Richter, L.* ; Munter, L.M.* ; Ness, J.* ; Hildebrand, P.W.* ; Dasari, M.* ; Unterreitmeier, S.* ; Bulic, B.* ; Beyermann, M.* ; Gust, R.* ; Reif, B.* ; Weggen, S.* ; Langosch, D.* ; Multhaup, G.*
Amyloid beta 42 peptide (Abeta42)-lowering compounds directly bind to Abeta and interfere with amyloid precursor protein (APP) transmembrane dimerization.
Proc. Natl. Acad. Sci. U.S.A. 107, 14597-14602 (2010)
Simon, B.* ; Madl, T. ; Mackereth, C.D.* ; Nilges, M.* ; Sattler, M.
An efficient protocol for NMR-spectroscopy-based structure determination of protein complexes in solution.
Angew. Chem.-Int. Edit. 49, 1967-1970 (2010)
Sushko, I. ; Novotarskyi, S. ; Körner, R. ; Pandey, A.K. ; Kovalishyn, V.V.* ; Prokopenko, V.V.* ; Tetko, I.V.
Applicability domain for in silico models to achieve accuracy of experimental measurements.
J. Chemometr. 24, 202-208 (2010)
Sushko, I. ; Novotarskyi, S. ; Körner, R. ; Pandey, A.K. ; Cherkasov, A.* ; Li, J.* ; Gramatica, P.* ; Hansen, K.* ; Schroeter, T.* ; Müller, K.R.* ; Xi, L.* ; Liu, H.* ; Yao, X.* ; Öberg, T.* ; Hormozdiari, F.* ; Dao, P.* ; Sahinalp, C.* ; Todeschini, R.* ; Polishchuk, P.* ; Artemenko, A.* ; Kuz'min, V.* ; Martin, T.M.* ; Young, D.M.* ; Fourches, D.* ; Muratov, E.* ; Tropsha, A.* ; Baskin, I.* ; Horvath, D.* ; Marcou, G.* ; Müller, C.* ; Varnek, A.* ; Prokopenko, V.V.* ; Tetko, I.V.
Applicability domains for classification problems: Benchmarking of distance to models for ames mutagenicity set.
J. Chem. Inf. Model. 50, 2094-2111 (2010)
Linser, R.* ; Fink, U.* ; Reif, B.*
Assignment of dynamic regions in biological solids enabled by spin-state selective NMR experiments.
J. Am. Chem. Soc. 132, 8891-8893 (2010)
Chevelkov, V.* ; Xue, Y.* ; Linser, R.* ; Skrynnikov, N.R.* ; Reif, B.*
Comparison of solid-state dipolar couplings and solution relaxation data provides insight into protein backbone dynamics.
J. Am. Chem. Soc. 132, 5015-5017 (2010)
Villa, A.E.* ; Tetko, I.V.
Cross-frequency coupling in mesiotemporal EEG recordings of epileptic patients.
J. Physiol. 104, 197-202 (2010)
Graebsch, A. ; Roche, S. ; Niessing, D.
Ein Baustein des Fragilen X-assozierten Tremor/Ataxie-Syndroms.
BioSpektrum 16, 635-637 (2010)
Rupp, M. ; Körner, R. ; Tetko, I.V.
Estimation of acid dissociation constants using graph kernels.
Mol. Inform. 29, 731-741 (2010)
Hundsrucker, C.* ; Skroblin, P.* ; Christian, F.* ; Zenn, H.M.* ; Popara, V.* ; Joshi, M.* ; Eichhorst, J.* ; Wiesner, B.* ; Herberg, F.W.* ; Reif, B.* ; Rosenthal, W.* ; Klussmann, E.*
Glycogen synthase kinase 3beta interaction protein functions as an A-kinase anchoring protein.
J. Biol. Chem. 285, 5507-5521 (2010)
Asami, S.* ; Schmieder, P.* ; Reif, B.
High resolution 1H-detected solid-state NMR spectroscopy of protein aliphatic resonances: Access to tertiary structure information.
J. Am. Chem. Soc. 132, 15133-15135 (2010)
Agarwal, V.* ; Linser, R.* ; Fink, U.* ; Faelber, K.* ; Reif, B.*
Identification of hydroxyl protons, determination of their exchange dynamics, and characterization of hydrogen bonding in a microcrystallin protein.
J. Am. Chem. Soc. 132, 3187-3195 (2010)
Krushelnitsky, A.* ; Zinkevich, T.* ; Reichert, D.* ; Chevelkov, V.* ; Reif, B.*
Microsecond time scale mobility in a solid protein as studied by the 15N R(1rho) site-specific NMR relaxation rates.
J. Am. Chem. Soc. 132, 11850-11853 (2010)
Linser, R.* ; Fink, U.* ; Reif, B.*
Narrow carbonyl resonances in proton-diluted proteins facilitate NMR assignments in the solid-state.
J. Biomol. NMR 47, 1-6 (2010)
Güttler, T.* ; Madl, T. ; Neumann, P.* ; Deichsel, D.* ; Corsini, L. ; Monecke, T.* ; Ficner, R.* ; Sattler, M. ; Görlich, D.*
NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
Nat. Struct. Mol. Biol. 17, 1367-1376 (2010)
Graebsch, A. ; Roche, S. ; Kostrewa, D.* ; Söding, J.* ; Niessing, D.
Of bits and bugs - on the use of bioinformatics and a bacterial crystal structure to solve a eukaryotic repeat-protein structure.
PLoS ONE 5:e13402 (2010)
Akbey, Ü.* ; Lange, S.* ; Trent Franks, W.* ; Linser, R.* ; Rehbein, K.* ; Diehl, A.* ; van Rossum, B.J.* ; Reif, B.* ; Oschkinat, H.*
Optimum levels of exchangeable protons in perdeuterated proteins for proton detection in MAS solid-state NMR spectroscopy.
J. Biomol. NMR 46, 67-73 (2010)
Lopez del Amo, J.M.* ; Fink, U.* ; Reif, B.
Quantification of protein backbone hydrogen-deuterium exchange rates by solid state NMR spectroscopy.
J. Biomol. NMR 48, 203-212 (2010)
Tripsianes, K. ; Sattler, M.
Repeat recognition.
Structure 18, 1228-1229 (2010)
Madl, T. ; Felli, I.C.* ; Bertini, I.* ; Sattler, M.
Structural analysis of protein interfaces from ¹³C direct-detected paramagnetic relaxation enhancements.
J. Am. Chem. Soc. 132, 7285-7287 (2010)
Meyer, N.H. ; Tripsianes, K. ; Vincendeau, M. ; Madl, T. ; Kateb, F. ; Brack-Werner, R. ; Sattler, M.
Structural basis for homodimerization of the Src-associated during mitosis, 68-kDa protein (Sam68) Qua1 domain.
J. Biol. Chem. 285, 28893-28901 (2010)
Bhushan, S.* ; Meyer, H. ; Starosta, A.L.* ; Becker, T.* ; Mielke, T.* ; Berninghausen, O.* ; Sattler, M. ; Wilson, D.N.* ; Beckmann, R.*
Structural basis for translational stalling by human cytomegalovirus and fungal arginine attenuator peptide.
Mol. Cell 40, 138-146 (2010)
Mourao, A. ; Varrot, A.* ; Mackereth, C.D.* ; Cusack, S.* ; Sattler, M.
Structure and RNA recognition by the snRNA and snoRNA transport factor PHAX.
RNA 16, 1205-1216 (2010)
Friberg, A. ; Oddone, A.* ; Klymenko, T.* ; Müller, J.* ; Sattler, M.
Structure of an atypical Tudor domain in the Drosophila Polycomblike protein.
Protein Sci. 19, 1906-1916 (2010)
Heuck, A. ; Fetka, I.* ; Brewer, D.N.* ; Hüls, D. ; Munson, M.* ; Jansen, R.P.* ; Niessing, D.
The structure of the Myo4p globular tail and its function in ASH1 mRNA localization.
J. Cell Biol. 189, 497-510 (2010)