoglykämie.
Diabetol. Stoffwechs. 12, 184-185 (2017)
Hagopian, W.* ; Lee, H.S.* ; Liu, E.* ; Rewers, M.* ; She, J.X.* ; Ziegler, A.-G. ; Lernmark, A.* ; Toppari, J.* ; Rich, S.S.* ; Krischer, J.P.* ; Erlich, H.* ; Akolkar, B.* ; Agardh, D.*
Co-occurrence of type 1 diabetes and celiac disease autoimmunity.
Pediatrics 140, DOI: 10.1542/peds.2017-1305 (2017)
Heninger, A.K.* ; Jergens, S. ; Wilhelm, C. ; Beyerlein, A. ; Ziegler, A.-G. ; Bonifacio, E.
A divergent population of autoantigen-responsive CD4+ T cells in infants prior to β cell autoimmunity.
Sci. Transl. Med. 9:eaaf8848 (2017)
Hommel, A.* ; Haupt, F. ; Delivani, P.* ; Winkler, C. ; Stopsack, M.* ; Wimberger, P.* ; Nitzsche, K.* ; Heinke, S.* ; Naeke, A.* ; Ceglarek, U.* ; Thiery, J.* ; Bergert, R.* ; Stadthaus, D.* ; Groeger, K.* ; Heubner, G.* ; Schramm, U.* ; Dziambor, U.* ; Zirkel, A.* ; Kiess, W.* ; Mueller, I.* ; Lange, K.* ; Berner, R.* ; Bonifacio, E.* ; Ziegler, A.-G.
Screening for type 1 diabetes risk in newborns: The Freder1k pilot study in Saxony.
Horm. Metab. Res. 50, 44-49 (2017)
TEDDY Study Group (Hummel, S. ; Beyerlein, A. ; Ziegler, A.-G.) ; Tamura, R.* ; Uusitalo, U.* ; Aronsson, C.A.* ; Yang, J.* ; Riikonen, A.* ; Lernmark, A.* ; Rewers, M.J.* ; Hagopian, W.A.* ; She, J.-X.* ; Simell, O.G.* ; Toppari, J.* ; Akolkar, B* ; Krischer, J.P.* ; Virtanen, S.M.* ; Norris, J.M.*
First infant formula type and risk of islet autoimmunity in the environmental determinants of diabetes in the young (TEDDY) study.
Diabetes Care 40, 398-404 (2017)
Johnson, S.B.* ; Lynch, K.F.* ; TEDDY Study Group (Roth, R.) ; Schatz, D.*
My child is islet autoantibody positive: Impact on parental anxiety.
Diabetes Care 40, 1167-1172 (2017)
Joslowski, G. ; Aronsson, C.A.* ; Ahonen, S.* ; Butterworth, M.* ; Rautanen, J.* ; Norris, J.M.* ; Virtanen, S.M.* ; Uusitalo, U.*
Development of a harmonized food grouping system for between-country comparisons in the TEDDY Study.
J. Food Compos. Anal. 63, 79-88 (2017)
Kälin, S. ; Becker, M. ; Ott, V. ; Serr, I. ; Hosp, F.* ; Mollah, M.M.H. ; Keipert, S. ; Lamp, D. ; Rohner-Jeanrenaud, F.* ; Flynn, V.K. ; Scherm, M.G. ; Nascimento, L.F.R. ; Gerlach, K.* ; Popp, V.* ; Dietzen, S.* ; Bopp, T.* ; Krishnamurthy, P.* ; Kaplan, M.H.* ; Serrano, M.* ; Woods, S.C.* ; Tripal, P.* ; Palmisano, R.* ; Jastroch, M. ; Blüher, M.* ; Wolfrum, C.* ; Weigmann, B.* ; Ziegler, A.-G. ; Mann, M.* ; Tschöp, M.H. ; Daniel, C.
A Stat6/Pten axis links regulatory T cells with adipose tissue function.
Cell Metab. 26, 475-492.e7 (2017)
Kemppainen, K.M.* ; Lynch, K.F.* ; Liu, E.* ; Lönnrot, M.* ; Simell, V.* ; Briese, T.* ; Koletzko, S.* ; Hagopian, W.* ; Rewers, M.* ; She, J.* ; Simell, O.* ; Toppari, J.* ; Ziegler, A.-G. ; Akolkar, B.* ; Krischer, J.P.* ; Lernmark, A.* ; Hyoty, H.* ; Triplett, E.W.* ; Agardh, D.*
Factors that increase risk of celiac disease autoimmunity after a gastrointestinal infection in early life.
Clin. Gastroenterol. Hepatol. 15, 694-702 (2017)
Kemppainen, K.M.* ; Vehik, K.* ; Lynch, K.F.* ; Larsson, H.E.* ; Canepa, R.J.* ; Simell, V.* ; Koletzko, S.* ; Liu, E.* ; Simell, O.G.* ; Toppari, J.* ; Ziegler, A.-G. ; Rewers, M.J.* ; Lernmark, A.* ; Hagopian, W.A.* ; She, J.* ; Akolkar, B.* ; Schatz, D.A.* ; Atkinson, M.A.* ; Blaser, M.J.* ; Krischer, J.P.* ; Hyoety, H.* ; Agardh, D.* ; Triplett, E.W.*
Association between early-life antibiotic use and the risk of islet or celiac disease autoimmunity.
JAMA Pediatr. 171, 1217-1225 (2017)
Knoop, J. ; Gavrisan, A. ; Kuehn, D.* ; Reinhardt, J.M.* ; Heinrich, M. ; Hippich, M. ; Eugster, A.* ; Ockert, C.* ; Ziegler, A.-G. ; Bonifacio, E.*
GM-CSF producing autoreactive CD4(+) T cells in type 1 diabetes.
Clin. Immunol. 188, 23-30 (2017)
Köhler, M. ; Umlauf, N.* ; Beyerlein, A. ; Winkler, C. ; Ziegler, A.-G. ; Greven, S.*
Flexible Bayesian additive joint models with an application to type 1 diabetes research.
Biom. J. 59, 1144-1165 (2017)
Köhler, M. ; TEDDY Study Group (Beyerlein, A. ; Ziegler, A.-G. ; Hummel, M. ; Hummel, S. ; Janz, N. ; Knopff, A. ; Peplow, C. ; Roth, R. ; Scholz, M. ; Stock, J. ; Warncke, K. ; Wendel, L. ; Winkler, C.) ; Vehik, K.* ; Greven, S.* ; Umlauf, N.* ; Lernmark, Å.* ; Hagopian, W.A.* ; Rewers, M.* ; She, J.X.* ; Toppari, J.* ; Akolkar, B.* ; Krischer, J.P.* ; Bonifacio, E.*
Joint modeling of longitudinal autoantibody patterns and progression to type 1 diabetes: Results from the TEDDY study.
Acta Diabetol. 54, 1009–1017 (2017)
Köhler, M.
Flexible Bayesian joint models for longitudinal biomarkers and time-to-event outcomes with applications to type 1 diabetes research.
München, Ludwig-Maximilians-Universität, Fakultät für Mathematik, Informatik und Statistik, Diss., 2017, 166 S.
Koletzko, S.* ; Lee, H.S.* ; TEDDY Study Group (Beyerlein, A. ; Hummel, M. ; Ziegler, A.-G. ; Hummel, S. ; Janz, N. ; Knopff, A. ; Peplow, C. ; Roth, R. ; Scholz, M. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Wendel, L. ; Winkler, C.) ; Aronsson, C.A.* ; Liu, E.* ; Simell, V.* ; Kurppa, K.* ; Lernmark, A.* ; Hagopian, W.* ; Rewers, M* ; She, J.X.* ; Simell, O* ; Toppari, J.* ; Krischer, J* ; Agardh, D.*
Cesarean section on the risk of celiac disease in the offspring: The Teddy Study.
J. Pediatr. Gastroenterol. Nutr. 66, 417-424 (2017)
Krischer, J.P.* ; Lynch, K.F.* ; Lernmark, A.* ; Hagopian, W.A.* ; Rewers, M.J.* ; She, J.X.* ; Toppari, J.* ; TEDDY Study Group (Ziegler, A.-G.) ; Akolkar, B.*
Genetic and environmental interactions modify the risk of diabetes-related autoimmunity by 6 years of age: The TEDDY Study.
Diabetes Care 40, 1194-1202 (2017)
Krischer, J.P.* ; Liu, X.* ; Lernmark, A.* ; Hagopian, W.A.* ; Rewers, M.J.* ; She, J.X.* ; Toppari, J.* ; Ziegler, A.-G. ; Akolkar, B.* ; TEDDY Study Group (Ziegler, A.-G. ; Beyerlein, A. ; Hummel, M. ; Hummel, S. ; Janz, N. ; Knopff, A. ; Peplow, C. ; Roth, R. ; Scholz, M. ; Stock, J. ; Warncke, K. ; Wendel, L. ; Winkler, C.)
The influence of type 1 diabetes genetic susceptibility regions, age, sex, and family history to the progression from multiple autoantibodies to type 1 diabetes: A TEDDY Study Report.
Diabetes 66, 3122-3129 (2017)
Lepper, M.F. ; Ohmayer, U. ; von Toerne, C.* ; Ziegler, A.-G. ; Hauck, S.M.
The proteomic landscape of patient-derived CD4+ T cells in recent-onset type 1 diabetes.
In: (Proteomic Forum 2017, 2-5 April 2017, Potsdam). 2017. 119-120
Lepper, M.F. ; Ohmayer, U. ; von Toerne, C. ; Maison, N. ; Ziegler, A.-G. ; Hauck, S.M.
Proteomic landscape of patient-derived CD4+T cells in recent-onset type 1 diabetes.
J. Proteome Res. 17, 618-634 (2017)
Lönnrot, M.* ; Lynch, K.F.* ; Elding Larsson, H.* ; Lernmark, Å.* ; Rewers, M.J.* ; Törn, C.* ; Burkhardt, B.R.* ; Briese, T.* ; Hagopian, W.A.* ; She, J.X.* ; Simell, O.G.* ; Toppari, J.* ; TEDDY Study Group (Ziegler, A.-G. ; Beyerlein, A. ; Hummel, M. ; Hummel, S. ; Janz, N. ; Knopff, A. ; Peplow, C. ; Roth, R. ; Scholz, M. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Wendel, L. ; Winkler, C.) ; Akolkar, B.* ; Krischer, J.P.* ; Hyöty, H.*
Respiratory infections are temporally associated with initiation of type 1 diabetes autoimmunity: The TEDDY study.
Diabetologia 60, 1931-1940 (2017)
Lönnrot, M.* ; Lynch, K.F.* ; Elding Larsson, H.* ; Lernmark, Å.* ; Rewers, M.J.* ; Törn, C.* ; Burkhardt, B.R.* ; Briese, T.* ; Hagopian, W.A.* ; She, J.X.* ; Simell, O.G.* ; Toppari, J.* ; Ziegler, A.-G. ; Akolkar, B.* ; Krischer, J.P.* ; Hyöty, H.*
Correction to: Respiratory infections are temporally associated with initiation of type 1 diabetes autoimmunity: The TEDDY study.
Diabetologia 61, 254-254 (2017)
Lundgren, M.* ; Steed, L.J.* ; Tamura, R.* ; Jonsdottir, B.* ; Gesualdo, P.* ; Crouch, C.* ; Sjöberg, M.* ; Hansson, G.K.* ; Hagopian, W.A.* ; TEDDY Study Group (Ziegler, A.-G.) ; Rewers, M.J.* ; Lernmark, A.* ; Toppari, J.* ; She, J.X.* ; Akolkar, B.* ; Krischer, J.P.* ; Haller, M.J.* ; Elding Larsson, H.*
Analgesic antipyretic use among young children in the TEDDY study: No association with islet autoimmunity.
BMC Pediatr. 17:127 (2017)
Meyer, D.M.* ; Brei, C.* ; Stecher, L.* ; Much, D. ; Brunner, S.* ; Hauner, H.*
Cord blood and child plasma adiponectin levels in relation to childhood obesity risk and fat distribution up to 5 y.
Pediatr. Res. 81, 745-751 (2017)
Meyer, D.M.* ; Brei, C.* ; Stecher, L.* ; Much, D. ; Brunner, S.* ; Hauner, H.*
The relationship between breast milk leptin and adiponectin with child body composition from 3 to 5 years: A follow-up study.
Pediatr. Obes. 12, 1, 125-129 (2017)
Molnos, S. ; Wahl, S. ; Haid, M. ; Eekhoff, E.M.W.* ; Pool, R.* ; Floegel, A.* ; Deelen, J.* ; Much, D. ; Prehn, C. ; Breier, M. ; Draisma, H.H.* ; van Leeuwen, N.* ; Simonis-Bik, A.M.C.* ; Jonsson, A.* ; Willemsen, G.* ; Bernigau, W.* ; Wang-Sattler, R. ; Suhre, K. ; Peters, A. ; Thorand, B. ; Herder, C.* ; Rathmann, W.* ; Roden, M.* ; Gieger, C. ; Kramer, M.H.H.* ; van Heemst, D.* ; Pedersen, H.K.* ; Gudmundsdottir, V.* ; Schulze, M.B.* ; Pischon, T.* ; de Geus, E.J.C.* ; Boeing, H.* ; Boomsma, D.I.* ; Ziegler, A.-G. ; Slagboom, P.E.* ; Hummel, S. ; Beekman, M.* ; Grallert, H. ; Brunak, S.* ; McCarthy, M.I.* ; Gupta, R.* ; Pearson, E.R.* ; Adamski, J. ; 't Hart, L.M.*
Metabolite ratios as potential biomarkers for type 2 diabetes: A DIRECT study.
Diabetologia 61, 117-129 (2017)
Rodriguez-Calvo, T. ; Atkinson, M.* ; von Herrath, M.*
β-Cell mass versus function in type 1 diabetes mellitus: truth or dare?
Nat. Rev. Endocrinol. 13, 492-492 (2017)
Rodriguez-Calvo, T. ; Atkinson, M.* ; Von Herrath, M.G.*
Response to comment on Rodriguez-Calvo et al. Increase in pancreatic proinsulin and preservation of β-cell mass in autoantibody-positive donors prior to type 1 diabetes onset. diabetes 2017;66:1334-1345.
Diabetes 66, e10-e11 (2017)
Rodriguez-Calvo, T. ; Atkinson, M.* ; Von Herrath, M.G.*
Response to comment on Rodriguez-Calvo et al. Increase in pancreatic proinsulin and preservation of β-cell mass in autoantibody-positive donors prior to type 1 diabetes onset. Diabetes 2017;66:1334–1345.
Diabetes 66, e10-e11 (2017)
TEDDY Study Group (Roth, R. ; Strauss, E.) ; Baxter, J.* ; Vehik, K.* ; Hopkins, D.* ; Killian, M.* ; Gesualdo, P.* ; Melin, J.* ; Simell, B.* ; Lernmark, A.* ; Johnson, S.B.*
The feasibility of salivary sample collection in an international pediatric cohort: The the TEDDY study.
Dev. Psychobiol. 59, 658-667 (2017)
Schoen, S.* ; Jergens, S. ; Barbaresko, J.* ; Nöethlings, U.* ; Kersting, M.* ; Remer, T.* ; Stelmach-Mardas, M.* ; Ziegler, A.-G. ; Hummel, S.
Diet quality during infancy and early childhood in children with and without risk of type 1 diabetes: A DEDIPAC Study.
Nutrients 9:E48 (2017)
Smith, L.B.* ; Lynch, K.F.* ; Kurppa, K.* ; Koletzko, S. ; Krischer, J.* ; Liu, E.* ; Johnson, S.B.* ; Agardh, D.* ; TEDDY Study Group (Ziegler, A.-G. ; Beyerlein, A. ; Hummel, M. ; Hummel, S. ; Janz, N. ; Knopff, A. ; Peplow, C. ; Roth, R. ; Scholz, M. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Wendel, L. ; Winkler, C.)
Psychological manifestations of celiac disease autoimmunity in young children.
Pediatrics 139:e20162848 (2017)
Steck, A.K.* ; Larsson, H.E.* ; Liu, X.* ; Veijola, R.* ; Toppari, J.* ; Hagopian, W.A.* ; Haller, M.J.* ; Ahmed, S.* ; Akolkar, B.* ; Lernmark, A.* ; Rewers, M.J.* ; Krischer, J.P.* ; TEDDY Study Group (Ziegler, A.-G. ; Beyerlein, A. ; Bonifacio, E. ; Hummel, M. ; Hummel, S. ; Foterek, K. ; Janz, N. ; Knopff, A. ; Koletzko, S. ; Peplow, C. ; Roth, R. ; Scholz, M. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Wendel, L. ; Winkler, C.)
Residual beta-cell function in diabetes children followed and diagnosed in the TEDDY study compared to community controls.
Pediatr. Diabetes 18, 794-802 (2017)
Tamura, R.N.* ; Uusitalo, U.M.* ; Aronsson, C.A.* ; Silvis, K.* ; Riikonen, A.* ; Frank, N.* ; Joslowski, G. ; Winkler, C. ; Norris, J.M.* ; Virtanen, S.M.*
Vitamin D and probiotics supplement use in young children with genetic risk for type 1 diabetes.
Eur. J. Clin. Nutr. 71, 1449-1454 (2017)
Ulrich, M. ; Winkler, C. ; Ziegler, A.-G.
New study on the prevention of type-1-diabetes.
Geburtsh. u. Frauenheilk. 77, 1151-1153 (2017)
von Toerne, C. ; Laimighofer, M. ; Achenbach, P. ; Beyerlein, A. ; de Las Heras Gala, T. ; Krumsiek, J. ; Theis, F.J. ; Ziegler, A.-G. ; Hauck, S.M.
Peptide serum markers in islet autoantibody-positive children.
Diabetologia 60, 287-295 (2017)
Warncke, K. ; Lickert, R. ; Eitel, S. ; Gloning, K.P.* ; Bonifacio, E. ; Sedlmeier, E.-M. ; Becker, P. ; Knoop, J. ; Beyerlein, A. ; Ziegler, A.-G.
Thymus growth and fetal immune responses in diabetic pregnancies.
Horm. Metab. Res. 49, 892-898 (2017)
Yang, J.* ; Tamura, R.N.* ; Aronsson, C.A.* ; Uusitalo, U.M.* ; Lernmark, A.* ; Rewers, M.* ; Hagopian, W.A.* ; She, J.X.* ; Toppari, J.* ; TEDDY Study Group (Ziegler, A.-G. ; Beyerlein, A. ; Hummel, M. ; Hummel, S. ; Knopff, A. ; Peplow, C. ; Roth, R. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Winkler, C.) ; Akolkar, B.* ; Krischer, J.P.* ; Norris, J.M.* ; Virtanen, S.M.* ; Agardh, D.*
Maternal use of dietary supplements during pregnancy is not associated with coeliac disease in the offspring: The Environmental Determinants of Diabetes in the Young (TEDDY) study.
Br. J. Nutr. 117, 466-472 (2017)
Yassouridis, C.* ; Leisch, F.* ; Winkler, C. ; Ziegler, A.-G. ; Beyerlein, A.
Associations of growth patterns and islet autoimmunity in children with increased risk for type 1 diabetes: A functional analysis approach.
Pediatr. Diabetes 18, 103-110 (2017)
't Hart, L.M.* ; Molnos, S. ; Eekhoff, E.* ; Flogel, A.* ; Grallert, H. ; Wahl, S. ; McCarthy, M.I.* ; Gupta, R.* ; Pearson, E.R.* ; Much, D. ; Hummel, S. ; Beckman, M.* ; Adamski, J.
A metabolite ratio associates with measures of insulin secretion and altered risk of type 2 diabetes; a DIRECT study.
Diabetologia 59, S142-S143 (2016)
Amoroso, M.* ; Achenbach, P. ; Powell, M.* ; Coles, R.* ; Chlebowska, M.* ; Carr, L.* ; Furmaniak, J.* ; Scholz, M. ; Bonifacio, E.* ; Ziegler, A.-G. ; Smith, B.R.*
3 screen islet cell autoantibody ELISA: A sensitive and specific ELISA for the combined measurement of autoantibodies to GAD65, TO IA-2 and TO ZnT8.
Clin. Chim. Acta 462, 60-64 (2016)
Andrén Aronsson, C.* ; Lee, H.S.* ; Koletzko, S.* ; Uusitalo, U.* ; Yang, J.* ; Virtanen, S.M.* ; Liu, E.* ; Lernmark, A.* ; Norris, J.M.* ; Agardh, D.* ; TEDDY Study Group (Ziegler, A.-G. ; Beyerlein, A. ; Bonifacio, E. ; Hummel, M. ; Hummel, S. ; Foterek, K. ; Kersting, M. ; Knopff, A. ; Koletzko, S. ; Peplow, C. ; Roth, R. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Winkler, C.)
Effects of gluten intake on risk of celiac disease: A case-control study on a Swedish birth cohort.
Clin. Gastroenterol. Hepatol. 14, 403-409 (2016)
Ashton, M.P.* ; Eugster, A.* ; Walther, D.* ; Daehling, N.* ; Riethausen, S. ; Kuehn, D.* ; Klingel, K.* ; Beyerlein, A. ; Zillmer, S. ; Ziegler, A.-G. ; Bonifacio, E.
Incomplete immune response to coxsackie B viruses associates with early autoimmunity against insulin.
Sci. Rep. 6:32899 (2016)
Beyerlein, A. ; Markevych, I. ; Thiering, E. ; Warncke, K. ; Heinrich, J. ; Ziegler, A.-G.
Response to: Ambient air pollution is not associated with early manifestation of type 1 diabetes.
Epidemiology 27, E26-E28 (2016)
Beyerlein, A. ; Donnachie, E.* ; Jergens, S. ; Ziegler, A.-G.
Infections in early life and development of type 1 diabetes.
JAMA 315, 1899-1901 (2016)
Beyerlein, A. ; Donnachie, E.* ; Ziegler, A.-G.
Association of infection in early life and risk of developing type 1 diabetes - reply.
JAMA 316, 883-883:883 (2016)
Beyerlein, A. ; Koller, D.* ; Ziegler, A.-G. ; Lack, N.* ; Maier, W.
Does charge-free screening improve detection of gestational diabetes in women from deprived areas: A cross-sectional study.
BMC Pregnancy Childbirth 16:266 (2016)
Bohn, B.* ; Schöfl, C.* ; Zimmer, V.* ; Hummel, M. ; Heise, N.* ; Siegel, E.* ; Karges, W.* ; Riedl, M.* ; Holl, R.W.*
Achievement of treatment goals for secondary prevention of myocardial infarction or stroke in 29,325 patients with type 2 diabetes: A German/Austrian DPV-multicenter analysis.
Cardiovasc. Diabetol. 15:72 (2016)
Bohn, B.* ; Prinz, N.* ; Schoefl, C.* ; Zimmer, V.* ; Hummel, M. ; Heise, N.* ; Siegel, E.* ; Karges, W.* ; Riedl, M.* ; Holl, R.W.*
Are recommended goals for secondary prevention of myocardial infarction or stroke achieved in real life? A German/Austrian DPV analysis of 29,325 patients with type 2 diabetes.
Diabetologia 59, S550-S550 (2016)
Brei, C.* ; Stecher, L.* ; Much, D. ; Karla, M.T.* ; Amann-Gassner, U.* ; Shen, J.* ; Ganter, C.* ; Karampinos, D.C.* ; Brunner, S.* ; Hauner, H.*
Reduction of the n-6:n-3 long-chain PUFA ratio during pregnancy and lactation on offspring body composition: Follow-up results from a randomized controlled trial up to 5 y of age.
Am. J. Clin. Nutr. 103, 1472-1481 (2016)
Dalla Pozza, R.* ; Pirzer, R.* ; Beyerlein, A. ; Weberruß, H.* ; Oberhoffer, R.* ; Schmidt-Trucksäss, A.* ; Netz, H.* ; Haas, N.*
Beyond intima-media-thickness: Analysis of the carotid intima-media-roughness in a paediatric population.
Atherosclerosis 251, 164-169 (2016)
Endesfelder, D. ; Engel, M. ; Davis-Richardson, A.G.* ; Ardissone, A.N.* ; Achenbach, P. ; Hummel, S. ; Winkler, C. ; Atkinson, M.* ; Schatz, D.* ; Triplett, E.W.* ; Ziegler, A.-G. ; zu Castell, W.
Towards a functional hypothesis relating anti-islet cell autoimmunity to the dietary impact on microbial communities and butyrate production.
Microbiome 4:17 (2016)
Endesfelder, D. ; Hagen, M. ; Winkler, C. ; Haupt, F. ; Zillmer, S. ; Knopff, A. ; Bonifacio, E. ; Ziegler, A.-G. ; zu Castell, W. ; Achenbach, P.
A novel approach for the analysis of longitudinal profiles reveals delayed progression to type 1 diabetes in a subgroup of multiple-islet-autoantibody-positive children.
Diabetologia 59, 2172-2180 (2016)
Gyberg, V.* ; de Bacquer, D.* ; Kotseva, K.* ; de Backer, G.* ; Schnell, O.* ; Tuomilehto, J.* ; Wood, D.L.* ; Rydén, L.*
Time-saving screening for diabetes in patients with coronary artery disease: A report from EUROASPIRE IV.
BMJ Open 6:e013835 (2016)
Köhler, M. ; Ziegler, A.-G. ; Beyerlein, A.
Development of a simple tool to predict the risk of postpartum diabetes in women with gestational diabetes mellitus.
Acta Diabetol. 53, 433-437 (2016)
Larsson, H.E.* ; Vehik, K.* ; Haller, M.J.* ; Liu, X.* ; Akolkar, B.* ; Hagopian, W.* ; Krischer, J.* ; Lernmark, A.* ; She, J.X.* ; Simell, O.* ; Toppari, J.* ; Ziegler, A.-G. ; Rewers, M.* ; TEDDY Study Group (Beyerlein, A. ; Hummel, M. ; Hummel, S. ; Knopff, A. ; Peplow, C. ; Roth, R. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Winkler, C.)
Growth and risk for islet autoimmunity and progression to type 1 diabetes in early childhood: The Environmental Determinants of Diabetes in the Young Study.
Diabetes 65, 1988-1995 (2016)
Lernmark, B.* ; Lynch, K.* ; Baxter, J.* ; Roth, R. ; Simell, T.* ; Smith, L.* ; Swartling, U.* ; Johnson, S.B.* ; TEDDY Study Group (Ziegler, A.-G. ; Beyerlein, A. ; Bonifacio, E. ; Hummel, M. ; Hummel, S. ; Knopff, A. ; Peplow, C. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Winkler, C.)
Participant experiences in The Environmental Determinants of Diabetes in the Young study: Common reasons for withdrawing.
J. Diabetes Res. 2016:2720650 (2016)
Long, A.E.* ; Wilson, I.* ; Becker, D.J.* ; Libman, I.M.* ; Wong, F.S.* ; Steck, A.K.* ; Rewers, M.J.* ; Achenbach, P. ; Williams, A.J.K.* ; Gillespie, K.M.*
Is there regulation of the autoimmune response in slow progressors to type 1 diabetes?
Diabetic Med. 33, 76-77 (2016)
Much, D. ; Köhler, M. ; Beyerlein, A. ; Ziegler, A.-G. ; Hummel, S.
Gestationsdiabetes postpartal – Typ-2-Diabetes-Risikoabschätzung und präventive Therapie.
Diabetes akt. 14, 186-191 (2016)
Much, D. ; Beyerlein, A. ; Kindt, A. ; Krumsiek, J. ; Stückler, F. ; Rossbauer, M. ; Hofelich, A. ; Wiesenäcker, D. ; Hivner, S. ; Herbst, M. ; Römisch-Margl, W. ; Prehn, C. ; Adamski, J. ; Kastenmüller, G. ; Theis, F.J. ; Ziegler, A.-G. ; Hummel, S.
Lactation is associated with altered metabolomic signatures in women with gestational diabetes.
Diabetologia 59, 2193-2202 (2016)
Much, D. ; Beyerlein, A. ; Kindt, A. ; Krumsiek, J. ; Rossbauerl, M. ; Hofelich, A. ; Hivner, S. ; Herbst, M. ; Römisch-Margl, W. ; Prehn, C. ; Adamski, J. ; Kastenmüller, G. ; Theis, F.J. ; Ziegler, A.-G. ; Hummel, S.
Lactation is associated with altered metabolomic signatures in women with gestational diabetes.
Diabetologia 59, S187-S187 (2016)
Puff, R. ; Haupt, F.* ; Winkler, C. ; Assfalg, R. ; Achenbach, P. ; Ziegler, A.-G.
[Early diagnosis, early care - "Fr1da" screening of children for type 1 diabetes].
MMW-Fortschr. Med. 158, 65-67 (2016)
Raab, J. ; Haupt, F. ; Scholz, M. ; Matzke, C. ; Warncke, K. ; Lange, K.* ; Assfalg, R. ; Weininger, K. ; Wittich, S. ; Löbner, S. ; Beyerlein, A. ; Nennstiel-Ratzel, U.* ; Lang, M.* ; Laub, O.* ; Dunstheimer, D.* ; Bonifacio, E. ; Achenbach, P. ; Winkler, C. ; Ziegler, A.-G.
Capillary blood islet autoantibody screening for identifying pre-type 1 diabetes in the general population: Design and initial results of the Fr1da study.
BMJ Open 6:e011144 (2016)
Scherm, M.G. ; Ott, V. ; Daniel, C.
Follicular helper T cells in autoimmunity.
Curr. Diab. Rep. 16:75 (2016)
Serr, I. ; Fürst, R. ; Achenbach, P. ; Scherm, M.G. ; Gökmen, F. ; Haupt, F. ; Sedlmeier, E.-M. ; Knopff, A. ; Shultz, L.* ; Willis, R.A.* ; Ziegler, A.-G. ; Daniel, C.
Type 1 diabetes vaccine candidates promote human Foxp3+Treg induction in humanized mice.
Nat. Commun. 7:10991 (2016)
Serr, I. ; Fürst, R.W. ; Ott, V.B. ; Scherm, M.G. ; Nikolaev, A.* ; Gökmen, F. ; Kälin, S. ; Zillmer, S. ; Bunk, M. ; Weigmann, B.* ; Kunschke, N.* ; Loretz, B.* ; Lehr, C.M.* ; Kirchner, B.* ; Haase, B.* ; Pfaffl, M.W.* ; Waisman, A.* ; Willis, R.A.* ; Ziegler, A.G. ; Daniel, C.
miRNA92a targets KLF2 and the phosphatase PTEN signaling to promote human T follicular helper precursors in T1D islet autoimmunity.
Proc. Natl. Acad. Sci. U.S.A. 113, E6659-E6668 (2016)
Sharma, A.* ; Liu, X.* ; Hadley, D.* ; Hagopian, W.* ; Liu, E.* ; Chen, W.M.* ; Onengut-Gumuscu, S.* ; Simell, V.* ; Rewers, M.* ; Ziegler, A.-G. ; Lernmark, A.* ; Simell, O.* ; Toppari, J.* ; Krischer, J.P.* ; Akolkar, B.* ; Rich, S.S.* ; Agardh, D.* ; She, J.X.* ; TEDDY Study Group (Beyerlein, A. ; Hummel, M. ; Hummel, S. ; Knopff, A. ; Peplow, C. ; Roth, R. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Winkler, C.)
Identification of non-HLA genes associated with celiac disease and country-specific differences in a large, international pediatric cohort.
PLoS ONE 11:e0152476 (2016)
Swartling, U.* ; Lynch, K.* ; Smith, L.* ; Johnson, S.B.* ; TEDDY Study Group (Ziegler, A.-G. ; Beyerlein, A. ; Bonifacio, E. ; Hummel, M. ; Hummel, S. ; Foterek, K. ; Kersting, M. ; Knopff, A. ; Koletzko, S. ; Peplow, C. ; Roth, R. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Winkler, C.)
Parental estimation of their child's increased type 1 diabetes risk during the first 2 years of participation in an international observational study: Results from the TEDDY study.
J. Empir. Res. Hum. Res. Ethics 11, 106-114 (2016)
Telieps, T. ; Köhler, M. ; Treise, I. ; Förtsch, K. ; Adler, T. ; Busch, D.H.* ; Hrabě de Angelis, M. ; Verschoor, A.* ; Adler, K. ; Bonifacio, E. ; Ziegler, A.-G.
Longitudinal frequencies of blood leukocyte sub-populations differ between NOD and NOR mice, but do not predict diabetes in NOD mice.
J. Diabetes Res. 2016:4208156 (2016)
Törn, C.* ; Liu, X.* ; Hagopian, W.* ; Lernmark, A.* ; Simell, O.* ; Rewers, M.* ; Ziegler, A.-G. ; Schatz, D.* ; Akolkar, B.* ; Onengut-Gumuscu, S.* ; Chen, W.M.* ; Toppari, J.* ; Mykkänen, J.* ; Ilonen, J.* ; Rich, S.S.* ; She, J.X.* ; Sharma, A.* ; Steck, A.* ; Krischer, J.* ; TEDDY Study Group (Hummel, M. ; Hummel, S. ; Knopff, A. ; Peplow, C. ; Roth, R. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Winkler, C.)
Complement gene variants in relation to autoantibodies to beta cell specific antigens and type 1 diabetes in the TEDDY study.
Sci. Rep. 6:27887 (2016)
Uusitalo, U.* ; Liu, X.* ; Yang, J.* ; Aronsson, C.A.* ; Hummel, S. ; Butterworth, M.* ; Lernmark, A.* ; Rewers, M.* ; Hagopian, W.* ; She, J.X.* ; Simell, O.* ; Toppari, J.* ; Ziegler, A.-G. ; Akolkar, B.* ; Krischer, J.* ; Norris, J.M.* ; Virtanen, S.M.* ; TEDDY Study Group
Association of early exposure of probiotics and islet autoimmunity in the TEDDY study.
JAMA Pediatr. 170, 20-28 (2016)
Vehik, K.* ; Lynch, K.F.* ; Schatz, D.A.* ; Akolkar, B.* ; Hagopian, W.* ; Rewers, M.* ; She, J.X.* ; Simell, O.* ; Toppari, J.* ; Ziegler, A.-G. ; Lernmark, A.* ; Bonifacio, E.* ; Krischer, J.P.* ; TEDDY Study Group (Beyerlein, A. ; Hummel, M. ; Hummel, S. ; Janz, N. ; Knopff, A. ; Peplow, C. ; Roth, R. ; Scholz, M. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Wendel, L. ; Winkler, C.)
Reversion of β-cell autoimmunity changes risk of type 1 diabetes: TEDDY study.
Diabetes Care 39, 1535-1542 (2016)
Walther, D.* ; Eugster, A.* ; Jergens, S. ; Gavrisan, A.* ; Weinzierl, C. ; Telieps, T. ; Winkler, C. ; Ziegler, A.-G. ; Bonifacio, E.*
Tetraspanin 7 autoantibodies in type 1 diabetes.
Diabetologia 59, 1973-1976 (2016)
Warncke, K. ; Liptay, S.* ; Fröhlich-Reiterer, E.* ; Scheuing, N.* ; Schebek, M.* ; Wolf, J.* ; Rohrer, T.R.* ; Meissner, T.* ; Holl, R.W.*
Vascular risk factors in children, adolescents, and young adults with type 1 diabetes complicated by celiac disease: Results from the DPV initiative.
Pediatr. Diabetes 17, 191-198 (2016)
Yang, J.* ; Lynch, K.F.* ; Uusitalo, U.M.* ; Foterek, K.* ; Hummel, S. ; Silvis, K.* ; Andrén Aronsson, C.* ; Riikonen, A.* ; Rewers, M.* ; She, J.X.* ; Ziegler, A.-G. ; Simell, O.G.* ; Toppari, J.* ; Hagopian, W.A.* ; Lernmark, A.* ; Akolkar, B.* ; Krischer, J.P.* ; Norris, J.M.* ; Virtanen, S.M.* ; Johnson, S.B.* ; TEDDY Study Group (Beyerlein, A. ; Hummel, M. ; Knopff, A. ; Peplow, C. ; Roth, R. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Winkler, C.)
Factors associated with longitudinal food record compliance in a paediatric cohort study.
Public Health Nutr. 19, 804-813 (2016)
Ziegler, A.-G. ; Danne, T.* ; Dunger, D.B.* ; Berner, R.* ; Puff, R.* ; Kiess, W.* ; Agiostratidou, G.* ; Todd, J.A.* ; Bonifacio, E.*
Primary prevention of beta-cell autoimmunity and type 1 diabetes - the Global Platform for the Prevention of Autoimmune Diabetes (GPPAD) perspectives.
Mol. Metab. 5, 255-262 (2016)
Ziegler, A.-G. ; Haupt, F. ; Scholz, M. ; Weininger, K. ; Wittich, S. ; Löbner, S. ; Matzke, C. ; Gezginci, C. ; Riethausen, S. ; Beyerlein, A. ; Zillmer, S. ; Amoroso, M.* ; Coles, R.* ; Powell, M.* ; Furmaniak, J.* ; Rees Smith, B.* ; Winkler, C. ; Bonifacio, E. ; Achenbach, P.
3 screen ELISA for high-throughput detection of beta cell autoantibodies in capillary blood.
Diabetes Technol. Ther. 18, 687-693 (2016)
Ziegler, A.-G.
Fr1da-insulin-intervention study.Treatment of beta cell-autoimmunity by antigen-desensitization.
Mon.schr. Kinderheilkd. 164, 639-641 (2016)
Ziegler, A.-G. ; Bonifacio, E.* ; Powers, A.C.* ; Todd, J.A.* ; Harrison, L.C.* ; Atkinson, M.A.*
Type 1 diabetes prevention: A goal dependent on accepting a diagnosis of an asymptomatic disease.
Diabetes 65, 3233-3239 (2016)
Zillmer, S. ; Warncke, K. ; Raab, J. ; Winkler, C. ; Haupt, F. ; Seithe, H.* ; Frank, I.* ; Nellen-Hellmuth, N.* ; Sommer, C.* ; Lange, K.* ; Achenbach, P. ; Ziegler, A.-G.
Kinder mit Frühstadium des Typ-1-Diabetes: Drei Fallberichte aus der Fr1da-Studie.
Diabetes Stoffwechs. Herz 25, 79-83 (2016)
Zillmer, S.
Integrative analysis of microRNA and mRNA expression profiles in osteosarcoma cell lines.
München, Technische Universität, Fakultät für Medizin, Diss., 2016, 123 S.
Agardh, D.* ; Lee, H.S.* ; Kurppa, K.* ; Simell, V.* ; Aronsson, C.A.* ; Jörneus, O.* ; Hummel, M. ; Liu, E.* ; Koletzko, S.* ; TEDDY Study Group (Ziegler, A.-G. ; Beyerlein, A. ; Hummel, S. ; Knopff, A. ; Peplow, C. ; Roth, R. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Winkler, C.)
Clinical features of celiac disease: A prospective birth cohort.
Pediatrics 135, 627-634 (2015)
Aloi, M.* ; Birimberg-Schwartz, L.* ; Hojsak, I.* ; Buderus, S.* ; Paerregaard, A.* ; Bronsky, J.* ; Fell, J.* ; Koletzko, S. ; Veereman, G.* ; Shaoul, R.* ; Miele, E.* ; Turner, D.* ; Russell, R.K.*
Outcomes of a large cohort of children with IBDU compared to other IBD subtypes and treatment options- a longitudinal report from the Porto pediatric IBD group of ESPGHAN.
J. Crohns Colitis 9, S177 (2015)
Aronsson, C.A.* ; Lee, H.S.* ; Liu, E.* ; Uusitalo, U.* ; Hummel, S. ; Yang, J.* ; Hummel, M. ; Rewers, M.* ; She, J.X.* ; Simell, O.* ; Toppari, J.* ; Ziegler, A.-G. ; Krischer, J.* ; Virtanen, S.M.* ; Norris, J.M.* ; Agardh, D.* ; TEDDY Study Group (Beyerlein, A. ; Knopff, A. ; Peplow, C. ; Roth, R. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Winkler, C.)
Age at gluten introduction and risk of celiac disease.
Pediatrics 135, 239-245 (2015)
Aronsson, C.A.* ; Uusitalo, U.* ; Vehik, K.* ; Yang, J.* ; Silvis, K.* ; Hummel, S. ; Virtanen, S.M.* ; Norris, J.M.* ; TEDDY Study Group (Ziegler, A.-G. ; Beyerlein, A. ; Henneberger, L. ; Hummel, M. ; Knopff, A. ; Krause, S. ; Peplow, C. ; Pflüger, M. ; Roth, R. ; Schenkel, J. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Winkler, C.)
Age at first introduction to complementary foods is associated with sociodemographic factors in children with increased genetic risk of developing type 1 diabetes.
Matern. Child Nutr. 11, 803-814 (2015)
Berrios, C.* ; Jung, J.U.* ; Primi, B.* ; Wang, M.* ; Pedamallu, C.* ; Duke, F.* ; Marcelus, C.* ; Cheng, J.* ; Garcea, R.L.* ; Meyerson, M.* ; DeCaprio, J.A.* ; TEDDY Study Group (Ziegler, A.-G. ; Beyerlein, A. ; Henneberger, L. ; Hummel, M. ; Hummel, S. ; Knopff, A. ; Krause, S. ; Peplow, C. ; Pflüger, M. ; Roth, R. ; Schenkel, J. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Winkler, C.)
Malawi polyomavirus is a prevalent human virus that interacts with known tumor suppressors.
J. Virol. 89, 857-862 (2015)
Beyerlein, A. ; Krasmann, M. ; Thiering, E. ; Kusian, D. ; Markevych, I. ; D'Orlando, O. ; Warncke, K.* ; Jochner, S.* ; Heinrich, J. ; Ziegler, A.-G.
Ambient air pollution and early manifestation of type 1 diabetes.
Epidemiology 26, e31-e32 (2015)
Beyerlein, A. ; Liu, X.* ; Uusitalo, U.M.* ; Harsunen, M.H. ; Norris, J.M.* ; Foterek, K.* ; Virtanen, S.M.* ; Rewers, M.J.* ; She, J.X.* ; Simell, O.* ; Lernmark, A.* ; Hagopian, W.* ; Akolkar, B.* ; Ziegler, A.-G. ; Krischer, J.P.* ; Hummel, S. ; TEDDY Study Group (Hummel, M. ; Knopff, A. ; Peplow, C. ; Roth, R. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Winkler, C.)
Dietary intake of soluble fiber and risk of islet autoimmunity by 5 y of age: Results from the TEDDY study.
Am. J. Clin. Nutr. 102, 345-352 (2015)
Bonifacio, E. ; Ziegler, A.-G. ; Klingensmith, G.* ; Schober, E.* ; Bingley, P.J.* ; Rottenkolber, M.* ; Theil, A.* ; Eugster, A.* ; Puff, R. ; Peplow, C. ; Buettner, F. ; Lange, K.* ; Hasford, J.* ; Achenbach, P.
Effects of high-dose oral insulin on immune responses in children at high risk for type 1 diabetes: The Pre-POINT randomized clinical trial.
JAMA 313, 1541-1549 (2015)
Bonifacio, E.
Predicting type 1 diabetes using biomarkers.
Diabetes Care 38, 989-996 (2015)
Brei, C.* ; Brunner, S.* ; Pusch, K.* ; Much, D. ; Stecher, L.* ; Amann-Gassner, U.* ; Hauner, H.*
Long-chain polyunsaturated fatty acids during pregnancy/lactation and children's body composition: 5-year follow-up data (INFAT-study).
Ann. Nutr. Metab. 67, 413 (2015)
Chmiel, R. ; Beyerlein, A. ; Knopff, A. ; Hummel, S. ; Ziegler, A.-G. ; Winkler, C.
Early infant feeding and risk of developing islet autoimmunity and type 1 diabetes.
Acta Diabetol. 52, 621-624 (2015)
Chmiel, R. ; Giannopoulou, E.Z. ; Winkler, C. ; Achenbach, P. ; Ziegler, A.-G. ; Bonifacio, E.
Progression from single to multiple islet autoantibodies often occurs soon after seroconversion: Implications for early screening.
Diabetologia 58, 411-413 (2015)
Dopico, X.C.* ; Evangelou, M.* ; Ferreira, R.C.* ; Guo, H.* ; Pekalski, M.L.* ; Smyth, D.J.* ; Cooper, N.* ; Burren, O.S.* ; Fulford, A.J.* ; Hennig, B.J.* ; Prentice, A.M.* ; Ziegler, A.-G. ; Bonifacio, E.* ; Wallace, C.* ; Todd, J.A.*
Widespread seasonal gene expression reveals annual differences in human immunity and physiology.
Nat. Commun. 6:7000 (2015)
Eugster, A.* ; Lindner, A.* ; Catani, M.* ; Heninger, A.K.* ; Dahl, A.* ; Klemroth, S.* ; Kühn, D.* ; Dietz, S.* ; Bickle, M.* ; Ziegler, A.-G. ; Bonifacio, E.
High diversity in the TCR repertoire of GAD65 autoantigen-specific human CD4+ T cells.
J. Immunol. 194, 2531-2538 (2015)
Försch, J.
Wirkung von Vitamin D3 auf die zellvermittelte Immunantwort bei der Pathogenese des Typ-1-Diabetes.
München, Technische Universität, Fakultät Wissenschaftszentrum Weihenstephan, Diss., 2015, 131 S.
Fuchs, Y.F.* ; Jainta, G.W.* ; Kühn, D.* ; Wilhelm, C.* ; Weigelt, M.* ; Karasinsky, A.* ; Upadhyaya, B.* ; Ziegler, A.-G. ; Bonifacio, E.
Vagaries of the ELISpot assay: Specific detection of antigen responsive cells requires purified CD8+ T cells and MHC class I expressing antigen presenting cell lines.
Clin. Immunol. 157, 216-225 (2015)
Giannopoulou, E.Z. ; Winkler, C. ; Chmiel, R. ; Matzke, C. ; Scholz, M. ; Beyerlein, A. ; Achenbach, P. ; Bonifacio, E. ; Ziegler, A.-G.
Islet autoantibody phenotypes and incidence in children at increased risk for type 1 diabetes.
Diabetologia 58, 2317-2323 (2015)
Giannopoulou, E.Z.
Factors that influence age of type 1 diabetes onset and beta cell function in children and adults with newly diagnosed type 1 diabetes.
München, Technische Universität, Fakultät für Medizin, Diss., 2015, 152 S.
Hadley, D.* ; Hagopian, W.* ; Liu, E.* ; She, J.X.* ; Simell, O.* ; Akolkar, B.* ; Ziegler, A.-G. ; Rewers, M.* ; Krischer, J.P.* ; Chen, W.M.* ; Onengut-Gumuscu, S.* ; Bugawan, T.L.* ; Rich, S.S.* ; Erlich, H.* ; Agardh, D.* ; TEDDY Study Group (Beyerlein, A. ; Hummel, M. ; Hummel, S. ; Knopff, A. ; Peplow, C. ; Roth, R. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Winkler, C.)
HLA-DPB1*04:01 protects genetically susceptible children from celiac disease autoimmunity in the TEDDY study.
Am. J. Gastroenterol. 110, 915-920 (2015)
Insel, R.A. ; Dunne, J.L.* ; Ziegler, A.-G.
General population screening for type 1 diabetes: Has its time come?
Curr. Opin. Endocrinol. Diabetes Obes. 22, 270-276 (2015)
Insel, R.A.* ; Dunne, J.L.* ; Atkinson, M.A.* ; Chiang, J.L.* ; Dabelea, D.* ; Gottlieb, P.A.* ; Greenbaum, C.J.* ; Herold, K.C.* ; Krischer, J.P.* ; Lernmark, A.* ; Ratner, R.E.* ; Rewers, M.J.* ; Schatz, D.A.* ; Skyler, J.S.* ; Sosenko, J.M.* ; Ziegler, A.-G.
Staging presymptomatic type 1 diabetes: A scientific statement of JDRF, the Endocrine Society, and the American Diabetes Association.
Diabetes Care 38, 1964-1974 (2015)
Johnson, S.B.* ; Lynch, K.F.* ; Baxter, J.* ; Lernmark, B.* ; Roth, R.* ; Simell, T.* ; Smith, L.* ; TEDDY Study Group (Ziegler, A.-G. ; Beyerlein, A. ; Hummel, M. ; Hummel, S. ; Knopff, A. ; Peplow, C. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Winkler, C.)
Predicting later study withdrawal in participants active in a longitudinal birth cohort study for 1 year: The TEDDY study.
J. Pediatr. Psychol., DOI: 10.1093/jpepsy/jsv092 (2015)
Kemppainen, K.M.* ; Ardissone, A.N.* ; Davis-Richardson, A.G.* ; Fagen, J.R.* ; Gano, K.A.* ; León-Novelo, L.G.* ; Vehik, K.* ; Casella, G.* ; Simell, O.* ; Ziegler, A.-G. ; Rewers, M.J.* ; Lernmark, A.* ; Hagopian, W.* ; She, J.X.* ; Krischer, J.P.* ; Akolkar, B.* ; Schatz, D.A.* ; Atkinson, M.A.* ; Triplett, E.W.* ; TEDDY Study Group (Beyerlein, A. ; Bonifacio, E. ; Hummel, M. ; Hummel, S. ; Foterek, K. ; Kersting, M. ; Knopff, A. ; Koletzko, S. ; Peplow, C. ; Roth, R. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Winkler, C.)
Early childhood gut microbiomes show strong geographic differences among subjects at high risk for type 1 diabetes.
Diabetes Care 38, 329-332 (2015)
Krischer, J.P.* ; Lynch, K.F.* ; Schatz, D.A.* ; Ilonen, J.* ; Lernmark, A.* ; Hagopian, W.A.* ; Rewers, M.J.* ; She, J.X.* ; Simell, O.G.* ; Toppari, J.* ; Ziegler, A.-G. ; Akolkar, B.* ; Bonifacio, E.* ; TEDDY Study Group (Beyerlein, A. ; Hummel, M. ; Hummel, S. ; Knopff, A. ; Peplow, C. ; Roth, R. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Winkler, C.)
The 6 year incidence of diabetes-associated autoantibodies in genetically at-risk children: The TEDDY study.
Diabetologia 58, 980-987 (2015)
Lönnrot, M.* ; Lynch, K.* ; Larsson, H.E.* ; Lernmark, A.* ; Rewers, M.* ; Hagopian, W.* ; She, J.* ; Simell, O.* ; Ziegler, A.-G. ; Akolkar, B.* ; Krischer, J.* ; Hyoty, H.* ; TEDDY Study Group (Beyerlein, A. ; Hummel, M. ; Hummel, S. ; Knopff, A. ; Peplow, C. ; Roth, R. ; Schenkel, J. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Winkler, C.)
A method for reporting and classifying acute infectious diseases in a prospective study of young children: TEDDY.
BMC Pediatr. 15:24 (2015)
Much, D. ; Jaschinski, H. ; Lack, N.* ; Hummel, S. ; Füchtenbusch, M. ; Hummel, M. ; Ziegler, A.-G. ; Beyerlein, A.
Risk stratification in women with gestational diabetes according to and beyond current WHO criteria.
Horm. Metab. Res. 48, 16-19 (2015)
Puff, R. ; D'Orlando, O. ; Heninger, A.K.* ; Kühn, D.* ; Krause, S. ; Winkler, C. ; Beyerlein, A. ; Bonifacio, E.* ; Ziegler, A.-G.
Compromised immune response in infants at risk for type 1 diabetes born by Caesarean Section.
Clin. Immunol. 160, 282–285 (2015)
Schütt, M.* ; Zimmermann, A.* ; Hood, R.* ; Hummel, M. ; Seufert, J.* ; Siegel, E.* ; Tytko, A.* ; Holl, R.W.*
Gender-specific effects of treatment with lifestyle, metformin or sulfonylurea on glycemic control and body weight: A German multicenter analysis on 9108 patients.
Exp. Clin. Endocrinol. Diabet. 65, 622-626 (2015)
Sebelefsky, C. ; Karner, D.* ; Voitl, J.* ; Klein, F.* ; Voitl, P.* ; Böck, A.*
Internet health seeking behaviour of parents attending a general paediatric outpatient clinic: A cross-sectional observational study.
J. Telemed. Telecare 21, 400-407 (2015)
Steck, A.K.* ; Vehik, K.* ; Bonifacio, E.* ; Lernmark, A.* ; Ziegler, A.-G. ; Hagopian, W.A.* ; She, J.* ; Simell, O.* ; Akolkar, B.* ; Krischer, J.* ; Schatz, D.* ; Rewers, M.J.* ; TEDDY Study Group (Beyerlein, A. ; Hummel, M. ; Hummel, S. ; Knopff, A. ; Peplow, C. ; Roth, R. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Winkler, C.)
Predictors of progression from the appearance of islet autoantibodies to early childhood diabetes: The Environmental Determinants of Diabetes in the Young (TEDDY).
Diabetes Care 38, 808-813 (2015)
Steiner, S.* ; Daniel, C. ; Fischer, A.* ; Atreya, I.* ; Hirschmann, S.* ; Waldner, M.* ; Neumann, H.* ; Neurath, M.F.* ; Atreya, R.* ; Weigmann, B.*
Cyclosporine A regulates pro-inflammatory cytokine production in ulcerative colitis.
Arch. Immunol. Ther. Exp. 63, 53-63 (2015)
Törn, C.* ; Hadley, D.* ; Lee, H.S.* ; Hagopian, W.* ; Lernmark, A.* ; Simell, O.* ; Rewers, M.* ; Ziegler, A.-G. ; Schatz, D.* ; Akolkar, B.* ; Onengut-Gumuscu, S.* ; Chen, W.M.* ; Toppari, J.* ; Mykkänen, J.* ; Ilonen, J.* ; Rich, S.S.* ; She, J.X.* ; Steck, A.K.* ; Krischer, J.* ; TEDDY Study Group (Beyerlein, A. ; Bonifacio, E. ; Hummel, M. ; Hummel, S. ; Foterek, K. ; Kersting, M. ; Knopff, A. ; Koletzko, S. ; Peplow, C. ; Roth, R. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Winkler, C.)
Role of Type 1 diabetes associated SNPs on risk of autoantibody positivity in the TEDDY study.
Diabetes 64, 1818-1829 (2015)
Uusitalo, U.* ; Lee, H.S.* ; Aronsson, C.A.* ; Yang, J.* ; Virtanen, S.M.* ; Norris, J.M.* ; Agardh, D.* ; TEDDY Study Group (Ziegler, A.-G. ; Beyerlein, A. ; Hummel, M. ; Hummel, S. ; Knopff, A. ; Peplow, C. ; Roth, R. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Winkler, C.)
Gluten consumption during late pregnancy and risk of celiac disease in the offspring: The TEDDY birth cohort.
Am. J. Clin. Nutr. 102, 1216-1221 (2015)
Weber, K.S.C. ; Raab, J. ; Haupt, F. ; Aschemeier, B.* ; Wosch, A. ; Ried, C. ; Kordonouri, O.* ; Ziegler, A.-G. ; Winkler, C.
Evaluating the diet of children at increased risk for type 1 diabetes: First results from the TEENDIAB study.
Public Health Nutr. 18, 50-58 (2015)
Williams, A.J.* ; Lampasona, V.* ; Schlosser, M.* ; Mueller, P.W.* ; Pittman, D.L.* ; Winter, W.E.* ; Akolkar, B.* ; Wyatt, R.* ; Brigatti, C.* ; Krause, S. ; Achenbach, P.
Detection of antibodies directed to the N-terminal region of GAD is dependent on assay format and contributes to differences in the specificity of GAD autoantibody assays for type 1 diabetes.
Diabetes 64, 3239-3246 (2015)
Williams, A.J.* ; Lampasona, V.* ; Wyatt, R.* ; Brigatti, C.* ; Gillespie, K.M.* ; Bingley, P.J.* ; Achenbach, P.
Reactivity to N-terminally truncated GAD65(96-585) identifies GAD autoantibodies that are more closely associated with diabetes progression in relatives of patients with type 1 diabetes.
Diabetes 64, 3247-3252 (2015)
Achenbach, P. ; Winkler, C. ; Haupt, F. ; Beyerlein, A. ; Ziegler, A.-G.
Prädisposition, frühe Stadien und Phänotypen des Typ-1-Diabetes.
Dtsch. Med. Wochenschr. 139, 1100-1104 (2014)
Achenbach, P. ; Ziegler, A.-G.
Über Phänotypen des Diabetes mellitus und deren klinische Bedeutung.
Dtsch. Med. Wochenschr. 139, 1095-1096 (2014)
Bender, C.* ; Schlosser, M.* ; Christen, U.* ; Ziegler, A.-G. ; Achenbach, P.
GAD autoantibody affinity in schoolchildren from the general population.
Diabetologia 57, 1911-1918 (2014)
Beyerlein, A. ; Kusian, D. ; Ziegler, A.-G. ; Schaffrath-Rosario, A.* ; von Kries, R.*
Classification tree analyses reveal limited potential for early targeted prevention against childhood overweight.
Obesity 22, 512–517 (2014)
Beyerlein, A. ; Thiering, E. ; Pflueger, M. ; Bidlingmaier, M.* ; Stock, J. ; Knopff, A. ; Winkler, C. ; Heinrich, J. ; Ziegler, A.-G.
Early infant growth is associated with the risk of islet autoimmunity in genetically susceptible children.
Pediatr. Diabetes 15, 534-542 (2014)
Beyerlein, A.
Quantile regression-opportunities and challenges from a user's perspective.
Am. J. Epidemiol. 180, 330-331 (2014)
Beyerlein, A. ; Chmiel, R. ; Hummel, S. ; Winkler, C. ; Bonifacio, E.* ; Ziegler, A.-G.
Timing of gluten introduction and islet autoimmunity in young children: Updated results from the BABYDIET study.
Diabetes Care 37, e194-e195 (2014)
Bonifacio, E.* ; Krumsiek, J. ; Winkler, C. ; Theis, F.J. ; Ziegler, A.-G.
A strategy to find gene combinations that identify children who progress rapidly to type 1 diabetes after islet autoantibody seroconversion.
Acta Diabetol. 51, 403-411 (2014)
Couper, J.J.* ; Haller, M.J.* ; Ziegler, A.-G. ; Knip, M.* ; Ludvigsson, J.* ; Craig, M.E.*
Phases of type 1 diabetes in children and adolescents.
Pediatr. Diabetes 15, 18-25 (2014)
Daniel, C. ; Gerlach, K.* ; Väth, M.* ; Neurath, M.F.* ; Weigmann, B.*
Nuclear factor of activated T cells - a transcription factor family as critical regulator in lung and colon cancer.
Int. J. Cancer 134, 1767-1775 (2014)
Elding Larsson, H.* ; Vehik, K.* ; Gesualdo, P.* ; Akolkar, B.* ; Hagopian, W.* ; Krischer, J.P.* ; Lernmark, A.* ; Rewers, M.* ; Simell, O.* ; She, J.-X.* ; Ziegler, A.-G. ; Haller, M.J.* ; TEDDY Study Group (Beyerlein, A. ; Bonifacio, E. ; Hummel, M. ; Hummel, S. ; Foterek, K. ; Kersting, M. ; Knopff, A. ; Koletzko, S. ; Peplow, C. ; Roth, R. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Winkler, C.)
Children followed in the TEDDY study are diagnosed with type 1 diabetes at an early stage of disease.
Pediatr. Diabetes 15, 118-126 (2014)
Endesfelder, D. ; zu Castell, W. ; Ardissone, A.* ; Davis-Richardson, A.G.* ; Achenbach, P. ; Hagen, M. ; Pflueger, M. ; Gano, K.A.* ; Fagen, J.R.* ; Drew, J.C.* ; Brown, C.T.* ; Kolaczkowski, B.* ; Atkinson, M.J. ; Schatz, D.* ; Bonifacio, E. ; Triplett, E.W.* ; Ziegler, A.-G.
Compromised gut microbiota networks in children with anti-islet cell autoimmunity.
Diabetes 63, 2006-2014 (2014)
Ferreira, R.C.* ; Guo, H.* ; Coulson, R.M.* ; Smyth, D.J.* ; Pekalski, M.L.* ; Burren, O.S.* ; Cutler, A.J.* ; Doecke, J.D.* ; Flint, S.* ; McKinney, E.F.* ; Lyons, P.A.* ; Smith, K.G.* ; Achenbach, P. ; Beyerlein, A. ; Dunger, D.B.* ; Wicker, L.S.* ; Todd, J.A.* ; Bonifacio, E.* ; Wallace, C.* ; Ziegler, A.-G.
A type I interferon transcriptional signature precedes autoimmunity in children genetically at risk of type 1 diabetes.
Diabetes 63, 2538-2550 (2014)
Fuchs, Y.F.* ; Adler, K.* ; Lindner, A.* ; Karasinsky, A.* ; Wilhelm, C.* ; Weigelt, M.* ; Balke, H. ; Förtsch, K. ; Mortler-Hildebrandt, L.F. ; Harlan, D.M.* ; Pechhold, K.* ; Ziegler, A.-G. ; Bonifacio, E.*
Igrp and insulin vaccination induce CD8+ T cell mediated autoimmune diabetes in the RIP-CD80GP mouse.
Clin. Exp. Immunol. 176, 199-206 (2014)
Giannopoulou, E.Z. ; Puff, R. ; Beyerlein, A. ; von Luettichau, I.* ; Boerschmann, H.* ; Schatz, D.* ; Atkinson, M.* ; Haller, M.J.* ; Egger, D.* ; Burdach, S.* ; Ziegler, A.-G.
Effect of a single autologous cord blood infusion on beta-cell and immune function in children with new onset type 1 diabetes: A non-randomized, controlled trial.
Pediatr. Diabetes 15, 100-109 (2014)
Hummel, S. ; Vehik, K.* ; Uusitalo, U.* ; McLeod, W.* ; Aronsson, C.A.* ; Frank, N.* ; Gesualdo, P.* ; Yang, J.* ; Norris, J.M.* ; Virtanen, S.M.* ; TEDDY Study Group (Ziegler, A.-G. ; Beyerlein, A. ; Bonifacio, E. ; Hummel, M. ; Foterek, K. ; Kersting, M. ; Knopff, A. ; Koletzko, S. ; Peplow, C. ; Roth, R. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Winkler, C.)
Infant feeding patterns in families with a diabetes history - observations from The Environmental Determinants of Diabetes in the Young (TEDDY) birth cohort study.
Public Health Nutr. 17, 2853-2862 (2014)
Johnson, S.B.* ; Lynch, K.F.* ; Lee, H.-S.* ; Smith, L.* ; Baxter, J.* ; Lernmark, B.* ; Roth, R. ; Simell, T.*
At high risk for early withdrawal: Using a cumulative risk model to increase retention in the first year of the TEDDY study.
J. Clin. Epidemiol. 67, 609-611 (2014)
Jung, N.* ; Pereira, B.* ; Nehring, I.* ; Brix, O.* ; Bernius, P.A.* ; Schroeder, S.A.* ; Kluger, G.J.* ; Koehler, T.* ; Beyerlein, A. ; Weir, S.* ; von Kries, R.* ; Narayanan, U.G.* ; Berweck, S.* ; Mall, V.*
Does hip displacement influence health-related quality of life in children with cerebral palsy?
Dev. Neurorehabil. 17, 420-425 (2014)
Jung, N.H.* ; Brix, O.* ; Bernius, P.* ; Schroeder, A.S.* ; Kluger, G.J.* ; Beyerlein, A. ; Weir, S.* ; von Kries, R.* ; Narayanan, U.G.* ; Mall, V.* ; Berweck, S.*
German translation of the caregiver priorities and child health index of life with disabilities questionnaire: Test-retest reliability and correlation with gross motor function in children with cerebral palsy.
Neuropediatrics 45, 289-293 (2014)
Krause, S. ; Landherr, U.* ; Agardh, C.-D.* ; Hausmann, S. ; Link, K.* ; Hansen, J.M.* ; Lynch, K.F.* ; Powell, M.* ; Furmaniak, J.* ; Rees-Smith, B.* ; Bonifacio, E.* ; Ziegler, A.-G. ; Lernmark, A.* ; Achenbach, P.
GAD autoantibody affinity in adult patients with latent autoimmune diabetes, the study participants of a GAD65 vaccination trial.
Diabetes Care 37, 1675-1680 (2014)
Krause, S. ; Beyerlein, A. ; Winkler, C. ; Gavrisan, A.* ; Kayser, C. ; Puff, R.* ; Bonifacio, E.* ; Ziegler, A.-G. ; Achenbach, P.
Soluble interleukin-2 receptor alpha in preclinical type 1 diabetes.
Acta Diabetol. 51, 517-518 (2014)
Krause, S.
Etablierung und Evaluierung neuer diagnostischer Marker für Typ-1-Diabetes.
Dresden, Technische Universität, Diss., 2014, 115 S.
Lee, H.S.* ; Burkhardt, B.R.* ; McLeod, W.* ; Smith, S.* ; Eberhard, C.* ; Lynch, K.* ; Hadley, D.* ; Rewers, M.* ; Simell, O.* ; She, J.X.* ; Hagopian, B.* ; Lernmark, A.* ; Akolkar, B.* ; Ziegler, A.-G. ; Krischer, J.P.* ; TEDDY Study Group (Beyerlein, A. ; Bonifacio, E. ; Hummel, M. ; Hummel, S. ; Foterek, K. ; Kersting, M. ; Knopff, A. ; Koletzko, S. ; Peplow, C. ; Roth, R. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Winkler, C.)
Biomarker discovery study design for type 1 diabetes in The Environmental Determinants of Diabetes in the Young (TEDDY) study.
Diabetes Metab. Res. Rev. 30, 424-434 (2014)
Liu, E. ; Lee, H.S.* ; Aronsson, C.A.* ; Hagopian, W.A.* ; Koletzko, S.* ; Rewers, M.J.* ; Eisenbarth, G.S.* ; Bingley, P.J.* ; Bonifacio, E. ; Simell, V.* ; Agardh, D.* ; TEDDY Study Group (Ziegler, A.-G. ; Beyerlein, A. ; Bonifacio, E. ; Hummel, M. ; Hummel, S. ; Foterek, K. ; Kersting, M. ; Knopff, A. ; Koletzko, S. ; Peplow, C. ; Roth, R. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Winkler, C.)
Risk of pediatric celiac disease according to HLA haplotype and country.
N. Engl. J. Med. 371, 42-49 (2014)
Mehnert, H.*
Diabetes mellitus - Ursachen, Epidemiologie, Behandlungsmöglichkeiten und Folgeschäden der Erkrankung.
Jubiläumskongress der Deutschen Diabetes Gesellschaft, May 2014, Munich, Germany. Neuherberg: Helmholtz Zentrum München GmbH, 2014. 24 S.
Much, D. ; Beyerlein, A. ; Roßbauer, M. ; Hummel, S. ; Ziegler, A.-G.
Beneficial effects of breastfeeding in women with gestational diabetes mellitus.
Mol. Metab. 3, 284-292 (2014)
Raab, J. ; Giannopoulou, E.Z. ; Schneider, S. ; Warncke, K. ; Krasmann, M. ; Winkler, C. ; Ziegler, A.-G.
Prevalence of vitamin D deficiency in pre-type 1 diabetes and its association with disease progression.
Diabetologia 57, 902-908 (2014)
Raab, J.
Die Rolle von Vitamin D und Insulinresistenz in der Pathogenese des Typ-1-Diabetes.
München, Technische Universität, Fakultät Wissenschaftszentrum Weihenstephan, Diss., 2014, 123 S.
Roth, R. ; Lynch, K.* ; Lernmark, B.* ; Baxter, J.* ; Simell, T.* ; Smith, L.* ; Swartling, U.* ; Ziegler, A.-G. ; Johnson, S.B.* ; TEDDY Study Group (Beyerlein, A. ; Bonifacio, E. ; Hummel, M. ; Hummel, S. ; Foterek, K. ; Kersting, M. ; Knopff, A. ; Koletzko, S. ; Peplow, C. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Winkler, C.)
Maternal anxiety about a child's diabetes risk in the TEDDY study: The potential role of life stress, postpartum depression, and risk perception.
Pediatr. Diabetes 16, 287-298 (2014)
Roßbauer, M.
Postpartale Entwicklung von Diabetes bei Müttern mit Gestationsdiabetes sowie Übergewicht bei deren Kindern und die Rolle des Darm-Mikrobioms.
München, Technische Universität, Fakultät Wissenschaftszentrum Weihenstephan, Diss., 2014, 177 S.
Schlosser, M.* ; Lampasona, V.* ; Williams, A.J.K.* ; Mueller, P.W.* ; Pittman, D.L.* ; Winter, W.E.* ; Akolkar, B.* ; Achenbach, P.
Combined appearance of autoantibodies against GAD, IA-2, insulin and ZnT8 in the islet autoantibody standardisation program 2013 proficiency workshop.
Diabetologia 57, S145 (2014)
Serr, I. ; Weigmann, B.* ; Franke, R.K. ; Daniel, C.
Treg vaccination in autoimmune type 1 diabetes.
Biodrugs 28, 7-16 (2014)
Smith, L.B.* ; Lynch, K.F.* ; Baxter, J.* ; Lernmark, B.* ; Roth, R.* ; Simell, T.* ; Johnson, S.B.* ; TEDDY Study Group (Ziegler, A.-G. ; Beyerlein, A. ; Henneberger, L. ; Hummel, M. ; Hummel, S. ; Knopff, A. ; Krause, S. ; Peplow, C. ; Pflüger, M. ; Roth, R. ; Schenkel, J. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Winkler, C.)
Factors associated with maternal-reported actions to prevent type 1 diabetes in the first year of the TEDDY study.
Diabetes Care 37, 325-331 (2014)
Stand, E.
Saxagliptin, alogliptin, and cardiovascular outcomes.
N. Engl. J. Med. 370, 483-484 (2014)
Standl, E.* ; Erbach, M.* ; Schnell, O.*
Dipeptidyl-peptidase-4 inhibitors and heart failure: Class effect, substance-specific effect, or chance effect?
Curr. Treat. Options Oncol. 16:353 (2014)
Stumpp, C.* ; Beyerlein, A. ; Ziegler, A.-G. ; Bonifacio, E.*
Neonatal and infant beta cell hormone concentrations in relation to type 1 diabetes risk.
Pediatr. Diabetes 15, 528-533 (2014)
Warncke, K.* ; Dressel, P.* ; Ziegler, A.-G. ; Steinborn, M.* ; Bonfig, W.* ; Burdach, S.* ; Engelsberger, I.*
Severe pretreatment cerebral edema in newly diagnosed type 1 diabetes.
Horm. Res. Paediatr. 81, 285-288 (2014)
Warncke, K. ; Engelsberger, I.*
Erschwerte Differenzialdiagnose bei einem 17-jährigen Patienten : Typ-1-Diabetes? Typ-2-Diabetes? Oder „Doppel-Diabetes“?
Dtsch. Med. Wochenschr. 139, 1097-1099 (2014)
Winkler, C. ; Krumsiek, J. ; Buettner, F. ; Angermüller, C. ; Giannopoulou, E.Z. ; Theis, F.J. ; Ziegler, A.-G. ; Bonifacio, E.
Feature ranking of type 1 diabetes susceptibility genes improves prediction of type 1 diabetes.
Diabetologia 57, 2521-2529 (2014)
Winkler, C. ; Krumsiek, J. ; Buettner, F. ; Angermüller, C. ; Giannopoulou, E.Z. ; Theis, F.J. ; Ziegler, A.-G. ; Bonifacio, E.
Erratum to: Feature ranking of type 1 diabetes susceptibility genes improves prediction of type 1 diabetes.
Diabetologia 58, 206 (2014)
Yang, J.* ; Lernmark, A.* ; Uusitalo, U.M.* ; Lynch, K.F.* ; Veijola, R.* ; Winkler, C. ; Larsson, H.E.* ; Rewers, M.* ; She, J.X.* ; Ziegler, A.-G. ; Simell, O.G.* ; Hagopian, W.A.* ; Akolkar, B.* ; Krischer, J.P.* ; Vehik, K.* ; TEDDY Study Group (Beyerlein, A. ; Bonifacio, E. ; Hummel, M. ; Hummel, S. ; Foterek, K. ; Kersting, M. ; Knopff, A. ; Koletzko, S. ; Peplow, C. ; Roth, R. ; Stock, J. ; Strauss, E. ; Warncke, K.)
Prevalence of obesity was related to HLA-DQ in 2-4 year old children at genetic risk for type 1 diabetes.
Int. J. Obes. 38, 1491-1496 (2014)
Achenbach, P. ; Hummel, M.* ; Thümer, L.* ; Boerschmann, H.* ; Höfelmann, D. ; Ziegler, A.-G.
Characteristics of rapid vs slow progression to type 1 diabetes in multiple islet autoantibody-positive children.
Diabetologia 56, 1615-1622 (2013)
Aronsson, C.A.* ; Vehik, K.* ; Yang, J.* ; Uusitalo, U.* ; Hay, K.* ; Joslowski, G.* ; Riikonen, A.* ; Ballard, L.* ; Virtanen, S.M.* ; Norris, J.M.* ; TEDDY Study Group
Use of dietary supplements in pregnant women in relation to sociodemographic factors - a report from The Environmental Determinants of Diabetes in the Young (TEDDY) study.
Public Health Nutr. 16, 1390-1402 (2013)
Awa, W.L.* ; Boehm, B.O.* ; Rosinger, S.* ; Achenbach, P. ; Ziegler, A.-G. ; Krause, S. ; Meissner, T.* ; Wiegand, S.* ; Reinehr, T.* ; Kapellen, T.* ; Karges, B.* ; Eiermann, T.* ; Schober, E.* ; Holl, R.W.*
HLA-typing, clinical, and immunological characterization of youth with type 2 diabetes mellitus phenotype from the German/Austrian DPV database.
Pediatr. Diabetes 14, 562-574 (2013)
Beyerlein, A. ; Wehweck, F. ; Ziegler, A.-G. ; Pflüger, M.
Respiratory infections in early life and the development of islet autoimmunity in children at increased type 1 diabetes risk: Evidence from the BABYDIET study.
JAMA Pediatr. 167, 800-807 (2013)
Bund, D. ; Buhmann, R. ; Gökmen, F. ; Zorn, J. ; Kolb, H.-J. ; Schmetzer, H.M.*
Minor histocompatibility antigen UTY as target for graft-versus-leukemia and graft-versus-haematopoiesis in the canine model.
Scand. J. Immunol. 77, 39-53 (2013)
D'Orlando, O.* ; Zhao, F.* ; Kasper, B.* ; Orinska, Z.* ; Müller, J.* ; Hermans-Borgmeyer, I.* ; Griffiths, G.M.* ; Zur Stadt, U.* ; Bulfone-Paus, S.*
Syntaxin 11 is required for NK and CD8⁺ T-cell cytotoxicity and neutrophil degranulation.
Eur. J. Immunol. 43, 194-208 (2013)
Eugster, A.* ; Lindner, A.* ; Heninger, A.K.* ; Wilhelm, C.* ; Dietz, S.* ; Ziegler, A.-G. ; Bonifacio, E.*
Measuring T cell receptor and T cell gene expression diversity in antigen-responsive human CD4+ T cells.
J. Immunol. Methods 400-401, 13-22 (2013)
Gimm, T. ; Hoeland, A.* ; Schwarz, M.* ; Hossain, H.* ; Ehrhardt, H.* ; Gortner, L.* ; Scholz, M.* ; Reicherzer, T.* ; Hauck, S.M. ; Hilgendorff, A.
Identification of biomarkers for early diagnosis in BPD.
Eur. Respir. J. 42 (2013)
Gobel, U.* ; von Kries, R.* ; Teske, C.* ; Schneider, D.T.* ; Beyerlein, A.* ; Bernbeck, B.* ; Calaminus, G.*
Brain metastases during follow-up of children and adolescents with extracranial malignant germ cell tumors: risk adapted management decision tree analysis based on data of the MAHO/MAKEI-registry.
Pediatr. Blood Cancer 60, 217-223 (2013)
Harsunen, M.H. ; Puff, R. ; D'Orlando, O. ; Giannopoulou, E.Z. ; Lachmann, L. ; Beyerlein, A. ; von Meyer, A.* ; Ziegler, A.-G.
Reduced blood leukocyte and neutrophil numbers in the pathogenesis of type 1 diabetes.
Horm. Metab. Res. 46, 467-470 (2013)
Heninger, A.K.* ; Monti, P.* ; Wilhelm, C.* ; Schwaiger, P.* ; Kuehn, D.* ; Ziegler, A.-G. ; Bonifacio, E.*
Activation of islet autoreactive naive T cells in infants is influenced by homeostatic mechanisms and antigen presenting capacity.
Diabetes 62, 2059-2066 (2013)
Hummel, S. ; Much, D. ; Rossbauer, M. ; Ziegler, A.-G. ; Beyerlein, A.
Postpartum outcomes in women with gestational diabetes and their offspring: POGO study design and first-year results.
Rev. Diabet. Stud. 10, 49-57 (2013)
Lee, H.S.* ; Briese, T.* ; Winkler, C. ; Rewers, M.* ; Bonifacio, E.* ; Hyoty, H.* ; Pflueger, M. ; Simell, O.* ; She, J.X.* ; Hagopian, W.* ; Lernmark, A.* ; Akolkar, B.* ; Krischer, J.P.* ; Ziegler, A.-G. ; TEDDY Study Group
Next-generation sequencing for viruses in children with rapid-onset type 1 diabetes.
Diabetologia 56, 1705-1711 (2013)
Monti, P.* ; Brigatti, C.* ; Krasmann, M. ; Ziegler, A.-G. ; Bonifacio, E.*
Concentration and activity of the soluble form of the interleukin-7 receptor α in type I diabetes identifies an interplay between hyperglycemia and immune function.
Diabetes 62, 2500-2508 (2013)
Moran, A.* ; Bundy, B.* ; Becker, D.J.* ; Dimeglio, L.A.* ; Gitelman, S.E.* ; Goland, R.* ; Greenbaum, C.J.* ; Herold, K.C.* ; Marks, J.B.* ; Raskin, P.* ; Sanda, S.* ; Schatz, D.* ; Wherrett, D.K.* ; Wilson, D.M.* ; Krischer, J.P.* ; Skyler, J.S.* ; Pickersgill, L.* ; de Koning, E.* ; Ziegler, A.-G. ; Böehm, B.* ; Badenhoop, K.* ; Schloot, N.* ; Bak, J.F.* ; Pozzilli, P.* ; Mauricio, D.* ; Donath, M.Y.* ; Castaño, L.* ; Wagner, A.* ; Lervang, H.H.* ; Perrild, H.* ; Mandrup-Poulsen, T.*
Interleukin-1 antagonism in type 1 diabetes of recent onset: Two multicentre, randomised, double-blind, placebo-controlled trials.
Lancet 381, 1905-1915 (2013)
Much, D. ; Brunner, S.* ; Vollhardt, C.* ; Schmid, D.* ; Sedlmeier, E.-M. ; Brüderl, M.* ; Heimberg, E.* ; Bartke, N.* ; Boehm, G.* ; Bader, B.L.* ; Amann-Gassner, U. ; Hauner, H.
Breast milk fatty acid profile in relation to infant growth and body composition: results from the INFAT study.
Pediatr. Res. 74, 230-237 (2013)
Raab, J. ; Haupt, F. ; Kordonouri, O.* ; Scholz, M.* ; Wosch, A. ; Ried, C.* ; Aschemeier, B.* ; Danne, T.* ; Ziegler, A.-G. ; Winkler, C.
Continuous rise of insulin resistance before and after the onset of puberty in children at increased risk for type 1 diabetes - a cross-sectional analysis.
Diabetes Metab. Res. Rev. 29, 631-635 (2013)
Riedel, C.* ; von Kries, R.* ; Fenske, N.* ; Strauch, K. ; Ness, A.R.* ; Beyerlein, A.
Interactions of genetic and environmental risk factors with respect to body fat mass in children: Results from the ALSPAC study.
Obesity 21, 1238-1242 (2013)
Vehik, K.* ; Fiske, S.W.* ; Logan, C.A.* ; Agardh, D.* ; Cilio, C.M.* ; Hagopian, W.* ; Simell, O.* ; Roivainen, M.* ; She, J.X.* ; Briese, T.* ; Oikarinen, S.* ; Hyoty, H.* ; Ziegler, A.-G. ; Rewers, M.* ; Lernmark, A.* ; Akolkar, B.* ; Krischer, J.P.* ; Burkhardt, B.R.*
Methods, quality control and specimen management in an international multicentre investigation of type 1 diabetes: TEDDY.
Diabetes Metab. Res. Rev. 29, 557-567 (2013)
von Boehmer, H.* ; Daniel, C.
Therapeutic opportunities for manipulating TReg cells in autoimmunity and cancer.
Nat. Rev. Drug Discov. 12, 51-63 (2013)
Warncke, K. ; Krasmann, M. ; Puff, R. ; Dunstheimer, D.* ; Ziegler, A.-G. ; Beyerlein, A.
Does diabetes appear in distinct phenotypes in young people? Results of the diabetes mellitus Incidence Cohort Registry (DiMelli).
PLoS ONE 8:e74339 (2013)
Williams, A.J.K.* ; Lampasona, V.* ; Schlosser, M.* ; Mueller, P.W.* ; Pittman, D.* ; Winter, W.E.* ; Wyatt, R.* ; Akolkar, B.* ; Bingley, P.J.* ; Achenbach, P.
N-terminally truncated GAD discriminates progression in GAD antibody positive relatives of patients with type 1 diabetes.
Diabetologia 56, S17 (2013)
Ziegler, A.-G. ; Rewers, M.* ; Simell, O.* ; Simell, T.* ; Lempainen, J.* ; Steck, A.* ; Winkler, C. ; Ilonen, J.* ; Veijola, R.* ; Knip, M.* ; Bonifacio, E.* ; Eisenbarth, G.S.*
Seroconversion to multiple islet autoantibodies and risk of progression to diabetes in children.
JAMA 309, 2473-2479 (2013)
Adler, K. ; Krause, S.* ; Fuchs, Y.F.* ; Foertsch, K.* ; Ziegler, A.-G. ; Bonifacio, E.*
The effect of gestation and fetal mismatching on the development of autoimmune diabetes in non-obese diabetic mice.
Clin. Exp. Immunol. 168, 274-278 (2012)
Baxter, J.* ; Vehik, K.* ; Johnson, S.B.* ; Lernmark, B.* ; Roth, R.* ; Simell, T.*
Differences in recruitment and early retention among ethnic minority participants in a large pediatric cohort: the TEDDY Study.
Contemp Clin Trials 33, 633-640 (2012)
Baxter, J.E.* ; Vehik, K.S.* ; Johnson, S.B.* ; Lernmark, B.* ; Roth, R.M.* ; Simell, T.T.* ; Rewers, M.J.* ; Barriga, K.J.* ; Bautista, K.* ; Baxter, J.M.* ; Eisenbarth, G.S.* ; Frank, N.* ; Gesualdo, P.* ; Hoffman, M.R.* ; Ide, L.* ; Karban, R.* ; Liu, E.* ; Norris, J.M.* ; Waugh, K.C.* ; Samper-Imaz, A.* ; Steck, A.K.* ; She, J.* ; Schatz, D.A.* ; Hopkins, D.I.* ; Steed, L.* ; Thomas, J.L.* ; Silvis, K.* ; Haller, M.J.* ; Shankar, M.N.* ; English, K.* ; McIndoe, R.A.* ; Liu, H.* ; Nechtman, J.F.* ; Williams, J.G.* ; Foghis, G.* ; Stephen, W.* ; Anderson, M.D.* ; Ziegler, A.-G.* ; Achenbach, A.* ; Boerschmann, H.* ; Bonifacio, E.* ; Bunk, M.* ; Försch, J.* ; Henneberger, L.* ; Hummel, M.* ; Hummel, S.* ; Joslowski, G.* ; Kersting, M.* ; Knopff, A.* ; Kocher, N.* ; Koletzko, S.* ; Krause, S.* ; Mann, A.* ; Matzke, C.* ; Mittermeier, A.* ; Peplow, C.* ; Pflüger, M.* ; Ramminger, C.* ; Strauss, E.* ; Rash-Sur, S.* ; Roth, R.* ; Schenkel, J.* ; Stock, J.* ; Voit, K.* ; Winkler, C.* ; Wosch, A.* ; Zwilling, M.* ; Simell, O.G.* ; Näntö-Salonen, K.M.* ; Ilonen, J.S.* ; Knip, M.* ; Tuula Simell, V.* ; Hyoty, H.* ; Virtanen, S.M.* ; Kronberg-Kippilä, C.* ; Sjöberg, M.* ; Simell, B.* ; Ruohonen, E.* ; Romo, M.* ; Mantymaki, E.* ; Schroderus, H.* ; Nyblom, M.* ; Stenius, A.* ; Lernmark, A.* ; Agardh, D.J.* ; Almgren, P.* ; Andersson, E.M.* ; Andrén Aronsson, C.* ; Ask, M.* ; Karlsson, U.M.* ; Cilio, C.M.* ; Bremer, J.* ; Ericson-Hallström, E.* ; Gard, T.* ; Gerardsson, J.* ; Hansson, G.L.* ; Hansen, M.V.* ; Hyberg, S.* ; Håkansson, R.* ; Johansen, F.* ; Jonsson, L.* ; Larsson, H.E.* ; Markan, M.* ; Massadakis, T.* ; Melin, J.* ; Månsson-Martinez, M.* ; Nilsson, A.M.* ; Rahmati, K.* ; Järvirova, M.S.* ; Sibthorpe, S.* ; Sjöberg, B.* ; Skogberg, A.* ; Törn, C.* ; Wallin, A.M.M.* ; Wimar, A.* ; Åberg, S.* ; Hagopian, W.A.* ; Yan, X.* ; Killian, M.* ; Cowen Crouch, C.* ; Hay, K.* ; Ayres, S.* ; Adams, C.* ; Bratrude, B.* ; Coughlin, D.* ; Fowler, G.* ; Franco, C.* ; Hammar, C.* ; Heaney, D.* ; Marcus, P.* ; Meyer, A.* ; Mulenga, D.* ; Scott, E.M.* ; Skidmore, J.C.* ; Stabbert, J.* ; Stepitova, V.* ; Williams, N.J.* ; Becker, D.J.* ; Franciscus, M.* ; Dalmagro-Elias, M.E.* ; Daftary, A.R.* ; Krischer, J.P.* ; Abbondondolo, M.* ; Ballard, L.* ; Brown, R.L.* ; Burkhardt, B.R.* ; Cuthbertson, D.D.* ; Eberhard, C.* ; Fiske, S.W.* ; Gowda, V.* ; Hadley, D.J.* ; Lee, H.* ; Liu, S.* ; Lynch, K.F.* ; Malloy, J.F.* ; McCarthy, C.* ; McLeod, W.D.* ; Smith, L.B.* ; Smith, S.B.* ; Uusitalo, U.M.* ; Vehik, K.* ; Washington, E.* ; Yang, J.* ; Akolkar, B.* ; Briese, T.C.* ; Erlich, H.A.* ; Oberste, S.M.*
Differences in recruitment and early retention among ethnic minority participants in a large pediatric cohort: The TEDDY Study.
Contemp Clin Trials 33, 633-640 (2012)
Bechtold, S.* ; Beyerlein, A.* ; Ripperger, P.* ; Roeb, J.* ; Dalla Pozza, R.* ; Häfner, R.* ; Haas, J.P.* ; Schmidt, H.*
Total pubertal growth in patients with juvenile idiopathic arthritis treated with growth hormone: analysis of a single center.
Growth Horm. IGF Res. 22, 180-185 (2012)
Beyerlein, A.* ; Nehring, I.* ; Rosario, A.S.* ; von Kries, R.*
Gestational diabetes and cardiovascular risk factors in the offspring: results from a cross-sectional study.
Diabetic Med. 29, 378-384 (2012)
Chatenoud, L.* ; Warncke, K. ; Ziegler, A.-G.
Clinical immunologic interventions for the treatment of type 1 diabetes.
Cold Spring Harbor Perspect. Med. 2:a007716 (2012)
Dames, P.* ; Weise, M.* ; Puff, R.* ; Göke, B.* ; Parhofer, K.G.* ; Seissler, J.* ; Lechner, A.*
Suppression of the nuclear factor Eny2 increases insulin secretion in poorly functioning INS-1E insulinoma cells.
J. Diabetes Res. 2012:460869 (2012)
Gerlach, K.* ; Daniel, C. ; Lehr, H.A.* ; Nikolaev, A.* ; Gerlach, T.* ; Atreya, R.* ; Rose-John, S.* ; Neurath, M.F.* ; Weigmann, B.*
Transcription factor NFATc2 controls the emergence of colon cancer associated with IL-6-dependent colitis.
Cancer Res. 72, 4340-4350 (2012)
Halbritter, S. ; Fedrigo, M. ; Höllriegl, V. ; Szymczak, W. ; Maier, J.M. ; Ziegler, A.-G. ; Hummel, M.*
Human breath gas analysis in the screening of gestational diabetes mellitus.
Diabetes Technol. Ther. 14, 917-925 (2012)
Hauner, H.* ; Much, D.* ; Vollhardt, C.* ; Brunner, S.* ; Schmid, D.* ; Sedlmeier, E.-M.* ; Heimberg, E.* ; Schuster, T.* ; Zimmermann, A.* ; Schneider, K.T.* ; Bader, B.L.* ; Amann-Gassner, U.*
Effect of reducing the n-6:n-3 long-chain PUFA ratio during pregnancy and lactation on infant adipose tissue growth within the first year of life: an open-label randomized controlled trial.
Am. J. Clin. Nutr. 95, 383-394 (2012)
Howson, J.M.M.* ; Krause, S.* ; Stevens, H.* ; Smyth, D.J.* ; Wenzlau, J.M.* ; Bonifacio, E.* ; Hutton, J.* ; Ziegler, A.-G. ; Todd, J.A.* ; Achenbach, P.
Genetic association of zinc transporter 8 (ZnT8) autoantibodies in type 1 diabetes cases.
Diabetologia 55, 1978-1984 (2012)
Johnson, K.* ; Wong, R.* ; Barriga, K.J.* ; Klingensmith, G.* ; Ziegler, A.-G.* ; Rewers, M.J.* ; Steck, A.K.*
rs11203203 is associated with type 1 diabetes risk in population pre-screened for high-risk HLA-DR,DQ genotypes.
Pediatr. Diabetes 13, 611-615 (2012)
Krause, S. ; Achenbach, P.
Neue Immunplattform zur Messung von Autoantikörpern bei Diabetes mellitus.
Diabetes Stoffwechs. Herz 21, 171-173 (2012)
Krause, S. ; Chmiel, R.* ; Bonifacio, E.* ; Scholz, M. ; Powell, M.* ; Furmaniak, J.* ; Smith, B.R.* ; Ziegler, A.-G. ; Achenbach, P.
IA-2 autoantibody affinity in children at risk for type 1 diabetes.
Clin. Immunol. 145, 224-229 (2012)
Maier, J.M.* ; Hummel, M.* ; Halbritter, S. ; Fedrigo, M. ; Höllriegl, V. ; Ziegler, A.-G. ; Szymczak, W.
Piloststudie zu Gestationsdiabetes.
DDG Informationen 6, 170-171 (2012)
Salamini, F.* ; Abels, M.* ; Hyoty, H.* ; Vaziri-Sani, F.* ; Aronsson, C.A.* ; Vehik, K.* ; Delli, A.* ; Hagopian, W.* ; Rewers, M.* ; Ziegler, A.-G.* ; Simell, O.* ; Akolkar, B.* ; Krischer, J.* ; She, J.* ; Lernmark, A.*
Detection of lactobacilli in monthly mail-in stool samples from 3-18 months old infants at genetic risk for type 1 diabetes.
Int. J. Probiotics Prebiotics 7, 135-144 (2012)
Thummerer, Y.* ; von Kries, R.* ; Marton, M.A.* ; Beyerlein, A.*
Is age or speed the predominant factor in the development of trunk movement in normally developing children?
Gait Posture 35, 23-28 (2012)
Weigmann, B.* ; Daniel, C.
Treg vaccination with a strong-agonistic insulin mimetope.
Curr. Diab. Rep. 12, 463-470 (2012)
Weigmann, B.* ; Franke, R.K. ; Daniel, C.
Immunotherapy in autoimmune type 1 diabetes.
Rev. Diabet. Stud. 9, 68-81 (2012)
Winkler, C. ; Raab, J.* ; Grallert, H. ; Ziegler, A.-G.
Lack of association of type 2 diabetes susceptibility genotypes and body weight on the development of islet autoimmunity and type 1 diabetes.
PLoS ONE 7:e35410 (2012)
Winkler, C. ; Krumsiek, J. ; Lempainen, J. ; Achenbach, P. ; Grallert, H. ; Giannopoulou, E.Z. ; Bunk, M. ; Theis, F.J. ; Bonifacio, E.* ; Ziegler, A.-G.
A strategy for combining minor genetic susceptibility genes to improve prediction of disease in type 1 diabetes.
Genes Immun. 13, 549-555 (2012)
Winkler, C. ; Schober, E.* ; Ziegler, A.-G. ; Holl, R.W.*
Markedly reduced rate of diabetic ketoacidosis at onset of type 1 diabetes in relatives screened for islet autoantibodies.
Pediatr. Diabetes 13, 308-313 (2012)
TEENDIAB Study Group (Ziegler, A.-G. ; Meier-Stiegen, F.* ; Winkler, C. ; Bonifacio, E.*)
Prospective evaluation of risk factors for the development of islet autoimmunity and type 1 diabetes during puberty - TEENDIAB: Study design.
Pediatr. Diabetes 13, 438-443 (2012)
Ziegler, A.-G. ; Bonifacio, E.* ; BABYDIAB-BABYDIET Study Group
Age-related islet autoantibody incidence in offspring of patients with type 1 diabetes.
Diabetologia 55, 1937-1943 (2012)
Ziegler, A.-G. ; Wallner, M. ; Kaiser, I.* ; Rossbauer, M. ; Harsunen, M.H. ; Lachmann, L.* ; Maier, J.M.* ; Winkler, C. ; Hummel, S.
Long-term protective effect of lactation on the development of type 2 diabetes in women with recent gestational diabetes mellitus.
Diabetes 61, 3167-3171 (2012)
Achenbach, P. ; Hummel, M.*
Verdacht auf Typ-1-Diabetes. So sichern Sie die Diagnose.
MMW-Fortschr. Med. 153, 45-47 (2011)
Adler, K.* ; Mueller, D.B.* ; Achenbach, P.* ; Krause, S.* ; Heninger, A.K.* ; Ziegler, A.-G.* ; Bonifacio, E.*
Insulin autoantibodies with high affinity to the bovine milk protein alpha casein.
Clin. Exp. Immunol. 164, 42-49 (2011)
Benhalima, K.* ; Standl, E. ; Mathieu, C.*
The importance of glycemic control: How low should we go with HbA1c? Start early, go safe, go low.
25, 202-207 (2011)
Beyerlein, A.* ; Schiessl, B.* ; Lack, N.* ; von Kries, R.*
Associations of gestational weight loss with birth-related outcome: a retrospective cohort study.
BJOG 118, 55-61 (2011)
Beyerlein, A.* ; Toschke, A.M.* ; Schaffrath Rosario, A.* ; von Kries, R.*
Risk factors for obesity: further evidence for stronger effects on overweight children and adolescents compared to normal-weight subjects.
PLoS ONE 6:e15739 (2011)
Beyerlein, A.* ; Rückinger, S.* ; Toschke, A.M.* ; Schaffrath Rosario, A.* ; von Kries, R.*
Is low birth weight in the causal pathway of the association between maternal smoking in pregnancy and higher BMI in the offspring?
Eur. J. Epidemiol. 26, 413-420 (2011)
Beyerlein, A.* ; von Kries, R.*
Breastfeeding and body composition in children: will there ever be conclusive empirical evidence for a protective effect against overweight?
Am. J. Clin. Nutr. 94, 1772S-1775S (2011)
Beyerlein, A.* ; von Kries, R.* ; Ness, A.R.* ; Ong, K.K.*
Genetic markers of obesity risk: stronger associations with body composition in overweight compared to normal-weight children.
PLoS ONE 6:e19057 (2011)
Bonifacio, E. ; Warncke, K. ; Winkler, C. ; Wallner, M.* ; Ziegler, A.-G.
Cesarean section and interferon-induced helicase gene polymorphisms combine to increase childhood type 1 diabetes risk.
Diabetes 60, 3300-3306 (2011)
Dalla Pozza, R.* ; Beyerlein, A.* ; Thilmany, C.* ; Weissenbacher, C.* ; Netz, H.* ; Schmidt, H.* ; Bechtold, S.*
The effect of cardiovascular risk factors on the longitudinal evolution of the carotid intima medial thickness in children with type 1 diabetes mellitus.
Cardiovasc. Diabetol. 10:53 (2011)
Daniel, C.* ; von Boehmer, H.*
Extrathymic generation of regulatory T cells--chances and challenges for prevention of autoimmune disease.
Adv. Immunol. 112, 177-213 (2011)
Daniel, C.* ; von Boehmer, H.*
Extra-thymically induced regulatory T cells: do they have potential in disease prevention?
Semin. Immunol. 23, 410-417 (2011)
Daniel, C.* ; Weigmann, B.* ; Bronson, R.* ; von Boehmer, H.*
Prevention of type 1 diabetes in mice by tolerogenic vaccination with a strong agonist insulin mimetope.
J. Exp. Med. 208, 1501-1510 (2011)
Daniel, C.* ; Ploegh, H.* ; von Boehmer, H.*
Antigen-specific induction of regulatory T cells in vivo and in vitro.
Methods Mol. Biol. 707, 173-185 (2011)
Elding Larsson, H.* ; Vehik, K.* ; Bell, R.* ; Dabelea, D.* ; Dolan, L.* ; Pihoker, C.* ; Knip, M.* ; Veijola, R.* ; Lindblad, B.* ; Samuelsson, U.* ; Höll, R.* ; Haller, M.J.*
Reduced prevalence of diabetic ketoacidosis at diagnosis of type 1 diabetes in young children participating in longitudinal follow-up.
Diabetes Care 34, 2347-2352 (2011)
Hagopian, W.A.* ; Erlich, H.* ; Erlich, H.* ; Lernmark, A.* ; Rewers, M.* ; Ziegler, A.-G.* ; Simell, O.* ; Akolkar, B.* ; Vogt, R.* ; Vogt, R.* ; Blair, A.* ; Ilonen, J.* ; Krischer, J.* ; She, J.*
The Environmental Determinants of Diabetes in the Young (TEDDY): Genetic criteria and international diabetes risk screening of 421 000 infants.
Pediatr. Diabetes 12, 733-743 (2011)
Hagopian, WA* ; Erlich, H* ; Lernmark, A.* ; Rewers, M* ; Ziegler, A.-G.* ; Simell, O* ; Akolkar, B* ; Vogt, R* ; Blair, A.* ; Ilonen, J* ; Krischer, J* ; She, J*
The Environmental Determinants of Diabetes in the Young (TEDDY): genetic criteria and international diabetes risk screening of 421 000 infants.
Pediatr. Diabetes 12, 733-743 (2011)
Harsunen, M.H.* ; Warncke, K.
Primär- und Sekundärprävention des Typ-1-Diabetes.
Diabetologe 7, 561-567 (2011)
Hart, P.* ; Hammer, H.* ; Abrahamian, H.* ; Ebenbichler, C.* ; Hummel, M.* ; Matthaei, S.* ; Schnell, O.* ; Spinas, G.* ; Weitgasser, R.* ; Wiesli, P.* ; Philippe, J.*
Diagnostik und Therapie der exokrinen Pankreasinsuffizienz bei Diabetes Mellitus
Diabetes Stoffwechs. Herz 20, 185-190 (2011)
Hummel, M.* ; Achenbach, P.
MMW-Notfallcheckliste. Ketoazidotisches Koma.
MMW-Fortschr. Med. 153, 48-49 (2011)
Hummel, M.* ; Ziegler, A.-G.*
Epidemiologie, Ätiologie und Pathogenese des Typ 1 Diabetes.
Diabetes Res. Clin. Pract. (2011)
Hummel, M.*
Insulin therapy in type 2 diabetes.
MMW-Fortschr. Med. 153, 56-59 (2011)
Hummel, M.*
Diabetes assoziierte gastrointestinale Komplikationen
Der Hausarzt 10, 32-36 (2011)
Hummel, M.*
Umgang mit Diabetes im Lebensalltag.
Der Hausarzt (2011)
Hummel, S. ; Pflüger, M. ; Hummel, M. ; Bonifacio, E.* ; Ziegler, A.-G.
Primary dietary intervention study to reduce the risk of islet autoimmunity in children at increased risk for type 1 diabetes: The BABYDIET study.
Diabetes Care 34, 1301-1305 (2011)
Hummel, S. ; Ziegler, A.-G.
Early determinants of type 1 diabetes: Experience from the BABYDIAB and BABYDIET studies.
Am. J. Clin. Nutr. 94, 1821-1823 (2011)
Kempf, K.* ; Füth, R.* ; Dinh, W.* ; Bansemir, L.* ; Köhler, T.* ; Bufe, A.* ; Scheffold, T.H.* ; Standl, E. ; Martin, S.D.* ; Lankisch, M.R.*
Screening for overt diabetes by oral glucose tolerance test: Stratification by fasting blood glucose and patients' age improve practicability of guidelines in cardiological routine.
150, 201-205 (2011)
Lampasona, V.* ; Schlosser, M.* ; Mueller, P.W.* ; Williams, A.J.* ; Wenzlau, J.M.* ; Hutton, J.C.* ; Achenbach, P.
Diabetes antibody standardization program: First proficiency evaluation of assays for autoantibodies to zinc transporter 8.
Clin. Chem. 57, 1693-1702 (2011)
Meier-Stiegen, F.* ; Ziegler, A.-G.
Prospective observational studies of the development of type 1 diabetes during childhood and puberty.
Dtsch. Med. Wochenschr. 136, 271-275 (2011)
Nehring, I.* ; Schmoll, S.* ; Beyerlein, A.* ; Hauner, H.* ; von Kries, R.*
Gestational weight gain and long-term postpartum weight retention: a meta-analysis.
Am. J. Clin. Nutr. 94, 1225-1231 (2011)
Pflueger, M. ; Seppänen-Laakso, T.* ; Suortti, T.* ; Hyötyläinen, T.* ; Achenbach, P. ; Bonifacio, E.* ; Oresič, M.* ; Ziegler, A.-G.
Age- and islet autoimmunity-associated differences in amino acid and lipid metabolites in children at risk for type 1 diabetes.
Diabetes 60, 2740-2747 (2011)
Puff, R.* ; Dames, P.* ; Weise, M.* ; Göke, B.* ; Seissler, J.* ; Parhofer, K.G.* ; Lechner, A.*
Reduced proliferation and a high apoptotic frequency of pancreatic beta cells contribute to genetically-determined diabetes susceptibility of db/db BKS mice.
Horm. Metab. Res. 43, 306-311 (2011)
Schlosser, M.* ; Mueller, P.W.* ; Achenbach, P. ; Lampasona, V.* ; Bingley, P.J* ; Participating Laboratories*
Diabetes antibody standardization program: First evaluation of assays for autoantibodies to IA-2β.
Diabetes Care 34, 2410-2412 (2011)
Simonen-Tikka, M.-L.* ; Pflueger, M. ; Klemola, P.* ; Savolainen-Kopra, C.* ; Smura, T.* ; Hummel, S. ; Kaijalainen, S.* ; Nuutila, K.* ; Natri, O.* ; Roivainen, M.* ; Ziegler, A.-G.
Human enterovirus infections in children at increased risk for type 1 diabetes: The Babydiet study.
Diabetologia 54, 2995-3002 (2011)
Sterner, Y.* ; Törn, C.* ; Lee, H.S.* ; Larsson, H.* ; Winkler, C. ; McLeod, W.* ; Lynch, K.* ; Simell, O.* ; Ziegler, A.-G. ; Schatz, D.* ; Hagopian, W.* ; Rewers, M.* ; She, J.X.* ; Krischer, J.P.* ; Akolkar, B.* ; Lernmark, A.* ; TEDDY Study Group
Country-specific birth weight and length in type 1 diabetes high-risk HLA genotypes in combination with prenatal characteristics.
J. Perinatol. 31, 764-769 (2011)
Streuling, I.* ; Beyerlein, A.* ; Rosenfeld, E.* ; Hofmann, H.* ; Schulz, T.* ; von Kries, R.*
Physical activity and gestational weight gain: a meta-analysis of intervention trials.
BJOG 118, 278-284 (2011)
Streuling, I.* ; Beyerlein, A.* ; Rosenfeld, E.* ; Schukat, B.* ; von Kries, R.*
Weight gain and dietary intake during pregnancy in industrialized countries--a systematic review of observational studies.
J. Perinat. Med. 39, 123-129 (2011)
Wallner, M.* ; Thuemer, L.* ; Hummel, M.* ; Ziegler, A.-G.*
Treatment of type 1 diabetes is changing - breakthrough in immune intervention?
Diabetol. Stoffwechs. 6, 98-103 (2011)
Winkler, C. ; Lauber, C. ; Adler, K.* ; Grallert, H. ; Illig, T. ; Ziegler, A.-G. ; Bonifacio, E.*
An interferon-induced helicase (IFIH1) gene polymorphism associates with different rates of progression from autoimmunity to type 1 diabetes.
Diabetes 60, 685-690 (2011)
Ziegler, A.-G.* ; Mollenhauer, U. ; Achenbach, P. ; Bonifacio, E.*
Anti-CCL3 autoantibodies are not markers of type 1 diabetes when measured by a commercial ELISA method.
Diabetologia 54, 699-700 (2011)
Ziegler, A.-G. ; Pflueger, M.* ; Winkler, C.* ; Achenbach, P. ; Akolkar, B.* ; Krischer, J.P.* ; Bonifacio, E.*
Accelerated progression from islet autoimmunity to diabetes is causing the escalating incidence of type 1 diabetes in young children.
J. Autoimmun. 37, 3-7 (2011)
Achenbach, P. ; Guo, L.H. ; Gick, C.* ; Adler, K. ; Krause, S.* ; Bonifacio, E.* ; Colman, P.G.* ; Ziegler, A.-G.
A simplified method to assess affinity of insulin autoantibodies.
Clin. Immunol. 137, 415-421 (2010)
Achenbach, P. ; Krause, S. ; Ziegler, A.-G.
Pathogenesis of type 1 diabetes mellitus - Update 2010.
Diabetol. Stoffwechs. 5, R29-R46 (2010)
Adler, K. ; Henneberger, L. ; Huber, C. ; Falk, C. ; Ziegler, A.-G.
Kompetenznetz Diabetes mellitus bündelt deutschlandweite Diabetesexpertise.
Diabetes Stoffwechs. Herz 19, 360-366 (2010)
Beyerlein, A.* ; Hadders-Algra, M.* ; Kennedy, K.* ; Fewtrell, M.* ; Singhal, A.* ; Rosenfeld, E.* ; Lucas, A.* ; Bouwstra, H.* ; Koletzko, B.* ; von Kries, R.*
Infant formula supplementation with long-chain polyunsaturated fatty acids has no effect on Bayley developmental scores at 18 months of age - IPD meta-analysis of 4 large clinical trials.
J. Pediatr. Gastroenterol. Nutr. 50, 79-84 (2010)
Beyerlein, A.* ; Toschke, A.M.* ; von Kries, R.*
Risk factors for childhood overweight: shift of the mean body mass index and shift of the upper percentiles: Results from a cross-sectional study.
Int. J. Obes. 34, 642-648 (2010)
Beyerlein, A.* ; Ness, A.R.* ; Streuling, I.* ; Hadders-Algra, M.* ; von Kries, R.*
Early rapid growth: no association with later cognitive functions in children born not small for gestational age.
Am. J. Clin. Nutr. 92, 585-593 (2010)
Beyerlein, A.* ; Lack, N.* ; von Kries, R.*
Within-population average ranges compared with Institute of Medicine recommendations for gestational weight gain.
Obstet. Gynecol. 116, 1111-1118 (2010)
Beyerlein, A.* ; von Kries, R.* ; Hummel, M.* ; Lack, N.* ; Schiessl, B.* ; Giani, G.* ; Icks, A.*
Improvement in pregnancy-related outcomes in the offspring of diabetic mothers in Bavaria, Germany, during 1987-2007.
Diabetic Med. 27, 1379-1384 (2010)
Boerschmann, H.* ; Pflüger, M. ; Henneberger, L. ; Ziegler, A.-G. ; Hummel, S.
Prevalence and predictors of overweight and insulin resistance in offspring of mothers with gestational diabetes mellitus.
Diabetes Care 33, 1845-1849 (2010)
Boerschmann, H.* ; Walter, M.C.* ; Achenbach, P.* ; Ziegler, A.-G.*
Survey of recent clinical trials of the prevention and immunointervention of type 1 diabetes mellitus.
Dtsch. Med. Wochenschr. 135, 350-354 (2010)
Bonifacio, E.* ; Yu, L.* ; Williams, A.K.* ; Eisenbarth, G.S.* ; Bingley, P.J.* ; Marcovina, S.M.* ; Adler, K.* ; Ziegler, A.-G.* ; Mueller, P.W.* ; Schatz, D.A.* ; Krischer, J.P.* ; Steffes, M.W.* ; Akolkar, B.*
Harmonization of glutamic acid decarboxylase and islet antigen-2 autoantibody assays for national institute of diabetes and digestive and kidney diseases consortia.
J. Clin. Endocrinol. Metab. 95, 3360-7 (2010)
Bonifacio, E.* ; Ziegler, A.-G.*
Advances in the prediction and natural history of type 1 diabetes.
Endocrinol. Metab. Clin. North Am. 39, 513-25 (2010)
Daniel, C.* ; Wennhold, K.* ; Kim, H.J.* ; von Boehmer, H.*
Enhancement of antigen-specific Treg vaccination in vivo.
Proc. Natl. Acad. Sci. U.S.A. 107, 16246-16251 (2010)
Halbritter, S.* ; Szymczak, W. ; Fedrigo, M.* ; Höllriegl, V. ; Meier, J.* ; Ziegler, A.-G.
PTR-MS breath gas analysis during oral glucose tolerance test in gestational diabetes screening .
Vortrag: 5.International PTR-MS Conference, 26-31 January 2011, Obergurgl, A. (2010)
Hale, G.* ; Rebello, P.* ; Al Bakir, I.* ; Bolam, E.* ; Wiczling, P.* ; Jusko, W.J.* ; Vandemeulebroucke, E.* ; Keymeulen, B.* ; Mathieu, C.* ; Ziegler, A.-G.* ; Chatenoud, L.* ; Waldmann, H.*
Pharmacokinetics and antibody responses to the CD3 antibody otelixizumab used in the treatment of type 1 diabetes.
J Clin Pharmacol 50, 1238-48 (2010)
Keymeulen, B.* ; Walter, M.* ; Mathieu, C.* ; Kaufman, L.* ; Gorus, F.* ; Hilbrands, R.* ; Vandemeulebroucke, E.* ; van de Velde, U.* ; Crenier, L.* ; de Block, C.* ; Candon, S.* ; Waldmann, H.* ; Ziegler, A.-G.* ; Chatenoud, L.* ; Pipeleers, D.*
Four-year metabolic outcome of a randomised controlled CD3-antibody trial in recent-onset type 1 diabetic patients depends on their age and baseline residual beta cell mass.
Diabetologia 53, 614-623 (2010)
Keymeulen, B.* ; Candon, S.* ; Fafi-Kremer, S.* ; Ziegler, A.* ; Leruez-Ville, M.* ; Mathieu, C.* ; Vandemeulebroucke, E.* ; Walter, M.* ; Crenier, L.* ; Thervet, E.* ; Legendre, C.* ; Pierard, D.* ; Hale, G.* ; Waldmann, H.* ; Bach, J.F.* ; Seigneurin, J.M.* ; Pipeleers, D.* ; Chatenoud, L.*
Transient Epstein-Barr virus reactivation in CD3 monoclonal antibody-treated patients.
Blood 115, 1145-55 (2010)
Knoop, J.
Chronische Diabeteskomplikationen und kardiovaskuläre Risikofaktoren bei 351 Kindern und Jugendlichen mit Typ-1-Diabetes-mellitus.
Bochum, Ruhr-Universität, Medizinische Fakultät, Diss., 2010, 91 S.
Müller, D.B.
Nahrungsbestandteile und deren Einfluss auf die Pathogenese von Autoimmundiabetes bei Mensch und Maus.
München, Technische Universität, Fakultät Wissenschaftszentrum Weihenstephan, Diss., 2010, 134 S.
Pflüger, M. ; Winkler, C. ; Hummel, S. ; Ziegler, A.-G.
Early infant diet in children at high risk for type 1 diabetes.
Horm. Metab. Res. 42, 143-148 (2010)
Pflüger, M.
Frühkindliche metabolische und immunologische Prägung bei Kindern mit erhöhtem Typ 1 Diabetesrisiko.
München, Technische Universität München, Fakultät Wissenschaftszentrum Weihenstephan für Ernährung, Landnutzung und Umwelt, Diss., 2010, 109 S.
Puff, R.* ; Dames, P.* ; Weise, M.* ; Göke, B.* ; Parhofer, K.G.* ; Lechner, A.*
No non-redundant function of suppressor of cytokine signaling 2 in insulin producing β-cells.
Islets 2, 252-257 (2010)
Rückinger, S.* ; Beyerlein, A.* ; Jacobsen, G.* ; von Kries, R.* ; Vik, T.*
Growth in utero and body mass index at age 5 years in children of smoking and non-smoking mothers.
Early Hum. Dev. 86, 773-777 (2010)
Streuling, I.* ; Beyerlein, A.* ; von Kries, R.*
Can gestational weight gain be modified by increasing physical activity and diet counseling? A meta-analysis of interventional trials.
Am. J. Clin. Nutr. 92, 678-687 (2010)
Thümer, L.* ; Adler, K.* ; Bonifacio, E.* ; Hofmann, F.* ; Keller, M.* ; Milz, C.* ; Munte, A.* ; Ziegler, A.-G.*
German new onset diabetes in the young incident cohort study: DiMelli study design and first-year results.
Rev. Diabet. Stud. 7, 202-8 (2010)
von Kries, R.* ; Ensenauer, R.* ; Beyerlein, A.* ; Amann-Gassner, U.* ; Hauner, H.* ; Rosario, A.S.*
Gestational weight gain and overweight in children: Results from the cross-sectional German KiGGS study.
Int. J. Pediatr. Obes. 6, 45-52 (2010)
Walter, M.* ; Kaupper, T.* ; Adler, K.* ; Foersch, J.* ; Bonifacio, E.* ; Ziegler, A.-G.*
No effect of the 1alpha,25-dihydroxyvitamin D3 on beta-cell residual function and insulin requirement in adults with new-onset type 1 diabetes.
Diabetes Care 33, 1443-1448 (2010)
Warncke, K.* ; Ziegler, A.-G.
Prävention des Typ 1 Diabetes.
Diabetes-Forum, 38-41 (2010)
Wenzlau, J.M.* ; Walter, M.C.* ; Gardner, T.J.* ; Frisch, L.M.* ; Yu, L.* ; Eisenbarth, G.S.* ; Ziegler, A.-G.* ; Davidson, H.W.* ; Hutton, J.C.*
Kinetics of the post-onset decline in zinc transporter 8 autoantibodies in type 1 diabetic human subjects.
J. Clin. Endocrinol. Metab. 95, 4712-9 (2010)
Winkler, C. ; Bonifacio, E.* ; Grallert, H. ; Henneberger, L. ; Illig, T. ; Ziegler, A.-G.
BMI at age 8 years is influenced by the type 2 diabetes susceptibility genes HHEX-IDE and CDKAL1.
Diabetes 59, 2063-2067 (2010)
Ziegler, A.-G. ; Walter, M.*
Loss and preservation of β-cell function: Two treatment regimes targeting T or B lymphocytes.
Curr. Diab. Rep. 10, 323-325 (2010)
Ziegler, A.-G.* ; Nepom, G.T.*
Prediction and pathogenesis in type 1 diabetes.
Immunity 32, 468-78 (2010)
Achenbach, P. ; Lampasona, V.* ; Landherr, U. ; Koczwara, K. ; Krause, S.* ; Grallert, H. ; Winkler, C. ; Pflüger, M. ; Illig, T. ; Bonifacio, E.* ; Ziegler, A.-G.
Autoantibodies to zinc transporter 8 and SLC30A8 genotype stratify type 1 diabetes risk.
Diabetologia 52, 1881-1888 (2009)
Badenhoop, K.* ; Kahles, H.* ; Seidl, C.* ; Kordonouri, O.* ; Lopez, E.R.* ; Walter, M.C.* ; Rosinger, S.* ; Ziegler, A.-G.* ; Böhm, B.O.*
MHC-environment interactions leading to type 1 diabetes: Feasibility of an analysis of HLA DR-DQ alleles in relation to manifestation periods and dates of birth.
Diabetes Obes. Metab. 11, 88-91 (2009)
Beyerlein, A.* ; Schiessl, B.* ; Lack, N.* ; von Kries, R.*
Optimal gestational weight gain ranges for the avoidance of adverse birth weight outcomes: A novel approach.
Am. J. Clin. Nutr. 90, 1552-1558 (2009)
Bonifacio, E.* ; Mayr, A.* ; Knopff, A.* ; Ziegler, A.-G.*
Endocrine autoimmunity in families with type 1 diabetes: Frequent appearance of thyroid autoimmunity during late childhood and adolescence.
Diabetologia 52, 185-192 (2009)
Daniel, C.* ; Nolting, J.* ; von Boehmer, H.*
Mechanisms of self-nonself discrimination and possible clinical relevance.
Immunotherapy 1, 631-644 (2009)
Hummel, S.* ; Pflüger, M.* ; Kreichauf, S.* ; Hummel, M.* ; Ziegler, A.-G.*
Predictors of overweight during childhood in offspring of parents with type 1 diabetes.
Diabetes Care 32, 921-925 (2009)
Müller, D.B.* ; Koczwara, K.* ; Mueller, A.S.* ; Pallauf, J.* ; Ziegler, A.-G.* ; Bonifacio, E.*
Influence of early nutritional components on the development of murine autoimmune diabetes.
Ann. Nutr. Metab. 54, 208-217 (2009)
Nolting, J.* ; Daniel, C.* ; Reuter, S.* ; Stuelten, C.* ; Li, P.* ; Sucov, H.* ; Kim, B.G.* ; Letterio, J.J.* ; Kretschmer, K.* ; Kim, H.J.* ; von Boehmer, H.*
Retinoic acid can enhance conversion of naive into regulatory T cells independently of secreted cytokines.
J. Exp. Med. 206, 2131-2139 (2009)
Rosenfeld, E.* ; Beyerlein, A.* ; Hadders-Algra, M.* ; Kennedy, K.* ; Singhal, A.* ; Fewtrell, M.* ; Lucas, A.* ; Koletzko, B.* ; von Kries, R.*
IPD meta-analysis shows no effect of LC-PUFA supplementation on infant growth at 18 months.
Acta Paediatr. 98, 91-97 (2009)
Schiessl, B.* ; Beyerlein, A.* ; Lack, N.* ; von Kries, R.*
Temporal trends in pregnancy weight gain and birth weight in Bavaria 2000-2007: Slightly decreasing birth weight with increasing weight gain in pregnancy.
J. Perinat. Med. 37, 374-379 (2009)
Stelekati, E.* ; Bahri, R.* ; D'Orlando, O.* ; Orinska, Z.* ; Mittrücker, H.W.* ; Langenhaun, R.* ; Glatzel, M.* ; Bollinger, A.* ; Paus, R.* ; Bulfone-Paus, S.*
Mast cell-mediated antigen presentation regulates CD8+ T cell effector functions.
Immunity 31, 665-676 (2009)
Walter, M.C.* ; Philotheou, A.* ; Bonnici, F.* ; Ziegler, A.-G.* ; Jimenez, R.*
No effect of the altered peptide ligand NBI-6024 on beta-cell residual function and insulin needs in new-onset type 1 diabetes.
Diabetes Care 32, 2036-2040 (2009)
Winkler, C. ; Illig, T. ; Koczwara, K. ; Bonifacio, E.* ; Ziegler, A.-G.
HHEX-IDE polymorphism is associated with low birth weight in offspring with a family history of type 1 diabetes.
J. Clin. Endocrinol. Metab. 94, 4113-4115 (2009)
Winkler, C.* ; Marienfeld, S.* ; Zwilling, M.* ; Bonifacio, E.* ; Ziegler, A.-G.*
Is islet autoimmunity related to insulin sensitivity or body weight in children of parents with type 1 diabetes?
Diabetologia 52, 2072-2078 (2009)
Achenbach, P.* ; Barker, J.* ; Bonifacio, E.*
Modulating the natural history of type 1 diabetes in children at high genetic risk by mucosal insulin immunization.
Curr. Diab. Rep. 8, 87-93 (2008)
Achenbach, P.* ; Bonifacio, E.* ; Williams, A.J.* ; Ziegler, A.-G.* ; Gale, E.A.* ; Bingley, P.J.*
Autoantibodies to IA-2beta improve diabetes risk assessment in high-risk relatives.
Diabetologia 51, 488-492 (2008)
Aoufouchi, S.* ; Faili, A.* ; Zober, C.* ; D'Orlando, O.* ; Weller, S.* ; Weill, J.C.* ; Reynaud, C.A.*
Proteasomal degradation restricts the nuclear lifespan of AID.
J. Exp. Med. 205, 1357-1368 (2008)
Beyerlein, A.* ; Fahrmeir, L.* ; Mansmann, U.* ; Toschke, A.M.*
Alternative regression models to assess increase in childhood BMI.
BMC Med. Res. Methodol. 8:59 (2008)
Beyerlein, A.* ; Toschke, A.M.* ; von Kries, R.*
Breastfeeding and childhood obesity: shift of the entire BMI distribution or only the upper parts?
Obesity 16, 2730-2733 (2008)
Bonifacio, E.* ; Achenbach, P.* ; Pan, L.* ; Ziegler, A.-G.*
Mucosal insulin vaccination for type 1 diabetes prevention.
Exp. Clin. Endocrinol. Diabet. 116, S26-S29 (2008)
Bonifacio, E.* ; Pflüger, M.* ; Marienfeld, S.* ; Winkler, C.* ; Hummel, M.* ; Ziegler, A.-G.*
Maternal type 1 diabetes reduces the risk of islet autoantibodies: Relationships with birthweight and maternal HbA(1c).
Diabetologia 51, 1245-1252 (2008)
Daniel, C.* ; Sartory, N.A.* ; Zahn, N.* ; Radeke, H.H.* ; Stein, J.M.*
Immune modulatory treatment of trinitrobenzene sulfonic acid colitis with calcitriol is associated with a change of a T helper (Th) 1/Th17 to a Th2 and regulatory T cell profile.
J. Pharmacol. Exp. Ther. 324, 23-33 (2008)
Goerlitz, N.* ; Keller, M.* ; Ziegler, A.-G.*
Prävalenzen von Folge- und Begleiterkrankungen des Typ-2-Diabetes. Querschnittuntersuchung an DMP-Teilnehmern in Bayern
Dtsch. Med. Wochenschr. 133, 1667-1672 (2008)
Gohlke, H. ; Ferrari, U.* ; Koczwara, K.* ; Bonifacio, E.* ; Illig, T. ; Ziegler, A.-G.*
SLC30A8 (ZnT8) Polymorphism is Associated with Young Age at Type 1 Diabetes Onset.
Rev. Diabet. Stud. 5, 25-27 (2008)
Görlitz, N.* ; Keller, M.* ; Ziegler, A.-G.*
Prävalenzen von Folge- und Begleiterkrankungen des Typ-2-Diabetes.
Dtsch. Med. Wochenschr. 133, 1667-1672 (2008)
Guo, L.H.* ; Achenbach, P.*
Tracing the pathogenesis of type 1 diabetes: A report on the 44th annual meeting of the European Association for the Study of Diabetes (EASD).
Rev. Diabet. Stud. 5, 171-174 (2008)
Hummel, M.* ; Geigenberger, G.* ; Brand, J.* ; Ziegler, A.-G.* ; Füchtenbusch, M.*
New therapeutic approaches to diabetic gastroparesis.
Med. Klin. 103, 514-518 (2008)
Hummel, S.* ; Hummel, M.* ; Knopff, A.* ; Bonifacio, E.* ; Ziegler, A.-G.*
Stillverhalten bei Frauen mit Gestationsdiabetes
Dtsch. Med. Wochenschr. 133, 180-184 (2008)
Kreichauf, S.* ; Pflüger, M.* ; Hummel, S.* ; Ziegler, A.-G.*
Einfluss des Stillens auf das Risiko für Übergewicht bei Kindern von Müttern mit Typ 1 Diabetes.
Dtsch. Med. Wochenschr. 133, 1173-1177 (2008)
Merluzzi, S.* ; D'Orlando, O.* ; Leonardi, A.* ; Vitale, G.* ; Pucillo, C.*
TRAF2 and p38 are involved in B cells CD40-mediated APE/Ref-1 nuclear translocation: a novel pathway in B cell activation.
Mol. Immunol. 45, 76-86 (2008)
Schoen, S.* ; Sichert-Hellert, W.* ; Hummel, S.* ; Ziegler, A.-G.* ; Kersting, M.*
Breastfeeding duration in families with type 1 diabetes compared to non-affected families: Results from BABYDIAB and DONALD studies in Germany.
Breastfeed. Med. 3, 171-175 (2008)
Toschke, A.M.* ; von Kries, R.* ; Beyerlein, A.* ; Rückinger, S.*
Risk factors for childhood obesity: shift of the entire BMI distribution vs. shift of the upper tail only in a cross sectional study.
BMC Public Health 8:115 (2008)
Winkler, C.* ; Mollenhauer, U.* ; Hummel, S.* ; Bonifacio, E.* ; Ziegler, A.-G.*
Exposure to environmental factors in drinking water: Risk of islet autoimmunity and type 1 diabetes - the BABYDIAB study.
Horm. Metab. Res. 40, 566-571 (2008)
Winkler, C.* ; Hummel, S.* ; Pflüger, M.* ; Ziegler, A.-G.* ; Geppert, J.* ; Demmelmair, H.* ; Koletzko, B.*
The effect of maternal T1DM on the fatty acid composition of erythrocyte phosphatidylcholine and phosphatidylethanolamine in infants during early life.
Eur. J. Nutr. 47, 145-152 (2008)
Winkler, C.* ; Hummel, S.* ; Pflüger, M.* ; Ziegler, A.-G.* ; Geppert, J.* ; Demmelmair, H.* ; Koletzko, B.*
The effect of maternal T1DM on the fatty acid composition of erythrocyte phosphatidylcholine and phosphatidylethanolamine in infants during early life.
Eur. J. Nutr. 47, 145-152 (2008)
Achenbach, P.* ; Schlosser, M.* ; Williams, A.J.* ; Yu, L.* ; Mueller, P.W.* ; Bingley, P.J.* ; Bonifacio, E.*
Combined testing of antibody titer and affinity improves insulin autoantibody measurement: Diabetes Antibody Standardization Program.
Clin. Immunol. 122, 85-90 (2007)
D'Orlando, O.* ; Gri, G.* ; Cattaruzzi, G.* ; Merluzzi, S.* ; Betto, E.* ; Gattei, V.* ; Pucillo, C.*
Outside inside signalling in CD40-mediated B cell activation.
J. Biol. Regul. Homeost. Agents 21, 49-62 (2007)
Daniel, C.* ; Sartory, N.A.* ; Zahn, N.* ; Schmidt, R.* ; Geisslinger, G.* ; Radeke, H.H.* ; Stein, J.M.*
FTY720 ameliorates oxazolone colitis in mice by directly affecting T helper type 2 functions.
Mol. Immunol. 44, 3305-3316 (2007)
Daniel, C.* ; Sartory, N.* ; Zahn, N.* ; Geisslinger, G.* ; Radeke, H.H.* ; Stein, J.M.*
FTY720 ameliorates Th1-mediated colitis in mice by directly affecting the functional activity of CD4+CD25+ regulatory T cells.
J. Immunol. 178, 2458-2468 (2007)
Daniel, C.* ; Schröder, O.* ; Zahn, N.* ; Gaschott, T.* ; Steinhilber, D.* ; Stein, J.M.*
The TGFbeta/Smad 3-signaling pathway is involved in butyrate-mediated vitamin D receptor (VDR)-expression.
J. Cell. Biochem. 102, 1420-1431 (2007)
Hummel, M.* ; Baumgarten, A.* ; Hummel, S.* ; König, S.* ; Ziegler, A.-G.*
Smoking behavior during pregnancy of women with type 1 or gestational diabetes.
Dtsch. Med. Wochenschr. 132, 1153-1158 (2007)
Hummel, M.* ; Schnell, O.*
Insulinpumpentherapie.
Diabetol. Stoffwechs. (2007)
Hummel, S.* ; Hummel, M.* ; Banholzer, J.* ; Hanak, D.* ; Mollenhauer, U.* ; Bonifacio, E.* ; Ziegler, A.-G.*
Development of autoimmunity to transglutaminase C in children of patients with type 1 diabetes: Relationship to islet autoantibodies and infant feeding.
Diabetologia 50, 390-394 (2007)
Hummel, S.* ; Winkler, C.* ; Schoen, S.* ; Knopff, A.* ; Marienfeld, S.* ; Bonifacio, E.* ; Ziegler, A.-G.*
Breastfeeding habits in families with Type 1 diabetes.
Diabetic Med. 24, 671-676 (2007)
Kiviniemi, M.* ; Hermann, R.* ; Nurmi, J.* ; Ziegler, A.-G.* ; Knip, M.* ; Simell, O.* ; Veijola, R.* ; Lövgren, T.* ; Ilonen, J.*
A high-throughput population screening system for the estimation of genetic risk for type 1 diabetes: An application for the TEDDY (the Environmental Determinants of Diabetes in the Young) study.
Diabetes Technol. Ther. 9, 460-472 (2007)
Koczwara, K.* ; Müller, D.* ; Achenbach, P.* ; Ziegler, A.-G.* ; Bonifacio, E.*
Identification of insulin autoantibodies of IgA isotype that preferentially target non-human insulin.
Clin. Immunol. 124, 77-82 (2007)
Marienfeld, S* ; Voigt, M.* ; Bonifacio, E*
Interaction between maternal type 1 diabetes and HLA DR4 increases fetal growth
Diabetologia 49, 68 (2007)
Mayr, A.* ; Schlosser, M.* ; Grober, N.* ; Kenk, H.* ; Ziegler, A.-G.* ; Bonifacio, E.* ; Achenbach, P.*
GAD autoantibody affinity and epitope specificity identify distinct immunization profiles in children at risk for type 1 diabetes.
Diabetes 56, 1527-1533 (2007)
Monti, P.* ; Scirpoli, M.* ; Rigamonti, A.* ; Mayr, A.* ; Jaeger, A.* ; Bonfanti, R.* ; Chiumello, G.* ; Ziegler, A.-G.* ; Bonifacio, E.*
Evidence for in vivo primed and expanded autoreactive T cells as a specific feature of patients with type 1 diabetes.
J. Immunol. 179, 5785-5792 (2007)
Schneider, D.* ; Liaw, L.* ; Daniel, C.* ; Athanasopoulos, A.N.* ; Herrmann, M.* ; Preissner, K.T.* ; Nawroth, P.P.* ; Chavakis, T.*
Inhibition of breast cancer cell adhesion and bone metastasis by the extracellular adherence protein of Staphylococcus aureus.
Biochem. Biophys. Res. Commun. 357, 282-288 (2007)
Achenbach, P.* ; Warncke, K.* ; Reiter, J.* ; Williams, A.J.* ; Ziegler, A.-G.* ; Bingley, P.J.* ; Bonifacio, E.*
Type 1 diabetes risk assessment: improvement by follow-up measurements in young islet autoantibody-positive relatives.
Diabetologia 49, 2969-2976 (2006)
Berriel Diaz, M.* ; Eiden, S.* ; Daniel, C.* ; Steinbrück, A.* ; Schmidt, I.*
Effects of periodic intake of a high-caloric diet on body mass and leptin resistance.
Physiol. Behav. 88, 191-200 (2006)
Daniel, C.* ; Radeke, H.H.* ; Sartory, N.A.* ; Zahn, N.* ; Zuegel, U.* ; Steinmeyer, A.* ; Stein, J.*
The new low calcemic vitamin D analog 22-ene-25-oxa-vitamin D prominently ameliorates T helper cell type 1-mediated colitis in mice.
J. Pharmacol. Exp. Ther. 319, 622-631 (2006)
Hagopian, W.A.* ; Lernmark, A.* ; Rewers, M.J.* ; Simell, O.G.* ; She, J.X.* ; Ziegler, A.-G.* ; Krischer, J.P.* ; Akolkar, B.*
TEDDY--The Environmental Determinants of Diabetes in the Young: An observational clinical trial.
Ann. NY Acad. Sci. 1079, 320-326 (2006)
Hummel, M.* ; Schaaf, L.* ; Füchtenbusch, M.* ; Ziegler, A.-G.*
Hypertonie, Hypokaliämie und rasch progrediente Ödeme bei einem 62-jährigen Diabetiker.
Internist 4, 427-433 (2006)
Hummel, M.* ; Marienfeld, S.* ; Huppmann, M.* ; Knopff, A.* ; Voigt, M.* ; Bonifacio, E.* ; Ziegler, A.-G.*
Interaction between maternal type 1 diabetes and HLA DR4 increases fetal growth.
Diabetologia 49, 68 (2006)
Löbner, K.* ; Knopff, A.* ; Baumgarten, A.* ; Mollenhauer, U.* ; Marienfeld, S.* ; Garrido-Franco, M.* ; Bonifacio, E.* ; Ziegler, A.-G.*
Predictors of postpartum diabetes in women with gestational diabetes mellitus.
Diabetes 55, 792-797 (2006)
Achenbach, P.* ; Bonifacio, E.* ; Ziegler, A.-G.*
Predicting type 1 diabetes.
Curr. Diab. Rep. 5, 98-103 (2005)
Achenbach, P.* ; Ziegler, A.-G.* ; Bonifacio, E.*
Diabetes-related antibodies in euglycemic subjects.
Best Pract. Res. Clin. Endocrinol. Metab. 19, 101-117 (2005)
Achenbach, P.* ; Bonifacio, E.* ; Koczwara, K.* ; Ziegler, A.-G.*
Natural history of type 1 diabetes.
Diabetes 54, S25-S31 (2005)
Bonifacio, E.* ; Mollenhauer, U.* ; Buuck, D.* ; Ziegler, A.-G.*
C-reactive protein concentration is not related to islet autoimmunity status in offspring of parents with type 1 diabetes.
Clin. Immunol. 115, 173-177 (2005)
Daniel, C.* ; Schlauch, T.* ; Zügel, U.* ; Steinmeyer, A.* ; Radeke, H.H.* ; Steinhilber, D.* ; Stein, J.*
22-ene-25-oxa-vitamin D: A new vitamin D analogue with profound immunosuppressive capacities.
Eur. J. Clin. Invest. 35, 343-349 (2005)
Huppmann, M.* ; Baumgarten, A.* ; Ziegler, A.-G.* ; Bonifacio, E.*
Neonatal Bacille Camette-Guerin vaccination and type 1 diabetes.
Diabetes Care 28, 1204-1206 (2005)
Keymeulen, B.* ; Vandemeulebroucke, E.* ; Ziegler, A.-G.* ; Mathieu, C.* ; Kaufman, L.* ; Hale, G.* ; Gorus, F.* ; Goldman, M.* ; Walter, M.C.* ; Candon, S.* ; Schandene, L.* ; Crenier, L.* ; de Block, C.* ; Seigneurin, J.M.* ; De Pauw, P.* ; Pierard, D.* ; Weets, I.* ; Rebello, P.* ; Bird, P.* ; Berrie, E.* ; Frewin, M.* ; Waldmann, H.* ; Bach, J.F.* ; Pipeleers, D.* ; Chatenoud, L.*
Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes.
N. Engl. J. Med. 352, 2598-2608 (2005)
Schlosser, M.* ; Koczwara, K.* ; Kenk, H.* ; Strebelow, M.* ; Rjasanowski, I.* ; Wassmuth, R.* ; Achenbach, P.* ; Ziegler, A.-G.* ; Bonifacio, E.*
In insulin-autoantibody-positive children from the general population, antibody affinity identifies those at high and low risk.
Diabetologia 48, 1830-1832 (2005)
Schröder, O.* ; Turak, S.* ; Daniel, C.* ; Gaschott, T.* ; Stein, J.*
Upregulation of 25-hydroxyvitamin D(3)-1(alpha)-hydroxylase by butyrate in Caco-2 cells.
World J. Gastroenterol. 11, 7136-7141 (2005)
Toschke, A.M.* ; Beyerlein, A.* ; von Kries, R.*
Children at high risk for overweight: A classification and regression trees analysis approach.
Obesity 13, 1270-1274 (2005)
Viskari, H.* ; Ludvigsson, J.* ; Uibo, R.* ; Salur, L.* ; Marciulionyte, D.* ; Hermann, R.* ; Soltesz, G.* ; Füchtenbusch, M.* ; Ziegler, A.-G.* ; Kondrashova, A.* ; Romanov, A.* ; Kaplan, B.* ; Laron, Z.* ; Koskela, P.* ; Vesikari, T.* ; Huhtala, H.* ; Knip, M.* ; Hyoty, H.*
Relationship between the incidence of type 1 diabetes and maternal enterovirus antibodies: time trends and geographical variation.
Diabetologia 48, 1280-1287 (2005)
Warncke, K.
Charakterisierung der humoralen Autoimmunität im Verlauf der präklinischen Phase des Typ 1 Diabetes.
München, Ludwig-Maximilians-Universität, Medizinische Fakultät, Diss., 2005, 88 S.
Achenbach, P.* ; Füchtenbusch, M.*
Modulating the autoimmune response in type 1 diabetes: A report on the 64th scientific sessions of the ADA, June 2004, Orlando, FL, USA.
Rev. Diabet. Stud. 1, 137-140 (2004)
Achenbach, P.* ; Warncke, K.* ; Reiter, J.* ; Naserke, H.E.* ; Williams, A.J.* ; Bingley, P.J.* ; Bonifacio, E.* ; Ziegler, A.-G.*
Stratification of type 1 diabetes risk on the basis of islet autoantibody characteristics.
Diabetes 53, 384-392 (2004)
Achenbach, P.* ; Koczwara, K.* ; Knopff, A.* ; Naserke, H.E.* ; Ziegler, A.-G.* ; Bonifacio, E.*
Mature high-affinity immune responses to (pro)insulin anticipate the autoimmune cascade that leads to type 1 diabetes.
J. Clin. Invest. 114, 589-597 (2004)
Bonifacio, E.* ; Hummel, M.* ; Walter, M.C.* ; Schmid, S.* ; Ziegler, A.-G.*
IDDM1 and multiple family history of type 1 diabetes combine to identify neonates at high risk for type 1 diabetes.
Diabetes Care 27, 2695-2700 (2004)
Daniel, C.* ; Schröder, O.* ; Zahn, N.* ; Gaschott, T.* ; Stein, J.*
p38 MAPK signaling pathway is involved in butyrate-induced vitamin D receptor expression.
Biochem. Biophys. Res. Commun. 324, 1220-1226 (2004)
Füchtenbusch, M.* ; Bonifacio, E.* ; Lampasona, V.* ; Knopff, A.* ; Ziegler, A.-G.*
Immune responses to glutamic acid decarboxylase and insulin in patients with gestational diabetes.
Clin. Exp. Immunol. 135, 318-321 (2004)
Füchtenbusch, M.* ; Ziegler, A.-G.* ; Hummel, M.*
Elimination of dietary gluten and development of type 1 diabetes in high risk subjects.
Rev. Diabet. Stud. 1, 39-41 (2004)
Hummel, M.* ; Bonifacio, E.* ; Schmid, S.* ; Walter, M.C.* ; Knopff, A.* ; Ziegler, A.-G.*
Brief communication: Early appearance of islet autoantibodies predicts childhood type 1 diabetes in offspring of diabetic parents.
Ann. Intern. Med. 140, 882-886 (2004)
Hummel, M.* ; Ziegler, A.-G.* ; Roth, R.*
Psychological impact of childhood islet autoantibody testing in families participating in the BABYDIAB study.
Diabetic Med. 21, 324-328 (2004)
Koczwara, K.
Immuninterventionen zum Erhalt der beta-Zellfunktion im murinen und humanen Autoimmundiabetes.
München, Technische Universität, Fakultät Wissenschaftszentrum Weihenstephan, Diss., 2004, 137 S.
Koczwara, K.* ; Bonifacio, E.* ; Ziegler, A.-G.*
Transmission of maternal islet antibodies and risk of autoimmune diabetes in offspring of mothers with type 1 diabetes.
Diabetes 53, 1-4 (2004)
Koczwara, K.* ; Ziegler, A.-G.* ; Bonifacio, E.*
Maternal immunity to insulin does not affect diabetes risk in progeny of non obese diabetic mice.
Clin. Exp. Immunol. 136, 56-59 (2004)
Lindsay, R.S.* ; Ziegler, A.-G.* ; Hamilton, B.A.* ; Calder, A.A.* ; Johnstone, F.D.* ; Walker, J.D.*
Type 1 diabetes-related antibodies in the fetal circulation: Prevalence and influence on cord insulin and birth weight in offspring of mothers with type 1 diabetes.
J. Clin. Endocrinol. Metab. 89, 3436-3439 (2004)
Schmid, S.* ; Koczwara, K.* ; Schwinghammer, S.* ; Lampasona, V.* ; Ziegler, A.-G.* ; Bonifacio, E.*
Delayed exposure to wheat and barley proteins reduces diabetes incidence in non-obese diabetic mice.
Clin. Immunol. 111, 108-118 (2004)
Schmid, S.* ; Buuck, D.* ; Knopff, A.* ; Bonifacio, E.* ; Ziegler, A.-G.*
BABYDIET, a feasibility study to prevent the appearance of islet autoantibodies in relatives of patients with type 1 diabetes by delaying exposure to gluten.
Diabetologia 47, 1130-1131 (2004)
Viskari, H.* ; Ludvigsson, J.* ; Uibo, R.* ; Salur, L.* ; Marciulionyte, D.* ; Hermann, R.* ; Soltesz, G.* ; Füchtenbusch, M.* ; Ziegler, A.-G.* ; Kondrashova, A.* ; Romanov, A.* ; Knip, M.* ; Hyoty, H.*
Relationship between the incidence of type 1 diabetes and enterovirus infections in different European populations: Results from the EPIVIR project.
J. Med. Virol. 72, 610-617 (2004)
Füchtenbusch, M.* ; Vogel, A.* ; Achenbach, P.* ; Gummer, M.* ; Ziegler, A.-G.* ; Albert, E.* ; Standl, E.* ; Manns, M.P.*
Lupus-like panniculitis in a patient with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED).
Exp. Clin. Endocrinol. Diabet. 111, 288-293 (2003)
Herbon, N. ; Werner, M. ; Braig, C. ; Gohlke, H. ; Dütsch, G. ; Illig, T. ; Altmüller, J. ; Hampe, J.* ; Lantermann, A.* ; Schreiber, S.* ; Bonifacio, E.* ; Ziegler, A.-G.* ; Schwab, S.* ; Wildenauer, D.* ; van den Boom, D.* ; Braun, A.* ; Knapp, M.* ; Reitmeir, P. ; Wjst, M.
High-resolution SNP scan of chromosome 6p21 in pooled samples from patients with complex diseases.
Genomics 81, 510-518 (2003)
Koczwara, K.* ; Schenker, M.* ; Schmid, S.* ; Kredel, K.* ; Ziegler, A.-G.* ; Bonifacio, E.*
Characterization of antibody responses to endogenous and exogenous antigen in the nonobese diabetic mouse.
Clin. Immunol. 106, 155-162 (2003)
Walter, M.C.* ; Albert, E.* ; Conrad, M.* ; Keller, E.* ; Hummel, M.* ; Ferber, K.* ; Barratt, B.J.* ; Todd, J.A.* ; Ziegler, A.-G.* ; Bonifacio, E.*
IDDM2/insulin VNTR modifies risk conferred by IDDM1/HLA for development of Type 1 diabetes and associated autoimmunity.
Diabetologia 46, 712-720 (2003)
Ziegler, A.-G.* ; Schmid, S.* ; Huber, D.* ; Hummel, M.* ; Bonifacio, E.*
Early infant feeding and risk of developing type 1 diabetes-associated autoantibodies.
JAMA 290, 1721-1728 (2003)
Bearzatto, M.* ; Naserke, H.E.* ; Piquer, S.* ; Koczwara, K.* ; Lampasona, V.* ; Williams, A.* ; Christie, M.R.* ; Bingley, P.J.* ; Ziegler, A.-G.* ; Bonifacio, E.*
Two distinctly HLA-associated contiguous linear epitopes uniquely expressed within the islet antigen 2 molecule are major autoantibody epitopes of the diabetes-specific tyrosine phosphatase-like protein autoantigens.
J. Immunol. 168, 4202-4208 (2002)
Durinovic-Bellò, I.* ; Boehm, B.O.* ; Ziegler, A.-G.*
Predominantly recognized proinsulin T helper cell epitopes in individuals with and without islet cell autoimmunity.
J. Autoimmun. 18, 55-66 (2002)
Eiden, S.* ; Daniel, C.* ; Steinbrueck, A.* ; Schmidt, I.* ; Simon, E.*
Salmon calcitonin - a potent inhibitor of food intake in states of impaired leptin signalling in laboratory rodents.
J. Physiol. 541, 1041-1048 (2002)
Hummel, M.* ; Bonifacio, E.* ; Naserke, H.E.* ; Ziegler, A.-G.*
Elimination of dietary gluten does not reduce titers of type 1 diabetes-associated autoantibodies in high-risk subjects.
Diabetes Care 25, 1111-1116 (2002)
Schmid, S.* ; Molteni, A.* ; Füchtenbusch, M.* ; Naserke, H.E.* ; Ziegler, A.-G.* ; Bonifacio, E.*
Reduced il-4 associated immune responses in early pre-diabetes.
Diabetologia 45, 677-685 (2002)
Schnell, O.* ; Hammer, K.* ; Muhr-Becker, D.* ; Ziegler, A.-G.* ; Weiss, M.* ; Tatsch, K.* ; Standl, E.*
Cardiac sympathetic dysinnervation in Type 2 diabetes mellitus with and without ECG-based cardiac autonomic neuropathy.
J. Diab. Complic. 16, 220-227 (2002)
Bingley, P.J.* ; Bonifacio, E.* ; Ziegler, A.-G.* ; Schatz, D.A.* ; Atkinson, M.A.* ; Eisenbarth, G.S.*
Proposed guidelines on screening for risk of type 1 diabetes.
Diabetes Care 24, 398 (2001)
Füchtenbusch, M.* ; Irnstetter, A.* ; Jäger, G.* ; Ziegler, A.-G.*
No evidence for an association of coxsackie virus infections during pregnancy and early childhood with development of islet autoantibodies in offspring of mothers or fathers with type 1 diabetes.
J. Autoimmun. 17, 333-340 (2001)
Hummel, M.* ; Heinlein, W.* ; Banholzer, P.* ; Standl, E.* ; Ziegler, A.-G.*
Erstmanifestation eines Typ-1-Diabetes mit Anämie, Hyperparathyreodismus und abdomineller Lymphadenomatose.
Internist 42, 279-283 (2001)
Hummel, M.* ; Ziegler, A.-G.*
Environmental factors and type 1 diabetes - Response to G. Dahlquist.
Diabetes Care 24, 181-182 (2001)
Hummel, M.* ; Schenker, M.* ; Ziegler, A.-G.*
Influence of perinatal factors on the appearance of islet autoantibodies in offspring of parents with type 1 diabetes.
Pediatr. Diabetes 2, 40-42 (2001)
Hummel, M.* ; Ziegler, A.-G.* ; Lewy, H.* ; Ashkenazi, I.* ; Laron, Z.*
IAA/GAD-positive offspring of diabetic parents have a different seasonality in month of birth than antibody-negative offspring.
Diabetes Care 24:2001 (2001)
Hummel, M.* ; Williams, A.J.* ; Norcross, A.* ; Standl, E.* ; Bonifacio, E.* ; Ziegler, A.-G.* ; Bingley, P.J.*
Proinsulin-specific autoantibodies are relatively infrequent in young offspring with pre-type 1 diabetes.
Diabetes Care 24, 1843-1844 (2001)
Naserke, H.E.* ; Bonifacio, E.* ; Ziegler, A.-G.*
Prevalence, characteristics and diabetes risk associated with transient maternally acquired islet antibodies and persistent islet antibodies in offspring of parents with type 1 diabetes.
J. Clin. Endocrinol. Metab. 86, 4826-4833 (2001)
Schmid, S.* ; Schnell, O.* ; Bonifacio, E.* ; Ziegler, A.-G.* ; Hummel, M.*
Silent coeliac disease is not a cause of autonomic neuropathy in patients with Type 1 diabetes.
Diabetic Med. 18, 686-687 (2001)
Bonifacio, E.* ; Lampasona, V.* ; Bernasconi, L.* ; Ziegler, A.-G.*
Maturation of the humoral autoimmune response to epitopes of GAD in preclinical childhood type 1 diabetes.
Diabetes 49, 202-208 (2000)
Füchtenbusch, M.* ; Kredel, K.* ; Bonifacio, E.* ; Schnell, O.* ; Ziegler, A.-G.*
Exposure to exogenous insulin promotes IgG1 and the T-helper 2-associated IgG4 responses to insulin but not to other islet autoantigens.
Diabetes 49, 918-925 (2000)
Hummel, M.* ; Füchtenbusch, M.* ; Schenker, M.* ; Ziegler, A.-G.*
No major association of breast-feeding, vaccinations, and childhood viral diseases with early islet autoimmunity in the German BABYDIAB study.
Diabetes Care 23, 969-974 (2000)
Hummel, M.* ; Bonifacio, E.* ; Stern, M.* ; Dittler, J.* ; Schimmel, A.* ; Ziegler, A.-G.*
Development of celiac disease-associated antibodies in offspring of parents with type I diabetes.
Diabetologia 43, 1005-1011 (2000)
Kolm-Litty, V.* ; Berlo, S.* ; Bonifacio, E.* ; Bearzatto, M.* ; Engel, A.M.* ; Christie, M.* ; Ziegler, A.-G.* ; Wild, T.* ; Endl, J.*
Human monoclonal antibodies isolated from type I diabetes patients define multiple epitopes in the protein tyrosine phosphatase-like IA-2 antigen.
J. Immunol. 165, 4676-4684 (2000)
Roll, U.* ; Turck, C.W.* ; Gitelman, S.E.* ; Rosenthal, S.M.* ; Nolte, M.S.* ; Masharani, U.* ; Ziegler, A.-G.* ; Baekkeskov, S.*
Peptide mapping and characterisation of glycation patterns of the glima 38 antigen recognised by autoantibodies in Type I diabetic patients.
Diabetologia 43, 598-608 (2000)
Ziegler, A.-G.* ; Bonifacio, E.*
No inverse relationship between total IgE levels and islet autoimmunity in children of parents with type 1 diabetes.
Diabetes Care 23, 1205-1206 (2000)
Bonifacio, E.* ; Scirpoli, M.* ; Kredel, K.* ; Füchtenbusch, M.* ; Ziegler, A.-G.*
Early autoantibody responses in prediabetes are IgG1 dominated and suggest antigen-specific regulation.
J. Immunol. 163, 525-532 (1999)
Eaves, I.A.* ; Bennett, S.T.* ; Forster, P.* ; Ferber, K.M.* ; Ehrmann, D.* ; Wilson, A.J.* ; Bhattacharyya, S.* ; Ziegler, A.-G.* ; Brinkmann, B.* ; Todd, J.A.*
Transmission ratio distortion at the INS-IGF2 VNTR.
Nat. Genet. 22, 324-325 (1999)
Ferber, K.M.* ; Keller, E.* ; Albert, E.D.* ; Ziegler, A.-G.*
Predictive value of human leukocyte antigen class II typing for the development of islet autoantibodies and insulin-dependent diabetes postpartum in women with gestational diabetes.
J. Clin. Endocrinol. Metab. 84, 2342-2348 (1999)
Naserke, H.E.* ; Bonifacio, E.* ; Ziegler, A.-G.*
Immunoglobulin G insulin autoantibodies in BABYDIAB offspring appear postnatally: sensitive early detection using a protein A/G-based radiobinding assay.
J. Clin. Endocrinol. Metab. 84, 1239-1243 (1999)
Naserke, H.E.* ; Schenker, M.* ; Ziegler, A.-G.*
Frequency of islet autoantibodies in relatives of patients with Type II diabetes or gestational diabetes.
Diabetologia 42, 1377-1377 (1999)
Schenker, M.* ; Hummel, M.* ; Ferber, K.* ; Walter, M.C.* ; Keller, E.* ; Albert, E.D.* ; Janka, H.U.* ; Kastendiek, C.* ; Sorger, M.* ; Louwen, F.* ; Ziegler, A.-G.*
Early expression and high prevalence of islet autoantibodies for DR3/4 heterozygous and DR4/4 homozygous offspring of parents with Type I diabetes: the German BABYDIAB study.
Diabetologia 42, 671-677 (1999)
Ziegler, A.-G.* ; Hummel, M.* ; Schenker, M.* ; Bonifacio, E.*
Autoantibody appearance and risk for development of childhood diabetes in offspring of parents with type 1 diabetes: The 2-year analysis of the German BABYDIAB study.
Diabetes 48, 460-468 (1999)
Dittler, J.* ; Seidel, D.* ; Schenker, M.* ; Ziegler, A.-G.*
GADIA2-combi determination as first-line screening for improved prediction of type 1 diabetes in relatives.
Diabetes 47, 592-597 (1998)
Füchtenbusch, M.* ; Rabl, W.* ; Grassl, B.* ; Bachmann, W.* ; Standl, E.* ; Ziegler, A.-G.*
Delay of type I diabetes in high risk, first degree relatives by parenteral antigen administration: The Schwabing Insulin Prophylaxis Pilot Trial.
Diabetologia 41, 536-541 (1998)
Hummel, M.* ; Durinovic-Bellò, I.* ; Bonifacio, E.* ; Lampasona, V.* ; Endl, J.* ; Fessele, S.* ; Then Bergh, F.* ; Trenkwalder, C.* ; Standl, E.* ; Ziegler, A.-G.*
Humoral and cellular immune parameters before and during immunosuppressive therapy of a patient with stiff-man syndrome and insulin dependent diabetes mellitus.
J. Neurol. Neurosurg. Psychiatr. 65, 204-208 (1998)
Hummel, M.* ; Banholzer, P.* ; Rabl, W.* ; Ziegler, A.-G.*
Organospecific lymph node enlargement in autoimmune polyglandular syndrome.
Diabetes Care 21, 1573-1574 (1998)
Muhr-Becker, D.* ; Ziegler, A.-G.* ; Druschky, A.* ; Wolfram, G.* ; Haslbeck, M.* ; Neundörfer, B.* ; Standl, E.* ; Schnell, O.*
Evidence for specific autoimmunity against sympathetic and parasympathetic nervous tissues in Type 1 diabetes mellitus and the relation to cardiac autonomic dysfunction.
Diabetic Med. 15, 467-472 (1998)
Naserke, H.E.* ; Dozio, N.* ; Ziegler, A.-G.* ; Bonifacio, E.*
Comparison of a novel micro-assay for insulin autoantibodies with the conventional radiobinding assay.
Diabetologia 41, 681-683 (1998)
Naserke, H.E.* ; Ziegler, A.-G.* ; Lampasona, V.* ; Bonifacio, E.*
Early development and spreading of autoantibodies to epitopes of IA-2 and their association with progression to type 1 diabetes.
J. Immunol. 161, 6963-6969 (1998)
Seidel, D.K.* ; Geiss, H.C.* ; Donner, M.G.* ; Ritter, M.M.* ; Schwandt, P.* ; Koll, R.A.* ; Standl, E.* ; Ziegler, A.-G.*
Course of islet autoantibody titers during Ig-immunoadsorption in a patient with newly diagnosed type 1 diabetes.
J. Autoimmun. 11, 273-277 (1998)
Christie, M.R.* ; Roll, U.* ; Payton, M.A.* ; Hatfield, E.C.* ; Ziegler, A.-G.*
Validity of screening for individuals at risk for type I diabetes by combined analysis of antibodies to recombinant proteins.
Diabetes Care 20, 965-970 (1997)
Endl, J.* ; Otto, H.* ; Jung, G.* ; Dreisbusch, B.* ; Donie, F.* ; Stahl, P.* ; Elbracht, R.* ; Schmitz, G.* ; Meinl, E.* ; Hummel, M.* ; Ziegler, A.-G.* ; Wank, R.* ; Schendel, D.J.*
Identification of naturally processed T cell epitopes from glutamic acid decarboxylase presented in the context of HLA-DR alleles by T lymphocytes of recent onset IDDM patients.
J. Clin. Invest. 99, 2405-2415 (1997)
Füchtenbusch, M.* ; Karges, W.* ; Standl, E.* ; Dosch, H.M.* ; Ziegler, A.-G.*
Antibodies to Bovine Serum Albumin (BSA) in type 1 diabetes and other autoimmune disorders.
Exp. Clin. Endocrinol. Diabet. 105, 86-91 (1997)
Füchtenbusch, M.* ; Ferber, K.* ; Standl, E.* ; Ziegler, A.-G.*
Prediction of type 1 diabetes postpartum in patients with gestational diabetes mellitus by combined islet cell autoantibody screening: A prospective multicenter study.
Diabetes 46, 1459-1467 (1997)
Muhr, D.* ; Mollenhauer, U.* ; Ziegler, A.-G.* ; Haslbeck, M.* ; Standl, E.* ; Schnell, O.*
Autoantibodies to sympathetic ganglia, GAD, or tyrosine phosphatase in long-term IDDM with and without ECG-based cardiac autonomic neuropathy.
Diabetes Care 20, 1009-1012 (1997)
Schnell, O.* ; Eisfelder, B.* ; Standl, E.* ; Ziegler, A.-G.*
High-dose intravenous insulin infusion versus intensive insulin treatment in newly diagnosed IDDM.
Diabetes 46, 1607-1011 (1997)
Weichenhain, B.* ; Stemplinger, J.* ; Ziegler, A.-G.* ; Rabl, W.* ; Standl, E.* ; Stiegler, H.*
Alström-Syndrom — eine seltene Erkrankung aus dem diabetischen Formenkreis.
Med. Klin. Intensivmed. Notfmed. 92, 175-178 (1997)
Bingley, P.J.*
Interactions of age, islet cell antibodies, insulin autoantibodies, and first-phase insulin response in predicting risk of progression to IDDM in ICA+ relatives: The ICARUS data set.
Diabetes 45, 1720-1728 (1996)
Durinovic-Bellò, I.* ; Hummel, M.* ; Ziegler, A.-G.*
Cellular immune response to diverse islet cell antigens in IDDM.
Diabetes 45, 795-800 (1996)
Hummel, M.* ; Durinovic-Bellò, I.* ; Ziegler, A.-G.*
Relation between cellular and humoral immunity to islet cell antigens in type 1 diabetes.
J. Autoimmun. 9, 427-430 (1996)
Hummel, M.* ; Ziegler, A.-G.*
Vaccines and the appearance of islet cell antibodies in offspring of diabetic parents. Results from the BABY-DIAB study.
Diabetes Care 19, 1456-1457 (1996)
Mayrhofer, M.* ; Rabin, D.U.* ; Messenger, L.* ; Standl, E.* ; Ziegler, A.-G.*
Value of ICA512 antibodies for prediction and diagnosis of type 1 diabetes.
Exp. Clin. Endocrinol. Diabet. 104, 228-234 (1996)
Naserke, H.E.* ; Durinovic-Bellò, I.* ; Seidel, D.* ; Ziegler, A.-G.*
The T-cell receptor beta chain CDR3 region of BV8S1/BJ1S5 transcripts in type 1 diabetes.
Immunogenetics 45, 87-96 (1996)
Roll, U.* ; Christie, M.R.* ; Füchtenbusch, M.* ; Payton, M.A.* ; Hawkes, C.J.* ; Ziegler, A.-G.*
Perinatal autoimmunity in offspring of diabetic parents. The German Multicenter BABY-DIAB study: detection of humoral immune responses to islet antigens in early childhood.
Diabetes 45, 967-973 (1996)
Schnell, O.* ; Muhr, D.* ; Dresel, S.* ; Tatsch, K.* ; Ziegler, A.-G.* ; Haslbeck, M.* ; Standl, E.*
Autoantibodies against sympathetic ganglia and evidence of cardiac sympathetic dysinnervation in newly diagnosed and long-term IDDM patients.
Diabetologia 39, 970-975 (1996)
Roll, U.* ; Nuber, A.* ; Schröder, A.* ; Gerlach, E.* ; Janka, H.U.* ; Ziegler, A.-G.*
No association of antibodies to glutamic acid decarboxylase and diabetic complications in patients with IDDM.
Diabetes Care 18, 210-215 (1995)
Baumgartl, H.J.* ; Trucco, M.* ; Albert, E.* ; Mehnert, S.* ; Knapp, M.* ; Standl, E.* ; Ziegler, A.-G.*
Assoziation von HLA-DQ-Markern und Typ-I-Diabetes in süddeutschen Multiplexfamilien
Diabetes Stoffwechs. 3, 278-282 (1994)
Durinovic-Bellò, I.* ; Steinle, A.* ; Ziegler, A.-G.* ; Schendel, D.J.*
HLA-DQ-restricted, islet-specific T-cell clones of a type I diabetic patient. T-cell receptor sequence similarities to insulitis-inducing T-cells of nonobese diabetic mice.
Diabetes 43, 1318-1325 (1994)
Roll, U.* ; Christie, M.R.* ; Standl, E.* ; Ziegler, A.-G.*
Associations of anti-GAD antibodies with islet cell antibodies and insulin autoantibodies in first-degree relatives of type I diabetic patients.
Diabetes 43, 154-160 (1994)
Roll, U.* ; Scheeser, J.* ; Standl, E.* ; Ziegler, A.-G.*
Alterations of lymphocyte subsets in children of diabetic mothers.
Diabetologia 37, 1132-1141 (1994)
Castaño, L.* ; Ziegler, A.-G.* ; Ziegler, R.* ; Shoelson, S.* ; Eisenbarth, G.S.*
Characterization of insulin autoantibodies in relatives of patients with type I diabetes.
Diabetes 42, 1202-1209 (1993)
Ziegler, A.-G.* ; Mathies, R.* ; Ziegelmayer, G.* ; Baumgartl, H.J.* ; Rodewald, A.* ; Chopra, V.* ; Standl, E.*
Dermatoglyphics in type 1 diabetes mellitus.
Diabetic Med. 10, 720-724 (1993)
Ziegler, A.-G.* ; Hillebrand, B.* ; Rabl, W.* ; Mayrhofer, M.* ; Hummel, M.* ; Mollenhauer, U.* ; Vordemann, J.* ; Lenz, A.-G.* ; Standl, E.*
On the appearance of islet associated autoimmunity in offspring of diabetic mothers: A prospective study from birth.
Diabetologia 36, 402-408 (1993)
Ziegler, A.-G.* ; Hillebrand, B.* ; Standl, E.*
Inselzellantikörper und Insulin Autoantikörper bei Schwangeren mit Gestationsdieabetes
Diabetes Stoffwechs. 2, 51-55 (1993)
Martin, S.* ; Pawlowski, B.* ; Greulich, B.* ; Ziegler, A.-G.* ; Mandrup-Poulsen, T.* ; Mahon, J.*
Natural course of remission in IDDM during 1st yr after diagnosis.
Diabetes Care 15, 66-74 (1992)
Ziegler, A.-G.* ; Baumgartl, H.J.* ; Mühlbauer, K.* ; Mehnert, S.* ; Standl, E.*
Familienuntersuchung bei Typ 1 Diabetes. Hinweise für eine  gemeinsame genetische Komponente von Typ-1- und Typ-2-Diabetes
Diabetes Stoffwechs. 1, 14-17 (1992)
Ziegler, A.-G.* ; Erhard, J.* ; Lampeter, E.F.* ; Nagelkerken, L.M.* ; Standl, E.*
Involvement of dendritic cells in early insulitis of BB rats.
J. Autoimmun. 5, 571-579 (1992)
Baumgartl, H.J.* ; Standl, E.* ; Schmidt-Gayk, H.* ; Kolb, H.J.* ; Janka, H.U.* ; Ziegler, A.-G.*
Changes of vitamin D3 serum concentrations at the onset of immune-mediated type 1 (insulin-dependent) diabetes mellitus.
Diabetes Res. Clin. Pract. 16, 145-148 (1991)
van Kooten, H.-J.  ; Standl, R. ; Stiegler, H. ; Rebell, B. ; Ziegler, A.-G. ; Schauer, G. ; Roth, R. ; Schulz, K. ; Lehmacher, W. ; Standl, E.
Der Typ-II-Diabetes in der Praxis des niedergelassenen Arztes: Konzept einer zentrumunterstützten Betreuung und einer Stichproben-Erhebung im Großraum München.
Akt. Endokr. Stoffw. 12, S. 268 (1991)
Zelles, L.* ; Adrian, P.* ; Bai, Q.* ; Stepper, K.* ; Adrian, M.V.* ; Fischer, K. ; Maier, A.* ; Ziegler, A.-G.*
Microbial activity measured in soils stored under different temperature and humidity conditions.
Soil Biol. Biochem. 23, 955-962 (1991)
Ziegler, A.-G.* ; Standl, E.* ; Albert, E.* ; Mehnert, H.*
HLA-associated insulin autoantibody formation in newly diagnosed type I diabetic patients.
Diabetes 40, 1146-1149 (1991)
Ziegler, A.-G.* ; Rabl, W.* ; Albert, E.* ; Standl, E.*
Insulin-Autoantikörper und Inselzell-Antikörper in Abhänigkeit vom Manifestetionsalter und HLA Phänotyp bei Patienten mit neumanifestem Typ-I-Diabetes.
Dtsch. Med. Wochenschr. 116, 1737-1741 (1991)
Standl, R. ; Stiegler, H. ; Rebell, B. ; Ziegler, A.-G. ; Schauer, G. ; Roth, R. ; Schulz, K. ; Lehmacher, W. ; Standl, E.
Der Typ-II-Diabetes in der Praxis des niedergelassenen Arztes:  Konzept einer zentrumsunterstützten Betreuung und Ergebnisse einer Stichproben-Erhebung im Großraum München.
Akt. Endokr. Stoffw. 11, 222-228 (1990)
Stiegler, H. ; Standl, E. ; Standl, R. ; Rebell, B. ; Ziegler, A.-G. ; Janka, H.U. ; Schulz, K. ; Roth, R. ; Lehmacher, W.
Risikoprofil und Makroangiopathie bei Typ-II Diabetikern in der ärztlichen Praxis.
Vasa 19, 119-128 (1990)
Ziegler, A.-G.* ; Baumgartl, H.J.* ; Standl, E.* ; Mehnert, H.*
Risk of progression to diabetes of low titer ICA-positive first-degree relatives of type I diabetics in southern Germany.
J. Autoimmun. 3, 619-624 (1990)
Ziegler, A.-G.* ; Baumgartl, H.J.* ; Ede, G.* ; Held, M.* ; Vogt, H.-J.* ; Kolb, H.J.* ; Standl, E.*
Low-pigment skin type and predisposition for development of type I diabetes.
Diabetes Care 13, 529-531 (1990)
Janka, H.U.* ; Ziegler, A.-G.* ; Valsania, P.* ; Warram, J.H.* ; Krolewski, A.S.*
Impact of blood pressure on diabetic retinopathy.
Diabete & Metabolisme 15, 333-337 (1989)
Janka, H.U.* ; Ziegler, A.-G.* ; Larrat, V.* ; Mehnert, H.*
The effect of the beta 1 selective beta blocker, betaxolol, on metabolism in type II diabetics.
Arzneim. Forsch. 39, 615-617 (1989)
Ziegler, A.-G.* ; Vardi, P.* ; Ricker, A.T.* ; Hattori, M.* ; Soeldner, J.S.* ; Eisenbarth, G.S.*
Radioassay determination of insulin autoantibodies in NOD mice. Correlation with increased risk of progression to overt diabetes.
Diabetes 38, 358-363 (1989)
Ziegler, A.-G.* ; Vardi, P.* ; Gross, D.J.* ; Bonner-Weir, S.* ; Villa-Komaroff, L.* ; Halban, P.A.* ; Ikegami, H.* ; Soeldner, J.S.* ; Eisenbarth, G.S.*
Production of insulin antibodies by mice rejecting insulin transfected cells.
J. Autoimmun. 2, 219-227 (1989)
Ziegler, A.-G.* ; Ziegler, R.* ; Vardi, P.* ; Jackson, R.A.* ; Soeldner, J.S.* ; Eisenbarth, G.S.*
Life-table analysis of progression to diabetes of anti-insulin autoantibodys positive relatives of type 1 diabetics
Diabetes 38, 1320-1325 (1989)
Park, J.W.* ; Ziegler, A.-G.* ; Janka, H.U.* ; Doering, W.* ; Mehnert, H.*
Left ventricular relaxation and filling pattern in diabetic heart muscle disease: An echocardiographic study.
Klin. Wochenschr. 66, 773-778 (1988)
Vardi, P.* ; Ziegler, A.-G.* ; Mathews, J.H.* ; Dib, S.* ; Keller, R.J.* ; Ricker, A.T.* ; Wolfsdorf, J.I.* ; Herskowitz, R.D.* ; Rabizadeh, A.* ; Eisenbarth, G.S.*
Concentration of insulin autoantibodies at onset of type I diabetes. Inverse log-linear correlation with age.
Diabetes Care 11, 736-739 (1988)
Ziegler, A.-G.* ; Standl, E.*
Loss of Ia-positive epidermal Langerhans cells at the onset of type 1 (insulin-dependent) diabetes mellitus.
Diabetologia 31, 632-635 (1988)
Canadian-European Randomized Control Trial Group (Ziegler, A.-G.*)
Cyclosporin-induced remission of IDDM after early intervention. Association of 1 yr of cyclosporin treatment with enhanced insulin secretion. The Canadian-European Randomized Control Trial Group.
Diabetes 37, 1574-1582 (1988)
Janka, H.U.* ; Ziegler, A.-G.* ; Standl, E.* ; Mehnert, H.*
Daily insulin dose as a predictor of macrovascular disease in insulin treated non-insulin-dependent diabetics.
Diabetic Med. 13, 359-364 (1987)
Janka, H.U.* ; Ziegler, A.-G.* ; Huber, A.* ; Mehnert, H.*
Type II diabetes. Effects of nifedipine in comparison to a combination of mefruside and acebutolol.
Dtsch. Med. Wochenschr. 129, 594-596 (1987)
Ziegler, A.-G.* ; Janka, H.U.* ; Mehnert, H.*
Transitorische ischämische Attacken bei Hyperparathyreoidismus
Dtsch. Med. Wochenschr. 112, 345-346 (1987)
Ziegler, A.-G.* ; Janka, H.U.* ; Mehnert, H.*
Cell mediated auotimmunity at the onset of Type I diabetes mellitus
Klin. Wochenschr. 65, 546-550 (1987)
Ziegler, A.-G.* ; Janka, H.U.* ; Mehnert, H.*
Transient ischemic attacks in primary hyperparathyroidism. Prevention with calcium antagonists.
Dtsch. Med. Wochenschr. 112, 345-346 (1987)
Ziegler, A.-G.* ; Standl, E.*
Type I diabetes mellitus: Immunopathogenesis and chances of primary immunotherapy.
Med. Klin. Intensivmed. Notfmed. 82, 796-800 (1987)
Janka, H.U.* ; Ziegler, A.-G.* ; Disselhoff, G.* ; Mehnert, H.*
Influence of bisoprolol on blood glucose glycosuria and haemoglobin a1 in non insulin-dependent diabetics.
J. Cardiovasc. Pharmacol. 8, S96-S99 (1986)
Ziegler, A.-G.* ; Janka, H.U.* ; Meister, P.* ; Spelsberg, F.* ; Mehnert, H.*
Multiple endokrine Neoplastie Typ IIb mit Ganglioneuromatose der Gallenblase, Cholelithiasis und Kleinhirndysplasie.
Akt. Endokr. Stoffw. 7, 156-159 (1986)